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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Swanson, R.V."

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Search Summary

This query matches 22 Structures.

Refinements

Structure Determination Methodology

experimental (22)

Scientific Name of Source Organism

	Homo sapiens (13)
	Haemophilus influenzae (4)
	Escherichia coli (2)
	Staphylococcus aureus (1)
	Thermosphaera aggregans (1)
	Thermotoga maritima (1)

Taxonomy

	Eukaryota (13)
	Bacteria (8)
	Archaea (1)

Experimental Method

	X-RAY DIFFRACTION (21)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (22)

Refinement Resolution (Å)

	1.5 - 2.0 (10)
	2.0 - 2.5 (8)
	2.5 - 3.0 (3)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (15)
	2005 - 2009 (2)
	2010 - 2014 (4)

Enzyme Classification Name

	Transferases (8)
	Hydrolases (4)
	Oxidoreductases (5)
	Ligases (2)

Symmetry Type

	Asymmetric (17)
	Cyclic (7)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (11)
	Alpha and beta proteins (a+b) (7)
	All alpha proteins (3)
	All beta proteins (1)
	Artifacts (1)

AllSelected

1 to 22 of 22 Structures

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1K0S \| pdb_00001k0s	Download File View File

Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima

Griswold, I.J., Zhou, H., Swanson, R.V., Simon, M.I., Dahlquist, F.W.

(2002) Nat Struct Biol 9: 121-125

Released	2002-02-06
Method	SOLUTION NMR
Organisms	Thermotoga maritima
Macromolecule	CHEMOTAXIS PROTEIN CHEW (protein)

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1MP8 \| pdb_00001mp8	Download File View File

Crystal structure of Focal Adhesion Kinase (FAK)

Nowakowski, J., Cronin, C.N., McRee, D.E., Knuth, M.W., Nelson, C.G., Pavletich, N.P., Rodgers, J., Sang, B.-C., Scheibe, D.N., Swanson, R.V., Thompson, D.A.

(2002) Structure 10: 1659-1667

Released	2003-09-16
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	focal adhesion kinase 1 (protein)
Unique Ligands	ADP

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1MQ4 \| pdb_00001mq4	Download File View File

Crystal Structure of Aurora-A Protein Kinase

Nowakowski, J., Cronin, C.N., McRee, D.E., Knuth, M.W., Nelson, C., Pavletich, N.P., Rodgers, J., Sang, B.-C., Scheibe, D.N., Swanson, R.V., Thompson, D.A.

(2002) Structure 10: 1659-1667

Released	2003-09-16
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	AURORA-RELATED KINASE 1 (protein)
Unique Ligands	ADP, MG, PO4

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1MQB \| pdb_00001mqb	Download File View File

Crystal Structure of Ephrin A2 (ephA2) Receptor Protein Kinase

Nowakowski, J., Cronin, C.N., McRee, D.E., Knuth, M.W., Nelson, C., Pavletich, N., Rogers, J., Sang, B.C., Scheibe, D.N., Swanson, R.V., Thompson, D.A.

(2003) Structure 10: 1659-1667

Released	2003-09-16
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Ephrin type-A receptor 2 (protein)
Unique Ligands	ANP

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1P31 \| pdb_00001p31	Download File View File

Crystal Structure of UDP-N-acetylmuramic acid:L-alanine Ligase (MurC) from Haemophilus influenzae

Mol, C.D., Brooun, A., Dougan, D.R., Hilgers, M.T., Tari, L.W., Wijnands, R.A., Knuth, M.W., McRee, D.E., Swanson, R.V.

(2003) J Bacteriol 185: 4152-4162

Released	2003-07-15
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Haemophilus influenzae
Macromolecule	UDP-N-acetylmuramate--alanine ligase (protein)
Unique Ligands	EPU, MG

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1P3D \| pdb_00001p3d	Download File View File

Crystal Structure of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) in Complex with UMA and ANP.

