RCSB PDB: Search

1A5T \| pdb_00001a5t	Download File View File

CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III

Guenther, B., Onrust, R., Sali, A., O'Donnell, M., Kuriyan, J.

(1997) Cell 91: 335-345

Released	1998-05-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli K-12
Macromolecule	DELTA PRIME (protein)
Unique Ligands	ZN

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1BO4 \| pdb_00001bo4	Download File View File

CRYSTAL STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE: SERRATIA MARESCENS AMINOGLYCOSIDE 3-N-ACETYLTRANSFERASE

Wolf, E., Vassilev, A., Makino, Y., Sali, A., Nakatani, Y., Burley, S.K.

(1998) Cell 94: 439-449

Released	1998-10-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Serratia marcescens
Macromolecule	PROTEIN (SERRATIA MARCESCENS AMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE) (protein)
Unique Ligands	COA, SPD

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1CMO \| pdb_00001cmo	Download File View File

IMMUNOGLOBULIN MOTIF DNA-RECOGNITION AND HETERODIMERIZATION FOR THE PEBP2/CBF RUNT-DOMAIN

Nagata, T., Gupta, V., Sorce, D., Kim, W.Y., Sali, A., Chait, B.T., Shigesada, K., Ito, Y., Werner, M.H.

(1999) Nat Struct Biol 6: 615-618

Released	2000-01-05
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	POLYOMAVIRUS ENHANCER BINDING PROTEIN 2 (protein)

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1FI4 \| pdb_00001fi4	Download File View File

THE X-RAY CRYSTAL STRUCTURE OF MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AT 2.3 ANGSTROM RESOLUTION.

Bonanno, J.B., Edo, C., Eswar, N., Pieper, U., Romanowski, M.J., Ilyin, V., Gerchman, S.E., Kycia, H., Studier, F.W., Sali, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2001) Proc Natl Acad Sci U S A 98: 12896-12901

Released	2001-03-21
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE (protein)

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1G61 \| pdb_00001g61	Download File View File

CRYSTAL STRUCTURE OF M.JANNASCHII EIF6

Groft, C.M., Beckmann, R., Sali, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2000) Nat Struct Biol 7: 1156-1164

Released	2000-11-22
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Methanocaldococcus jannaschii
Macromolecule	TRANSLATION INITIATION FACTOR 6 (protein)

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1G62 \| pdb_00001g62	Download File View File

CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6

Groft, C.M., Beckmann, R., Sali, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2000) Nat Struct Biol 7: 1156-1164

Released	2000-11-22
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	RIBOSOME ANTI-ASSOCIATION FACTOR EIF6 (protein)

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1I9A \| pdb_00001i9a	Download File View File

STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE

Bonanno, J.B., Edo, C., Eswar, N., Pieper, U., Romanowski, M.J., Ilyin, V., Gerchman, S.E., Kycia, H., Studier, F.W., Sali, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2001) Proc Natl Acad Sci U S A 98: 12896-12901

Released	2001-03-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (protein)
Unique Ligands	MN

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2GDQ \| pdb_00002gdq	Download File View File

Crystal structure of mandelate racemase/muconate lactonizing enzyme from Bacillus subtilis at 1.8 A resolution

Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Emtage, S., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Burley, S.K., Sali, A., Babbitt, P., Pieper, U., Gerlt, J.A., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)

To be published

Released	2006-04-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bacillus subtilis subsp. subtilis str. 168
Macromolecule	yitF (protein)

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2GGE \| pdb_00002gge	Download File View File

Crystal Structure of Mandelate Racemase/Muconate Lactonizing Enzyme from Bacillus Subtilis complexed with MG++ at 1.8 A

Malashkevich, V.N., Sauder, J.M., Schwinn, K.D., Emtage, S., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Burley, S.K., Sali, A., Babbitt, P., Pieper, U., Gerlt, J.A., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)

To be published

Released	2006-04-18
Method	X-RAY DIFFRACTION 1.89 Å
Organisms	Bacillus subtilis
Macromolecule	yitF (protein)
Unique Ligands	CL, MG

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3B5U \| pdb_00003b5u	Download File View File

Actin filament model from extended form of acromsomal bundle in the Limulus sperm

Cong, Y., Topf, M., Sali, A., Matsudaira, P., Dougherty, M., Chiu, W., Schmid, M.F.

