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234,785 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "TB Structural Genomics Consortium (TBSGC)"

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Search Summary

This query matches 369 Structures.

Refinements

Structure Determination Methodology

experimental (369)

Scientific Name of Source Organism

	Mycobacterium tuberculosis (222)
	Mycobacterium tuberculosis H37Rv (124)
	Mycobacterium tuberculosis H37Ra (14)
	Mycolicibacterium smegmatis MC2 155 (4)
	Mycobacterium marinum M (1)
	Mycobacterium tuberculosis F11 (1)
	Mycobacterium tuberculosis variant bovis (1)
	Mycobacteroides abscessus ATCC 19977 (1)
	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (1)
	Tequatrovirus T4 (1)

Taxonomy

	Bacteria (367)
	Duplodnaviria (1)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (365)
	SOLUTION NMR (3)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

	Protein (369)
	DNA (5)
	RNA (1)

Refinement Resolution (Å)

	1.0 - 1.5 (14)
	1.5 - 2.0 (135)
	2.0 - 2.5 (143)
	2.5 - 3.0 (58)
	3.0 - 3.5 (14)
	3.5 - 4.0 (2)

Release Date

	1995 - 1999 (8)
	2000 - 2004 (105)
	2005 - 2009 (88)
	2010 - 2014 (88)
	2015 - 2019 (64)
	2020 - 2024 (16)

Enzyme Classification Name

	Transferases (127)
	Lyases (51)
	Oxidoreductases (48)
	Hydrolases (45)
	Isomerases (19)
	Ligases (22)
	Translocases (3)

Membrane Protein Annotation

OPM (6)

Symmetry Type

	Asymmetric (158)
	Cyclic (180)
	Dihedral (62)
	Octahedral (4)
	Tetrahedral (2)

SCOP Classification

	Alpha and beta proteins (a/b) (146)
	Alpha and beta proteins (a+b) (70)
	All beta proteins (38)
	Artifacts (45)
	All alpha proteins (21)
	Multi-domain proteins (alpha and beta) (5)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 369 Structures

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1BVR \| pdb_00001bvr	Download File View File

M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE

Rozwarski, D.A., Vilcheze, C., Sugantino, M., Bittman, R., Jacobs, W., TB Structural Genomics Consortium (TBSGC)

(1999) J Biological Chem 274: 15582-15589

Released	1999-09-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	PROTEIN (ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE) (protein)
Unique Ligands	NAD, THT

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1C3V \| pdb_00001c3v	Download File View File

DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC

Cirilli, M., Zheng, R., Scapin, G., Blanchard, J.S., TB Structural Genomics Consortium (TBSGC)

(2003) Biochemistry 42: 10644-10650

Released	2003-08-26
Method	X-RAY DIFFRACTION 2.39 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	DIHYDRODIPICOLINATE REDUCTASE (protein)
Unique Ligands	NDP, PDC, PG4

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1DQY \| pdb_00001dqy	Download File View File

CRYSTAL STRUCTURE OF ANTIGEN 85C FROM MYCOBACTERIUM TUBERCULOSIS WITH DIETHYL PHOSPHATE INHIBITOR

Ronning, D.R., Klabunde, T., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 141-146

Released	2000-07-12
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	PROTEIN (ANTIGEN 85-C) (protein)
Unique Ligands	DEP, MRD

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1DQZ \| pdb_00001dqz	Download File View File

CRYSTAL STRUCTURE OF ANTIGEN 85C FROM MYCOBACTERIUM TUBERCULOSIS

Ronning, D.R., Klabunde, T., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 141-146

Released	2000-07-12
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	PROTEIN (ANTIGEN 85-C) (protein)

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1ENY \| pdb_00001eny	Download File View File

CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS

Dessen, A., Quemard, A., Blanchard, J.S., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(1995) Science 267: 1638-1641

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE (protein)
Unique Ligands	NAD

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1ENZ \| pdb_00001enz	Download File View File

CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS

Dessen, A., Quemard, A., Blanchard, J.S., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(1995) Science 267: 1638-1641

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE (protein)
Unique Ligands	NAD

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1EYV \| pdb_00001eyv	Download File View File

THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS

Gopal, B., Haire, L.F., Cox, R.A., Colston, M.J., Major, S., Brannigan, J.A., Smerdon, S.J., Dodson, G.G., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 475-478

