RCSB PDB: Search

1PZE \| pdb_00001pze	Download File View File

T.gondii LDH1 apo form

Kavanagh, K.L., Elling, R.A., Wilson, D.K.

(2004) Biochemistry 43: 879-889

Released	2004-02-24
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	lactate dehydrogenase (protein)

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1PZG \| pdb_00001pzg	Download File View File

T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms

Kavanagh, K.L., Elling, R.A., Wilson, D.K.

(2004) Biochemistry 43: 879-889

Released	2004-02-24
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	lactate dehydrogenase (protein)
Unique Ligands	A3D, SO4

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1PZH \| pdb_00001pzh	Download File View File

T.gondii LDH1 ternary complex with NAD and oxalate

Kavanagh, K.L., Elling, R.A., Wilson, D.K.

(2004) Biochemistry 43: 879-889

Released	2004-02-24
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	lactate dehydrogenase (protein)
Unique Ligands	NAD, OXL

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2JKS \| pdb_00002jks	Download File View File

Crystal structure of the the bradyzoite specific antigen BSR4 from toxoplasma gondii.

Boulanger, M.J., Grigg, M.E., Bruic, E., Grujic, O.

(2009) J Biological Chem 284: 9192

Released	2009-02-03
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	BRADYZOITE SURFACE ANTIGEN BSR4 (protein)
Unique Ligands	ZN

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3HZT \| pdb_00003hzt	Download File View File

Crystal structure of Toxoplasma gondii CDPK3, TGME49_105860

Wernimont, A.K., Artz, J.D., Finnerty, P., Wasney, G., Allali-Hassani, A., Vedadi, M., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)

(2010) Nat Struct Mol Biol 17: 596-601

Released	2009-07-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Calcium-dependent protein kinase 3 (protein)
Unique Ligands	GOL, J60, MG

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3IS5 \| pdb_00003is5	Download File View File

Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720

Wernimont, A.K., Artz, J.D., Senisterra, G., MacKenzie, F., Hutchinson, A., Kozieradzki, I., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Structural Genomics Consortium (SGC)

To be published

Released	2009-10-20
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Calcium-dependent protein kinase (protein)
Unique Ligands	ANP, CA, GOL, MG

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3OBK \| pdb_00003obk	Download File View File

Crystal structure of delta-aminolevulinic acid dehydratase (porphobilinogen synthase) from toxoplasma gondii ME49 in complex with the reaction product porphobilinogen

Seattle Structural Genomics Center for Infectious Disease (SSGCID)

(2011) J Biological Chem 286: 15298-15307

Released	2010-09-15
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Delta-aminolevulinic acid dehydratase (protein)
Unique Ligands	CL, EDO, MG, PBG

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3OTR \| pdb_00003otr	Download File View File

2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii

Minasov, G., Ruan, J., Shuvalova, L., Halavaty, A., Ngo, H., Tomavo, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) Acta Crystallogr D Biol Crystallogr 71: 417-426

Released	2010-09-22
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Enolase (protein)
Unique Ligands	CL, SO4

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3QYQ \| pdb_00003qyq	Download File View File

1.8 Angstrom resolution crystal structure of a putative deoxyribose-phosphate aldolase from Toxoplasma gondii ME49

Halavaty, A.S., Ruan, J., Minasov, G., Shuvalova, L., Ueno, A., Igarashi, M., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2015) J Mol Biology 427: 840-852

Released	2011-03-30
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Deoxyribose-phosphate aldolase, putative (protein)
Unique Ligands	SO4
Unique branched monosaccharides	FRU, GLC

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3RP9 \| pdb_00003rp9	Download File View File

Crystal Structure of the apo MapK from Toxoplasma Gondii, 25.m01780 or TGME49_007820

Wernimont, A.K., Crombet, L., Pizarro, J.C., Crowther, G.J., Van Voorhis, W.C., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Lin, Y.H., Structural Genomics Consortium (SGC)

To be published

Released	2011-06-15
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Mitogen-activated protein kinase (protein)
Unique Ligands	SO4

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4CHJ \| pdb_00004chj	Download File View File

Structure of Inner Membrane Complex (IMC) Sub-compartment Protein 3 (ISP3) from Toxoplasma gondii

Tonkin, M.L., Beck, J.R., Bradley, P.J., Boulanger, M.J.

(2014) J Biological Chem 289: 13962

Released	2014-04-09
Method	X-RAY DIFFRACTION 2.32 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	IMC SUB-COMPARTMENT PROTEIN ISP3 (protein)

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4CHM \| pdb_00004chm	Download File View File

Structure of Inner Membrane Complex (IMC) Sub-compartment Protein 1 (ISP1) from Toxoplasma gondii

Tonkin, M.L., Beck, J.R., Bradley, P.J., Boulanger, M.J.