(2008) J Mol Biology 375: 331-336

Released	2008-04-15
Method	ELECTRON CRYSTALLOGRAPHY
Organisms	Oryctolagus cuniculus
Macromolecule	Actin, alpha skeletal muscle (protein)

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3B63 \| pdb_00003b63	Download File View File

Actin filament model in the extended form of acromsomal bundle in the Limulus sperm

Cong, Y., Topf, M., Sali, A., Matsudaira, P., Dougherty, M., Chiu, W., Schmid, M.F.

(2008) J Mol Biology 375: 331-336

Released	2008-11-18
Method	ELECTRON MICROSCOPY 9.5 Å
Organisms	Limulus polyphemus
Macromolecule	Unique protein chains: 7

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3KEP \| pdb_00003kep	Download File View File

Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae

Sampathkumar, P., Ozyurt, S.A., Do, J., Bain, K., Dickey, M., Gheyi, T., Sali, A., Kim, S.J., Phillips, J., Pieper, U., Fernandez-Martinez, J., Franke, J.D., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Rout, M., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2010) Proteins 78: 1992-1998

Released	2009-12-22
Method	X-RAY DIFFRACTION 1.82 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Nucleoporin NUP145 (protein)
Unique Ligands	EDO

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3KES \| pdb_00003kes	Download File View File

Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae in the Hexagonal, P61 space group

Sampathkumar, P., Ozyurt, S.A., Do, J., Bain, K., Dickey, M., Gheyi, T., Sali, A., Kim, S.J., Phillips, J., Pieper, U., Fernandez-Martinez, J., Franke, J.D., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Rout, M., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2010) Proteins 78: 1992-1998

Released	2009-12-22
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Nucleoporin NUP145 (protein)
Unique Ligands	EDO

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3KFO \| pdb_00003kfo	Download File View File

Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae

Sampathkumar, P., Bonanno, J.B., Miller, S., Bain, K., Dickey, M., Gheyi, T., Almo, S.C., Rout, M., Sali, A., Phillips, J., Pieper, U., Fernandez-Martinez, J., Franke, J.D., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2011) Proteins 79: 1672-1677

Released	2010-01-26
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Nucleoporin NUP133 (protein)
Unique Ligands	GOL

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3NF5 \| pdb_00003nf5	Download File View File

Crystal structure of the C-terminal domain of nuclear pore complex component NUP116 from Candida glabrata

Sampathkumar, P., Manglicmot, D., Bain, K., Gilmore, J., Gheyi, T., Rout, M., Sali, A., Atwell, S., Thompson, D.A., Emtage, J.S., Wasserman, S., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2012) Proteins 80: 2110-2116

Released	2010-08-04
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Nakaseomyces glabratus
Macromolecule	Nucleoporin NUP116 (protein)
Unique Ligands	GOL

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4V47 \| pdb_00004v47	Download File View File

Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome

Gao, H., Sengupta, J., Valle, M., Korostelev, A., Eswar, N., Stagg, S.M., Van Roey, P., Agrawal, R.K., Harvey, S.T., Sali, A., Chapman, M.S., Frank, J.

(2003) Cell 113: 789-801

Released	2014-07-09
Method	ELECTRON MICROSCOPY 12.3 Å
Organisms	Escherichia coli
Macromolecule	Unique protein chains: 43 Unique nucleic acid chains: 3

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4V48 \| pdb_00004v48	Download File View File

Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome

Gao, H., Sengupta, J., Valle, M., Korostelev, A., Eswar, N., Stagg, S.M., Van Roey, P., Agrawal, R.K., Harvey, S.T., Sali, A., Chapman, M.S., Frank, J.

(2003) Cell 113: 789-801

Released	2014-07-09
Method	ELECTRON MICROSCOPY 11.5 Å
Organisms	Escherichia coli
Macromolecule	Unique protein chains: 44 Unique nucleic acid chains: 4

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4V7H \| pdb_00004v7h	Download File View File

Structure of the 80S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution

Taylor, D.J., Devkota, B., Huang, A.D., Topf, M., Narayanan, E., Sali, A., Harvey, S.C., Frank, J.

(2009) Structure 17: 1591-1604

Released	2014-07-09
Method	ELECTRON MICROSCOPY 8.9 Å
Organisms	Thermomyces lanuginosus
Macromolecule	Unique protein chains: 48 Unique nucleic acid chains: 5

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5ER2 \| pdb_00005er2	Download File View File

High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme

Sali, A., Veerapandian, B., Cooper, J.B., Foundling, S.I., Hoover, D.J., Blundell, T.L.