Released	2000-05-18
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG (protein)
Unique Ligands	PO4

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1F0N \| pdb_00001f0n	Download File View File

MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B

Anderson, D.H., Harth, G., Horwitz, M.A., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)

(2001) J Mol Biology 307: 671-681

Released	2001-01-24
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ANTIGEN 85B (protein)
Unique Ligands	MES, MPD

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1F0P \| pdb_00001f0p	Download File View File

MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B WITH TREHALOSE

Anderson, D.H., Harth, G., Horwitz, M.A., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)

(2001) J Mol Biology 307: 671-681

Released	2001-01-24
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ANTIGEN 85-B (protein)
Unique Ligands	MES, MPD
Unique branched monosaccharides	GLC

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1F61 \| pdb_00001f61	Download File View File

CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS

Sharma, V., Sharma, S., Hoener zu Bentrup, K.H., McKinney, J.D., Russell, D.G., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 663-668

Released	2000-08-30
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	ISOCITRATE LYASE (protein)
Unique Ligands	MG

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1F8I \| pdb_00001f8i	Download File View File

CRYSTAL STRUCTURE OF ISOCITRATE LYASE:NITROPROPIONATE:GLYOXYLATE COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS

Sharma, V., Sharma, S., Hoener zu Bentrup, K., McKinney, J.D., Russell, D.G., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 663-668

Released	2000-12-30
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	ISOCITRATE LYASE (protein)
Unique Ligands	GLV, MG, SIN

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1F8M \| pdb_00001f8m	Download File View File

CRYSTAL STRUCTURE OF 3-BROMOPYRUVATE MODIFIED ISOCITRATE LYASE (ICL) FROM MYCOBACTERIUM TUBERCULOSIS

Sharma, V., Sharma, S., Hoener zu Bentrup, K., McKinney, J.D., Russell, D.G., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2000) Nat Struct Biol 7: 663-668

Released	2000-12-30
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	ISOCITRATE LYASE (protein)
Unique Ligands	MG, PYR

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1G18 \| pdb_00001g18	Download File View File

RECA-ADP-ALF4 COMPLEX

Datta, S., Prabu, M.M., Vaze, M.B., Ganesh, N., Chandra, N.R., Muniyappa, K., Vijayan, M., TB Structural Genomics Consortium (TBSGC)

(2000) Nucleic Acids Res 28: 4964-4973

Released	2000-12-11
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	RECA PROTEIN (protein)
Unique Ligands	ADP, ALF

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1G19 \| pdb_00001g19	Download File View File

STRUCTURE OF RECA PROTEIN

Datta, S., Prabu, M.M., Vaze, M.B., Ganesh, N., Chandra, N.R., Muniyappa, K., Vijayan, M., TB Structural Genomics Consortium (TBSGC)

(2000) Nucleic Acids Res 28: 4964-4973

Released	2000-12-11
Method	X-RAY DIFFRACTION 3 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	RECA PROTEIN (protein)
Unique Ligands	PO4

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1GR0 \| pdb_00001gr0	Download File View File

myo-inositol 1-phosphate synthase from Mycobacterium tuberculosis in complex with NAD and zinc.

Norman, R.A., Murray-Rust, J., McDonald, N.Q., TB Structural Genomics Consortium (TBSGC)

(2002) Structure 10: 393

Released	2002-03-12
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	INOSITOL-3-PHOSPHATE SYNTHASE (protein)
Unique Ligands	CAC, NAD, ZN

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1HKV \| pdb_00001hkv	Download File View File

mycobacterium diaminopimelate dicarboxylase (lysa)

Gokulan, K., Rupp, B., Pavelka Jr, M.S., Jacobs Jr, W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2003) J Biological Chem 278: 18588

Released	2003-03-20
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	DIAMINOPIMELATE DECARBOXYLASE (protein)
Unique Ligands	LYS, PLP

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1HKW \| pdb_00001hkw	Download File View File

MYCOBACTERIUM DIAMINOPIMELATE DICARBOXYLASE (LysA)

Gokulan, K., Rupp, B., Pavelka Jr, M.S., Jacobs Jr, W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2003) J Biological Chem 278: 18588

Released	2003-03-18
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	DIAMINOPIMELATE DECARBOXYLASE (protein)
Unique Ligands	SO4