Mol, C.D., Brooun, A., Dougan, D.R., Hilgers, M.T., Tari, L.W., Wijnands, R.A., Knuth, M.W., McRee, D.E., Swanson, R.V.

(2003) J Bacteriol 185: 4152-4162

Released	2003-07-15
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Haemophilus influenzae
Macromolecule	UDP-N-acetylmuramate--alanine ligase (protein)
Unique Ligands	ANP, MN, UMA

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1P74 \| pdb_00001p74	Download File View File

CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE

Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E.

(2003) J Bacteriol 185: 4144-4151

Released	2003-08-12
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Haemophilus influenzae
Macromolecule	Shikimate 5-dehydrogenase (protein)

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1P77 \| pdb_00001p77	Download File View File

CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE

Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E.

(2003) J Bacteriol 185: 4144-4151

Released	2003-08-12
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Haemophilus influenzae
Macromolecule	Shikimate 5-dehydrogenase (protein)
Unique Ligands	ACT, ATR

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1QVB \| pdb_00001qvb	Download File View File

CRYSTAL STRUCTURE OF THE BETA-GLYCOSIDASE FROM THE HYPERTHERMOPHILE THERMOSPHAERA AGGREGANS

Chi, Y.-I., Martinez-Cruz, L.A., Swanson, R.V., Robertson, D.E., Kim, S.-H.

(1999) FEBS Lett 445: 375-383

Released	1999-07-13
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Thermosphaera aggregans
Macromolecule	BETA-GLYCOSIDASE (protein)

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1RQI \| pdb_00001rqi	Download File View File

Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate

Hosfield, D.J., Zhang, Y., Dougan, D.R., Brooun, A., Tari, L.W., Swanson, R.V., Finn, J.

(2004) J Biological Chem 279: 8526-8529

Released	2004-03-02
Method	X-RAY DIFFRACTION 2.42 Å
Organisms	Escherichia coli
Macromolecule	Geranyltranstransferase (protein)
Unique Ligands	DPO, DST, IPR, MG

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1RQJ \| pdb_00001rqj	Download File View File

Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Risedronate

Hosfield, D.J., Zhang, Y., Dougan, D.R., Brooun, A., Tari, L.W., Swanson, R.V., Finn, J.

(2004) J Biological Chem 279: 8526-8529

Released	2004-03-02
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Escherichia coli
Macromolecule	Geranyltranstransferase (protein)
Unique Ligands	IPE, MG, RIS

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1RTR \| pdb_00001rtr	Download File View File

Crystal Structure of S. Aureus Farnesyl Pyrophosphate Synthase

Hosfield, D.J., Zhang, Y., Dougan, D.R., Brooun, A., Tari, L.W., Swanson, R.V., Finn, J.

(2004) J Mol Biology 279: 8526-8529

Released	2004-03-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Staphylococcus aureus
Macromolecule	geranyltranstransferase (protein)

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1T64 \| pdb_00001t64	Download File View File

Crystal Structure of human HDAC8 complexed with Trichostatin A

Somoza, J.R., Skene, R.J., Katz, B.A., Mol, C., Ho, J.D., Jennings, A.J., Luong, C., Arvai, A., Buggy, J.J., Chi, E., Tang, J., Sang, B.-C., Verner, E., Wynands, R., Leahy, E.M., Dougan, D.R., Snell, G., Navre, M., Knuth, M.W., Swanson, R.V., McRee, D.E., Tari, L.W.