(1989) EMBO J 8: 2179-2188

Released	1991-04-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Cryphonectria parasitica
Macromolecule	ENDOTHIAPEPSIN (protein)
Unique Ligands	0EK

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5FLZ \| pdb_00005flz	Download File View File

Cryo-EM structure of gamma-TuSC oligomers in a closed conformation

Greenberg, C.H., Kollman, J., Zelter, A., Johnson, R., MacCoss, M.J., Davis, T.N., Agard, D.A., Sali, A.

(2016) J Struct Biol 194: 303

Released	2016-01-13
Method	ELECTRON MICROSCOPY 6.9 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	SPINDLE POLE BODY COMPONENT 110 (protein) SPINDLE POLE BODY COMPONENT SPC97 (protein) SPINDLE POLE BODY COMPONENT SPC98 (protein) TUBULIN GAMMA CHAIN (protein)

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5FM1 \| pdb_00005fm1	Download File View File

Structure of gamma-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure

Greenberg, C.H., Kollman, J., Zelter, A., Johnson, R., MacCoss, M.J., Davis, T.N., Agard, D.A., Sali, A.

(2016) J Struct Biol 194: 303

Released	2016-02-03
Method	ELECTRON MICROSCOPY 8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	SPINDLE POLE BODY COMPONENT 110 (protein) SPINDLE POLE BODY COMPONENT SPC97 (protein) SPINDLE POLE BODY COMPONENT SPC98 (protein) TUBULIN GAMMA CHAIN (protein)

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6DRD \| pdb_00006drd	Download File View File

RNA Pol II(G)

Yu, X., Jishage, M., Shi, Y., Ganesan, S., Sali, A., Chait, B.T., Asturias, F., Roeder, R.G.

(2018) Nat Struct Mol Biol 25: 859-867

Released	2019-06-12
Method	ELECTRON MICROSCOPY 3.9 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 13
Unique Ligands	ZN

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6XMJ \| pdb_00006xmj	Download File View File

Human 20S proteasome bound to an engineered 11S (PA26) activator

de la Pena, A.H., Opoku-Nsiah, K.A., Williams, S.K., Chopra, N., Sali, A., Gestwicki, J.E., Lander, G.C.

(2022) Nat Commun 13: 1226-1226

Released	2020-07-22
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Homo sapiens Trypanosoma brucei
Macromolecule	Unique protein chains: 15

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7M2W \| pdb_00007m2w	Download File View File

Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS)

Brilot, A.F., Lyon, A.S., Zelter, A., Viswanath, S., Maxwell, A., MacCoss, M.J., Muller, E.G., Sali, A., Davis, T.N., Agard, D.A.

(2021) Elife 10:

Released	2021-05-12
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Spindle pole body component 110 (protein) Spindle pole body component SPC97 (protein) Spindle pole body component SPC98 (protein) Tubulin gamma chain (protein)
Unique Ligands	GTP

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7M2X \| pdb_00007m2x	Download File View File

Open conformation of the Yeast wild-type gamma-TuRC

Brilot, A.F., Lyon, A.S., Zelter, A., Viswanath, S., Maxwell, A., MacCoss, M.J., Muller, E.G., Sali, A., Davis, T.N., Agard, D.A.

(2021) Elife 10:

Released	2021-05-12
Method	ELECTRON MICROSCOPY 3.6 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Spindle pole body component 110 (protein) Spindle pole body component SPC97 (protein) Spindle pole body component SPC98 (protein) Tubulin gamma chain (protein)
Unique Ligands	GDP

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1A5T | pdb_00001a5t

1BO4 | pdb_00001bo4

1CMO | pdb_00001cmo

1FI4 | pdb_00001fi4

1G61 | pdb_00001g61

1G62 | pdb_00001g62

1I9A | pdb_00001i9a

2GDQ | pdb_00002gdq

2GGE | pdb_00002gge

3B5U | pdb_00003b5u

3B63 | pdb_00003b63

3KEP | pdb_00003kep

3KES | pdb_00003kes

3KFO | pdb_00003kfo

3NF5 | pdb_00003nf5

4V47 | pdb_00004v47

4V48 | pdb_00004v48

4V7H | pdb_00004v7h

5ER2 | pdb_00005er2

5FLZ | pdb_00005flz

5FM1 | pdb_00005fm1

6DRD | pdb_00006drd

6XMJ | pdb_00006xmj

7M2W | pdb_00007m2w

7M2X | pdb_00007m2x