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1HTO \| pdb_00001hto	Download File View File

CRYSTALLOGRAPHIC STRUCTURE OF A RELAXED GLUTAMINE SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS

Gill, H.S., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)

(2002) Biochemistry 41: 9863-9872

Released	2002-07-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	GLUTAMINE SYNTHETASE (protein)
Unique Ligands	AMP, CIT, MN

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1HTQ \| pdb_00001htq	Download File View File

Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis

Gill, H.S., Pfluegl, G.M., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)

(2002) Biochemistry 41: 9863-9872

Released	2002-07-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	glutamine synthetase (protein)
Unique Ligands	AMP, CIT, MN

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1HX5 \| pdb_00001hx5	Download File View File

Crystal structure of M. tuberculosis chaperonin-10

Taneja, B., Mande, S.C., TB Structural Genomics Consortium (TBSGC)

(2001) Curr Sci 81: 87-91

Released	2001-08-08
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	10 KDA CHAPERONIN (protein)

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1HZP \| pdb_00001hzp	Download File View File

Crystal Structure of the Myobacterium Tuberculosis Beta-Ketoacyl-Acyl Carrier Protein Synthase III

Scarsdale, J.N., Kazanina, G., He, X., Reynolds, K.A., Wright, H.T., TB Structural Genomics Consortium (TBSGC)

(2001) J Biological Chem 276: 20516-20522

Released	2001-06-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III (protein)
Unique Ligands	DAO, GOL

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1I9G \| pdb_00001i9g	Download File View File

CRYSTAL STRUCTURE OF AN ADOMET DEPENDENT METHYLTRANSFERASE

Gupta, A., Kumar, P.H., Dineshkumar, T.K., Varshney, U., Subramanya, H.S., TB Structural Genomics Consortium (TBSGC)

(2001) J Mol Biology 312: 381-391

Released	2001-09-26
Method	X-RAY DIFFRACTION 1.98 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	HYPOTHETICAL PROTEIN RV2118C (protein)
Unique Ligands	SAM

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1K0R \| pdb_00001k0r	Download File View File

Crystal Structure of Mycobacterium tuberculosis NusA

Gopal, B., Haire, L.F., Gamblin, S.J., Dodson, E.J., Lane, A.N., Papavinasasundaram, K.G., Colston, M.J., Dodson, G., TB Structural Genomics Consortium (TBSGC)

(2001) J Mol Biology 314: 1087-1095

Released	2001-12-21
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	NusA (protein)
Unique Ligands	SO4

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1KP9 \| pdb_00001kp9	Download File View File

Crystal structure of mycolic acid cyclopropane synthase CmaA1, apo-form

Huang, C.-C., Smith, C.V., Jacobs Jr., W.R., Glickman, M.S., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2002) J Biological Chem 277: 11559-11569

Released	2002-01-11
Method	X-RAY DIFFRACTION 2.21 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 1 (protein)
Unique Ligands	ACY

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1KPG \| pdb_00001kpg	Download File View File

Crystal Structure of mycolic acid cyclopropane synthase CmaA1 complexed with SAH and CTAB

Huang, C.-C., Smith, C.V., Jacobs Jr., W.R., Glickman, M.S., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(2002) J Biological Chem 277: 11559-11569

Released	2002-01-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 1 (protein)
Unique Ligands	16A, CO3, SAH

1 to 25 of 369 Structures

Page 1 of 15

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1BVR | pdb_00001bvr

1C3V | pdb_00001c3v

1DQY | pdb_00001dqy

1DQZ | pdb_00001dqz

1ENY | pdb_00001eny

1ENZ | pdb_00001enz

1EYV | pdb_00001eyv

1F0N | pdb_00001f0n

1F0P | pdb_00001f0p

1F61 | pdb_00001f61

1F8I | pdb_00001f8i

1F8M | pdb_00001f8m

1G18 | pdb_00001g18

1G19 | pdb_00001g19

1GR0 | pdb_00001gr0

1HKV | pdb_00001hkv

1HKW | pdb_00001hkw

1HTO | pdb_00001hto

1HTQ | pdb_00001htq

1HX5 | pdb_00001hx5

1HZP | pdb_00001hzp

1I9G | pdb_00001i9g

1K0R | pdb_00001k0r

1KP9 | pdb_00001kp9

1KPG | pdb_00001kpg