(2014) J Biological Chem 289: 13962

Released	2014-04-09
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	IMC SUB-COMPARTMENT PROTEIN ISP1 (protein)
Unique Ligands	SO4

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4IR8 \| pdb_00004ir8	Download File View File

1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii

Minasov, G., Ruan, J., Wawrzak, Z., Halavaty, A., Shuvalova, L., Harb, O.S., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2013-01-23
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Sedoheptulose-1,7 bisphosphatase, putative (protein)
Unique Ligands	ACT, PEG

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4NML \| pdb_00004nml	Download File View File

2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid

Halavaty, A.S., Dubrovska, I., Flores, K., Shanmugam, D., Shuvalova, L., Roos, D., Ruan, J., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2018) Front Cell Infect Microbiol 8: 352-352

Released	2013-12-04
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Ribulose 5-phosphate isomerase (protein)
Unique Ligands	CL, MLT

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4NOG \| pdb_00004nog	Download File View File

Crystal structure of a putative ornithine aminotransferase from Toxoplasma gondii ME49 in complex with pyrodoxal-5'-phosphate

Filippova, E.V., Halavaty, A., Ruan, J., Shuvalova, L., Flores, K., Dubrovska, I., Ngo, H., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID)

(2018) Front Cell Infect Microbiol 8: 352-352

Released	2013-12-04
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Putative ornithine aminotransferase, mitochondrial (protein)
Unique Ligands	ACT, BME, BTB, PEG, PLP

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4O0N \| pdb_00004o0n	Download File View File

2.4 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii.

Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2018) Front Cell Infect Microbiol 8: 352-352

Released	2013-12-25
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Nucleoside diphosphate kinase (protein)
Unique Ligands	SO4

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4ODI \| pdb_00004odi	Download File View File

2.6 Angstrom Crystal Structure of Putative Phosphoglycerate Mutase 1 from Toxoplasma gondii

Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2018) Front Cell Infect Microbiol 8: 352-352

Released	2014-01-22
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Phosphoglycerate mutase PGMII (protein)
Unique Ligands	NA

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4YIV \| pdb_00004yiv	Download File View File

Crystal structure of engineered TgAMA1 lacking the DII loop

Parker, M.L., Boulanger, M.J.

(2015) PLoS One 10: e0126206-e0126206

Released	2015-05-20
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Apical membrane antigen AMA1 (protein)
Unique Ligands	CD, CL, CO, GOL, NAG

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4YIZ \| pdb_00004yiz	Download File View File

Crystal structure of engineered TgAMA1 lacking the DII loop in complex with an Eimeria tenella RON2D3 peptide

Parker, M.L., Boulanger, M.J.

(2015) PLoS One 10: e0126206-e0126206

Released	2015-05-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Eimeria tenella Toxoplasma gondii ME49
Macromolecule	Apical membrane antigen AMA1 (protein) Rhoptry neck protein 2, putative (protein)
Unique Ligands	A2G, NAG, SO4

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4ZLV \| pdb_00004zlv	Download File View File

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with the Schiff base between PLP and Lys286

Filippova, E.V., Minasov, G., Flores, K., Van Le, H., Silverman, R.B., McLeod, R., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2015-05-20
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Ornithine aminotransferase, mitochondrial, putative (protein)
Unique Ligands	PEG, PLP, SO4

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4ZWM \| pdb_00004zwm	Download File View File

2.3 A resolution crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49

Filippova, E.V., Minasov, G., Flores, K., Van Le, H., Silverman, R.B., McLeod, R., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2015-06-03
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Ornithine aminotransferase, mitochondrial, putative (protein)
Unique Ligands	PLP, SO4

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5BXI \| pdb_00005bxi	Download File View File

1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site

Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

(2018) Front Cell Infect Microbiol 8: 352-352

Released	2015-06-24
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Nucleoside diphosphate kinase (protein)
Unique Ligands	BCT, PEG

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5DJ9 \| pdb_00005dj9	Download File View File

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine

Filippova, E.V., Minasov, G., Flores, K., Le, H.V., Silverman, R.B., McLeod, R.L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2016-10-05
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Ornithine aminotransferase, mitochondrial (protein)
Unique Ligands	BTB, PXG, SO4, TRS

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5E3K \| pdb_00005e3k	Download File View File

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid

Filippova, E.V., Minasov, G., Flores, K., Le, H.V., Silverman, R.B., McLeod, R.L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2016-10-26
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Aminotransferase (protein)
Unique Ligands	5JV, CO3, PEG, SO4

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5EAV \| pdb_00005eav	Download File View File

Unliganded structure of the ornithine aminotransferase from Toxoplasma gondii

Filippova, E.V., Minasov, G., Flores, K., Le, H.V., Silverman, R.B., McLeod, R.L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2015-11-18
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Ornithine aminotransferase, mitochondrial, putative (protein)
Unique Ligands	PEG, SO4

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1PZE | pdb_00001pze

1PZG | pdb_00001pzg

1PZH | pdb_00001pzh

2JKS | pdb_00002jks

3HZT | pdb_00003hzt

3IS5 | pdb_00003is5

3OBK | pdb_00003obk

3OTR | pdb_00003otr

3QYQ | pdb_00003qyq

3RP9 | pdb_00003rp9

4CHJ | pdb_00004chj

4CHM | pdb_00004chm

4IR8 | pdb_00004ir8

4NML | pdb_00004nml

4NOG | pdb_00004nog

4O0N | pdb_00004o0n

4ODI | pdb_00004odi

4YIV | pdb_00004yiv

4YIZ | pdb_00004yiz

4ZLV | pdb_00004zlv

4ZWM | pdb_00004zwm

5BXI | pdb_00005bxi

5DJ9 | pdb_00005dj9

5E3K | pdb_00005e3k

5EAV | pdb_00005eav