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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Sprinzl, M."

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Search Summary

This query matches 14 Structures.

Refinements

Structure Determination Methodology

experimental (14)

Scientific Name of Source Organism

	Homo sapiens (9)
	Escherichia coli (4)
	Escherichia coli K-12 (1)
	actinomycete 095-35 (1)

Taxonomy

	Eukaryota (9)
	Bacteria (6)

Experimental Method

X-RAY DIFFRACTION (14)

Polymer Entity Type

Protein (14)

Refinement Resolution (Å)

	1.5 - 2.0 (3)
	2.0 - 2.5 (9)
	2.5 - 3.0 (2)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (6)
	2010 - 2014 (3)
	2015 - 2019 (3)
	2020 - 2024 (1)

Enzyme Classification Name

	Transferases (5)
	Hydrolases (9)

Symmetry Type

	Asymmetric (9)
	Dihedral (5)

SCOP Classification

	All alpha proteins (5)
	Alpha and beta proteins (a+b) (6)
	All beta proteins (3)
	Alpha and beta proteins (a/b) (3)

AllSelected

1 to 14 of 14 Structures

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1CPU \| pdb_00001cpu	Download File View File

SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT

Brayer, G.D., Sidhu, G., Maurus, R., Rydberg, E.H., Braun, C., Wang, Y., Nguyen, N.T., Overall, C.M., Withers, S.G.

(2000) Biochemistry 39: 4778-4791

Released	1999-06-14
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (ALPHA-AMYLASE) (protein)
Unique Ligands	CA, CL, HMC, NAG
Unique branched monosaccharides	AGL, GLC

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1NXE \| pdb_00001nxe	Download File View File

A Novel NADH Allosteric Regulator Site is Found on the Surface of the Hexameric Type II Phe383Ala Variant of Citrate Synthase

Maurus, R., Nguyen, N.T., Stokell, D.J., Ayed, A., Hultin, P.G., Duckworth, H.W., Brayer, G.D.

(2003) Biochemistry 42: 5555-5565

Released	2003-04-08
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	Citrate synthase (protein)
Unique Ligands	SO4

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1NXG \| pdb_00001nxg	Download File View File

The F383A variant of type II Citrate Synthase complexed with NADH

Maurus, R., Nguyen, N.T., Stokell, D.J., Ayed, A., Hultin, P.G., Duckworth, H.W., Brayer, G.D.

(2003) Biochemistry 42: 5555-5565

Released	2003-04-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	Citrate synthase (protein)
Unique Ligands	NAI, SO4

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1OWB \| pdb_00001owb	Download File View File

Three Dimensional Structure Analysis Of The Variant R109L NADH Complex of Type II Citrate Synthase From E. Coli

Stokell, D.J., Donald, L.J., Maurus, R., Nguyen, N.T., Sadler, G., Choudhary, K., Hultin, P.G., Brayer, G.D., Duckworth, H.W.

(2003) J Biological Chem 278: 35435-35443

Released	2004-05-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli
Macromolecule	Citrate synthase (protein)
Unique Ligands	NAD, SO4

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1OWC \| pdb_00001owc	Download File View File

Three Dimensional Structure Analysis Of The R109L Variant of the Type II Citrate Synthase From E. Coli

Stokell, D.J., Donald, L.J., Maurus, R., Nguyen, N.T., Sadler, G., Choudhary, K., Hultin, P.G., Brayer, G.D., Duckworth, H.W.

(2003) J Biological Chem 278: 35435-35443

Released	2004-05-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli
Macromolecule	Citrate synthase (protein)
Unique Ligands	SO4

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2CPU \| pdb_00002cpu	Download File View File

SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT

Brayer, G.D., Sidhu, G., Maurus, R., Rydberg, E.H., Braun, C., Wang, Y., Nguyen, N.T., Overall, C.M., Withers, S.G.

(2000) Biochemistry 39: 4778-4791

Released	2001-06-30
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	ALPHA-AMYLASE (protein)
Unique Ligands	CA, CL

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3CPU \| pdb_00003cpu	Download File View File

SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT

Brayer, G.D., Sidhu, G., Maurus, R., Rydberg, E.H., Braun, C., Wang, Y., Nguyen, N.T., Overall, C.M., Withers, S.G.

(2000) Biochemistry 39: 4778-4791

Released	2001-06-30
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Pancreatic alpha-amylase (protein)
Unique Ligands	CA, CL
Unique branched monosaccharides	GLC

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4G6B \| pdb_00004g6b	Download File View File

Three dimensional structure analysis of the type II citrate synthase from e.coli

Nguyen, N.T., Maurus, R., Stokell, D.J., Ayed, A., Duckworth, H.W., Brayer, G.D.

(2001) Biochemistry 40: 13177

Released	2013-11-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli K-12
Macromolecule	Citrate synthase (protein)
Unique Ligands	SO4

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4N79 \| pdb_00004n79	Download File View File

Structure of Cathepsin K-dermatan sulfate complex

Aguda, A.H., Nguyen, N.T., Bromme, D., Brayer, G.D.

(2014) Proc Natl Acad Sci U S A 111: 17474-17479

Released	2014-11-26
Method	X-RAY DIFFRACTION 2.62 Å
Organisms	Homo sapiens
Macromolecule	Cathepsin K (protein)
Unique branched monosaccharides	ASG, IDR

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4N8W \| pdb_00004n8w	Download File View File

cathepsin K - chondroitin sulfate complex

Aguda, A.H., Nguyen, N.T., Bromme, D., Brayer, G.D.

(2014) Proc Natl Acad Sci U S A 111: 17474-17479

Released	2014-11-26
Method	X-RAY DIFFRACTION 2.02 Å
Organisms	Homo sapiens
Macromolecule	Cathepsin K (protein)
Unique branched monosaccharides	ASG, BDP

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4YV8 \| pdb_00004yv8	Download File View File

Crystal structure of cathepsin K bound to the covalent inhibitor lichostatinal

Aguda, A.H., Nguyen, N.T., Bromme, D., Brayer, G.D.

(2016) J Nat Prod 79: 1962-1970

Released	2016-05-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens actinomycete 095-35
Macromolecule	Cathepsin K (protein) Lichostatinal (protein)
Unique Ligands	SO4