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235,183 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Structural Genomics of Pathogenic Protozoa Consortium (SGPP)"

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Search Summary

This query matches 75 Structures.

Refinements

Structure Determination Methodology

experimental (75)

Scientific Name of Source Organism

	Leishmania major (19)
	Trypanosoma brucei (10)
	Plasmodium falciparum 3D7 (8)
	Plasmodium falciparum (7)
	Plasmodium vivax (6)
	Trypanosoma cruzi (6)
	Leishmania major strain Friedlin (4)
	Trypanosoma cruzi strain CL Brener (3)
	Leishmania braziliensis MHOM/BR/75/M2904 (2)
	Leishmania donovani (2)

More...

Taxonomy

	Eukaryota (74)
	Eukaryota (eukaryotes) (4)

Experimental Method

X-RAY DIFFRACTION (75)

Polymer Entity Type

Protein (75)

Refinement Resolution (Å)

	1.0 - 1.5 (3)
	1.5 - 2.0 (27)
	2.0 - 2.5 (30)
	2.5 - 3.0 (13)
	3.0 - 3.5 (1)
	3.5 - 4.0 (1)

Release Date

	2000 - 2004 (18)
	2005 - 2009 (49)
	2010 - 2014 (5)
	2020 - 2024 (2)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (15)
	Hydrolases (10)
	Oxidoreductases (10)
	Isomerases (7)
	Lyases (6)
	Ligases (1)

Symmetry Type

	Cyclic (37)
	Asymmetric (36)
	Dihedral (9)
	Octahedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (34)
	Alpha and beta proteins (a+b) (15)
	Artifacts (19)
	All beta proteins (10)
	All alpha proteins (3)
	Designed proteins (1)

AllSelected

1 to 25 of 75 Structures

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1R75 \| pdb_00001r75	Download File View File

Leishmania major hypothetical protein

Han, G.W., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2003-12-02
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Leishmania major
Macromolecule	hypothetical protein (protein)
Unique Ligands	GOL

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1SQ6 \| pdb_00001sq6	Download File View File

Plasmodium falciparum homolog of Uridine phosphorylase/Purine nucleoside phosphorylase

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

(2005) Acta Crystallogr D Biol Crystallogr 61: 1245-1254

Released	2004-04-06
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Plasmodium falciparum 3D7
Macromolecule	uridine phosphorylase, putative (protein)
Unique Ligands	SO4

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1SVV \| pdb_00001svv	Download File View File

Initial Stuctural Analysis of Leishmania major Threonine Aldolase

Hol, W.G.J., Robien, M.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-08-17
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Leishmania major
Macromolecule	THREONINE ALDOLASE (protein)
Unique Ligands	UNL

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1SYR \| pdb_00001syr	Download File View File

Initial Structural Analysis of Plasmodium falciparum thioredoxin

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-04-13
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Plasmodium falciparum 3D7
Macromolecule	thioredoxin (protein)

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1TC5 \| pdb_00001tc5	Download File View File

Structural Analysis of a probable eukaryotic D-amino acid tRNA deacylase

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-06-08
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Leishmania major
Macromolecule	Probable eukaryotic D-amino acid tRNA deacylase, LMAJ005534AAA (protein)

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1TQX \| pdb_00001tqx	Download File View File

Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum

Caruthers, J., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

(2006) Proteins 62: 338-342

Released	2004-12-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Plasmodium falciparum 3D7
Macromolecule	D-ribulose-5-phosphate 3-epimerase, putative (protein)
Unique Ligands	SO4, ZN

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1VJQ \| pdb_00001vjq	Download File View File

Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.

Merritt, E.A., Baker, D., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-03-30
Method	X-RAY DIFFRACTION 2.098 Å
Macromolecule	designed protein (protein)

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1VJU \| pdb_00001vju	Download File View File

Coproporphyrinogen III oxidase from Leishmania major

Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-04-13
Method	X-RAY DIFFRACTION 1.401 Å
Organisms	Leishmania major
Macromolecule	Coproporphyrinogen III oxidase (protein)

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1X6O \| pdb_00001x6o	Download File View File

Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a

Bosch, J., Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-08-24
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Leishmania braziliensis
Macromolecule	eukaryotic initiation factor 5a (protein)
Unique Ligands	PEG

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1X9G \| pdb_00001x9g	Download File View File

PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA DONOVANI

Caruthers, J., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

(2005) Protein Sci 14: 2887-2894

Released	2004-09-07
Method	X-RAY DIFFRACTION 2.41 Å
Organisms	Leishmania donovani
Macromolecule	PUTATIVE MAR1 (protein)

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1XIQ \| pdb_00001xiq	Download File View File

Plasmodium falciparum Nucleoside diphosphate kinase B

Robien, M.A., Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-10-12
Method	X-RAY DIFFRACTION 3.05 Å
Organisms	Plasmodium falciparum 3D7
Macromolecule	Nucleoside diphosphate kinase B (protein)

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1XN4 \| pdb_00001xn4	Download File View File

PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA MAJOR

Caruthers, J., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

(2005) Protein Sci 14: 2887-2894

Released	2004-10-12
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Leishmania major
Macromolecule	ribonuclease MAR1 (protein)

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1XO7 \| pdb_00001xo7	Download File View File

Crystal structure of cyclophilin from Trypanosoma cruzi

Caruthers, J.M., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-12-21
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Trypanosoma cruzi
Macromolecule	cyclophilin (protein)

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1XQ7 \| pdb_00001xq7	Download File View File

Cyclophilin from Trypanosoma cruzi bound to cyclosporin A

Caruthers, J.M., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-12-21
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Tolypocladium inflatum Trypanosoma cruzi
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (protein)

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1XQ9 \| pdb_00001xq9	Download File View File

Structure of Phosphoglycerate Mutase from Plasmodium falciparum at 2.6 Resolution

Caruthers, J.M., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-12-21
Method	X-RAY DIFFRACTION 2.58 Å
Organisms	Plasmodium falciparum
Macromolecule	phosphoglycerate mutase (protein)
Unique Ligands	SCN

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1XTD \| pdb_00001xtd	Download File View File

Structural Analysis of Leishmania mexicana eukaryotic initiation factor 5a

Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-10-26
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Leishmania mexicana
Macromolecule	eukaryotic initiation factor 5a (protein)

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1XTP \| pdb_00001xtp	Download File View File

Structural Analysis of Leishmania major LMAJ004091AAA, a SAM-dependent methyltransferase of the DUF858/Pfam05891 family

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-11-09
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Leishmania major strain Friedlin
Macromolecule	LMAJ004091AAA (protein)
Unique Ligands	SAI

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1Y13 \| pdb_00001y13	Download File View File

Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)

Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2005-01-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Plasmodium falciparum
Macromolecule	6-pyruvoyl tetrahydropterin synthase (protein)
Unique Ligands	BIO, ZN

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1Y1X \| pdb_00001y1x	Download File View File

Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-12-07
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Leishmania major strain Friedlin
Macromolecule	Leishmania Major Homolog of Programmed Cell Death 6 Protein (protein)
Unique Ligands	CA, SO4

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1Y63 \| pdb_00001y63	Download File View File

Initial crystal structural analysis of a probable kinase from Leishmania major Friedlin

Robien, M.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2005-01-04
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Leishmania major strain Friedlin
Macromolecule	Lmaj004144AAA protein (protein)
Unique Ligands	ADP, BR, MN, NA