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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Timpl, R."

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Search Summary

This query matches 18 Structures.

Refinements

Structure Determination Methodology

experimental (18)

Scientific Name of Source Organism

	Mus musculus (10)
	Homo sapiens (8)

Taxonomy

Eukaryota (18)

Experimental Method

	X-RAY DIFFRACTION (17)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (18)

Refinement Resolution (Å)

	1.5 - 2.0 (2)
	2.0 - 2.5 (10)
	2.5 - 3.0 (3)
	3.0 - 3.5 (2)

Release Date

	1995 - 1999 (9)
	2000 - 2004 (8)
	2005 - 2009 (1)

Enzyme Classification Name

Transferases (1)

Symmetry Type

	Asymmetric (14)
	Cyclic (4)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (9)
	Small proteins (6)
	All beta proteins (4)
	All alpha proteins (3)
	Artifacts (1)

AllSelected

1 to 18 of 18 Structures

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1BMO \| pdb_00001bmo	Download File View File

BM-40, FS/EC DOMAIN PAIR

Hohenester, E., Maurer, P., Timpl, R.

(1997) EMBO J 16: 3778-3786

Released	1997-10-15
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Homo sapiens
Macromolecule	BM-40 (protein)
Unique Ligands	CA
Unique branched monosaccharides	NAG

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1BNL \| pdb_00001bnl	Download File View File

ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN

Ding, Y.-H., Javaherian, K., Lo, K.-M., Chopra, R., Boehm, T., Lanciotti, J., Harris, B.A., Li, Y., Shapiro, R., Hohenester, E., Timpl, R., Folkman, J., Wiley, D.C.

(1998) Proc Natl Acad Sci U S A 95: 10443-10448

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	COLLAGEN XVIII (protein)
Unique Ligands	ZN

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1BY2 \| pdb_00001by2	Download File View File

STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN

Hohenester, E., Sasaki, T., Timpl, R.

(1999) Nat Struct Biol 6: 228-232

Released	1999-05-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	MAC-2 BINDING PROTEIN (protein)
Unique Ligands	NAG

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1DY0 \| pdb_00001dy0	Download File View File

Murine endostatin, crystal form II

Hohenester, E., Sasaki, T., Timpl, R.

(2000) J Mol Biology 297: 1

Released	2000-04-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mus musculus
Macromolecule	COLLAGEN ALPHA1(XVIII) CHAIN (protein)
Unique Ligands	ZN

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1DY1 \| pdb_00001dy1	Download File View File

Murine endostatin, crystal form III

Hohenester, E., Sasaki, T., Timpl, R.

(2000) J Mol Biology 297: 1

Released	2001-01-21
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mus musculus
Macromolecule	COLLAGEN ALPHA1(XVIII) CHAIN (protein)
Unique Ligands	ZN

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1DY2 \| pdb_00001dy2	Download File View File

Murine collagen alpha1(XV), endostatin domain

Tisi, D., Hohenester, E., Sasaki, T., Timpl, R.

(2000) J Mol Biology 301: 1179

Released	2001-01-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mus musculus
Macromolecule	COLLAGEN ALPHA1(XV) CHAIN (protein)
Unique Ligands	SO4

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1GL4 \| pdb_00001gl4	Download File View File

Nidogen-1 G2/Perlecan IG3 Complex

Kvansakul, M., Hopf, M., Ries, A., Timpl, R., Hohenester, E.

(2001) EMBO J 20: 5342

Released	2001-11-28
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mus musculus
Macromolecule	BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN (protein) NIDOGEN-1 (protein)
Unique Ligands	EPE, ZN

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1H30 \| pdb_00001h30	Download File View File

C-terminal LG domain pair of human Gas6

Sasaki, T., Knyazev, P.G., Cheburkin, Y., Gohring, W., Tisi, D., Ullrich, A., Timpl, R., Hohenester, E.

(2002) J Biological Chem 277: 44164

Released	2003-01-30
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	GROWTH-ARREST-SPECIFIC PROTEIN (protein)
Unique Ligands	CA, SO4

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1H4U \| pdb_00001h4u	Download File View File

Domain G2 of mouse nidogen-1

Hopf, M., Gohring, W., Ries, A., Timpl, R., Hohenester, E.

(2001) Nat Struct Biol 8: 634

Released	2001-06-28
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mus musculus
Macromolecule	NIDOGEN-1 (protein)

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1KLO \| pdb_00001klo	Download File View File

CRYSTAL STRUCTURE OF THREE CONSECUTIVE LAMININ-TYPE EPIDERMAL GROWTH FACTOR-LIKE (LE) MODULES OF LAMININ GAMMA1 CHAIN HARBORING THE NIDOGEN BINDING SITE

Stetefeld, J., Mayer, U., Timpl, R., Huber, R.

(1996) J Mol Biology 257: 644-657

Released	1997-08-20
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mus musculus
Macromolecule	LAMININ (protein)

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1KOE \| pdb_00001koe	Download File View File

ENDOSTATIN

Hohenester, E., Sasaki, T., Olsen, B.R., Timpl, R.