(2004) Structure 12: 1325-1334

Released	2004-07-27
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Histone deacetylase 8 (protein)
Unique Ligands	CA, NA, TSN, ZN

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1T67 \| pdb_00001t67	Download File View File

Crystal Structure of Human HDAC8 complexed with MS-344

(2004) Structure 12: 1325-1334

Released	2004-07-27
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens
Macromolecule	Histone deacetylase 8 (protein)
Unique Ligands	B3N, NA, ZN

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1T69 \| pdb_00001t69	Download File View File

Crystal Structure of human HDAC8 complexed with SAHA

(2004) Structure 12: 1325-1334

Released	2004-07-27
Method	X-RAY DIFFRACTION 2.91 Å
Organisms	Homo sapiens
Macromolecule	Histone deacetylase 8 (protein)
Unique Ligands	SHH, ZN

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1VKG \| pdb_00001vkg	Download File View File

Crystal Structure of Human HDAC8 complexed with CRA-19156

(2004) Structure 12: 1325-1334

Released	2004-07-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Histone deacetylase 8 (protein)
Unique Ligands	CRI, NA, ZN

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2NP8 \| pdb_00002np8	Download File View File

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Tari, L.W., Hoffman, I.D., Bensen, D.C., Hunter, M.J., Nix, J., Nelson, K.J., McRee, D.E., Swanson, R.V.

(2007) Bioorg Med Chem Lett 17: 688-691

Released	2006-12-26
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase 6 (protein)
Unique Ligands	CC3, SO4

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3HF6 \| pdb_00003hf6	Download File View File

Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE

Tari, L.W., Swanson, R.V., Hunter, M.J.

(2010) Bioorg Med Chem Lett 4: 19-26

Released	2009-11-24
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Tryptophan 5-hydroxylase 1 (protein)
Unique Ligands	FE, LX0

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3HF8 \| pdb_00003hf8	Download File View File

Crystal structure of human tryoptophan hydroxylase type 1 with bound LP-533401 and Fe

Tari, L.W., Swanson, R.V., Hunter, M.J.

(2010) Curr Chem Genomics 4: 19-26

Released	2010-04-21
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Tryptophan 5-hydroxylase 1 (protein)
Unique Ligands	FE, ML0

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3HFB \| pdb_00003hfb	Download File View File

Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193

Tari, L.W., Swanson, R.V., Hunter, M.J.

(2010) Curr Chem Genomics 4: 19-26

Released	2010-04-21
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Homo sapiens
Macromolecule	Tryptophan 5-hydroxylase 1 (protein)
Unique Ligands	FE, ML4

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3IPX \| pdb_00003ipx	Download File View File

X-Ray structure of Human Deoxycytidine Kinase in complex with ADP and an inhibitor

Tari, L.W., Swanson, R.V., Hunter, M., Hoffman, I., Stouch, T.R., Carson, K.G.

(2009) Bioorg Med Chem Lett 19: 6784-6787

Released	2010-08-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Deoxycytidine kinase (protein)
Unique Ligands	ADP, B86, MG

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3IPY \| pdb_00003ipy	Download File View File

X-Ray structure of Human Deoxycytidine Kinase in complex with an inhibitor

Tari, L.W., Swanson, R.V., Hunter, M., Hoffman, I., Stouch, T.R., Carson, K.G.

(2009) Bioorg Med Chem Lett 19: 6784-6787

Released	2010-08-18
Method	X-RAY DIFFRACTION 2.54 Å
Organisms	Homo sapiens
Macromolecule	Deoxycytidine kinase (protein)
Unique Ligands	B87, MLT

1 to 22 of 22 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1K0S | pdb_00001k0s

1MP8 | pdb_00001mp8

1MQ4 | pdb_00001mq4

1MQB | pdb_00001mqb

1P31 | pdb_00001p31

1P3D | pdb_00001p3d

1P74 | pdb_00001p74

1P77 | pdb_00001p77

1QVB | pdb_00001qvb

1RQI | pdb_00001rqi

1RQJ | pdb_00001rqj

1RTR | pdb_00001rtr

1T64 | pdb_00001t64

1T67 | pdb_00001t67

1T69 | pdb_00001t69

1VKG | pdb_00001vkg

2NP8 | pdb_00002np8

3HF6 | pdb_00003hf6

3HF8 | pdb_00003hf8

3HFB | pdb_00003hfb

3IPX | pdb_00003ipx

3IPY | pdb_00003ipy