(1998) EMBO J 17: 1656-1664

Released	1999-02-16
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Mus musculus
Macromolecule	ENDOSTATIN (protein)

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1LI1 \| pdb_00001li1	Download File View File

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

Than, M.E., Henrich, S., Huber, R., Ries, A., Mann, K., Kuhn, K., Timpl, R., Bourenkov, G.P., Bartunik, H.D., Bode, W.

(2002) Proc Natl Acad Sci U S A 99: 6607-6612

Released	2002-05-22
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Collagen alpha 1(IV) (protein) Collagen alpha 2(IV) (protein)
Unique Ligands	ACT

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1NUB \| pdb_00001nub	Download File View File

HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR

Hohenester, E., Sasaki, T., Timpl, R.

(1998) EMBO J 17: 1625-1634

Released	1998-12-30
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	BASEMENT MEMBRANE PROTEIN BM-40 (protein)
Unique Ligands	CA
Unique branched monosaccharides	NAG

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1OKQ \| pdb_00001okq	Download File View File

LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT

Wizemann, H., Garbe, J.H.O., Friedrich, M.V.K., Timpl, R., Sasaki, T., Hohenester, E.

(2003) J Mol Biology 332: 635

Released	2003-09-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mus musculus
Macromolecule	LAMININ ALPHA 2 CHAIN (protein)
Unique Ligands	CA

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1QU0 \| pdb_00001qu0	Download File View File

CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN

Hohenester, E., Tisi, D., Talts, J.F., Timpl, R.

(1999) Mol Cell 4: 783-792

Released	1999-12-03
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Mus musculus
Macromolecule	LAMININ ALPHA2 CHAIN (protein)
Unique Ligands	CA, SO4

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1SRA \| pdb_00001sra	Download File View File

STRUCTURE OF A NOVEL EXTRACELLULAR CA2+-BINDING MODULE IN BM-40(SLASH)SPARC(SLASH)OSTEONECTIN

Hohenester, E., Maurer, P., Hohenadl, C., Timpl, R., Jansonius, J.N., Engel, J.

(1996) Nat Struct Biol 3: 67-73

Released	1996-03-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	SPARC (protein)
Unique Ligands	CA

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1TLE \| pdb_00001tle	Download File View File

LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES

Baumgartner, R., Czisch, M., Mayer, U., Schl, E.P., Huber, R., Timpl, R., Holak, T.A.

(1996) J Mol Biology 257: 658-668

Released	1997-02-12
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	LAMININ (protein)

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2C5D \| pdb_00002c5d	Download File View File

Structure of a minimal Gas6-Axl complex

Sasaki, T., Knyazev, P.G., Clout, N.J., Cheburkin, Y., Goehring, W., Ullrich, A., Timpl, R., Hohenester, E.

(2006) EMBO J 25: 80

Released	2005-12-19
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Homo sapiens
Macromolecule	GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR (protein) TYROSINE-PROTEIN KINASE RECEPTOR UFO (protein)
Unique Ligands	CA, NI, SO4
Unique branched monosaccharides	NAG

1 to 18 of 18 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1BMO | pdb_00001bmo

BM-40, FS/EC DOMAIN PAIR

1BNL | pdb_00001bnl

ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN

1BY2 | pdb_00001by2

STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN

1DY0 | pdb_00001dy0

Murine endostatin, crystal form II

1DY1 | pdb_00001dy1

Murine endostatin, crystal form III

1DY2 | pdb_00001dy2

Murine collagen alpha1(XV), endostatin domain

1GL4 | pdb_00001gl4

Nidogen-1 G2/Perlecan IG3 Complex

1H30 | pdb_00001h30

C-terminal LG domain pair of human Gas6

1H4U | pdb_00001h4u

Domain G2 of mouse nidogen-1

1KLO | pdb_00001klo

CRYSTAL STRUCTURE OF THREE CONSECUTIVE LAMININ-TYPE EPIDERMAL GROWTH FACTOR-LIKE (LE) MODULES OF LAMININ GAMMA1 CHAIN HARBORING THE NIDOGEN BINDING SITE

1KOE | pdb_00001koe

ENDOSTATIN

1LI1 | pdb_00001li1

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

1NUB | pdb_00001nub

HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR

1OKQ | pdb_00001okq

LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT

1QU0 | pdb_00001qu0

CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN

1SRA | pdb_00001sra

STRUCTURE OF A NOVEL EXTRACELLULAR CA2+-BINDING MODULE IN BM-40(SLASH)SPARC(SLASH)OSTEONECTIN

1TLE | pdb_00001tle

LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES

2C5D | pdb_00002c5d

Structure of a minimal Gas6-Axl complex

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1BMO | pdb_00001bmo

1BNL | pdb_00001bnl

1BY2 | pdb_00001by2

1DY0 | pdb_00001dy0

1DY1 | pdb_00001dy1

1DY2 | pdb_00001dy2

1GL4 | pdb_00001gl4

1H30 | pdb_00001h30

1H4U | pdb_00001h4u

1KLO | pdb_00001klo

1KOE | pdb_00001koe

1LI1 | pdb_00001li1

1NUB | pdb_00001nub

1OKQ | pdb_00001okq

1QU0 | pdb_00001qu0

1SRA | pdb_00001sra

1TLE | pdb_00001tle

2C5D | pdb_00002c5d