RCSB PDB: Search

8C84	Download File View File

Crystal structure of MADS-box/MEF2D N-terminal domain complex

Chinellato, M., Carli, A., Perin, S., Mazzoccato, Y., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-01-31
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	MEF2D protein (protein) DNA (5'-D(PAPAPCPTPAPTPTPTPAPTPAPAPGPA)-3') (nucleic acid) DNA (5'-D(PTPCPTPTPAPTPAPAPAPTPAPGPTPT)-3') (nucleic acid)

Explore in 3D

8PDE	Download File View File

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC4 deacetylase binding motif

Chinellato, M., Carli, A., Perin, S., Mazzocato, Y., Biondi, B., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	HDAC4 (histone deacetylase 4) binding motif peptide:GSGEVKMKLQEFVLNKK (protein) MEF2D protein (protein) DNA (5'-D(PAPAPCPTPAPTPTPTPAPTPAPAPGPA)-3') (nucleic acid) DNA (5'-D(PTPCPTPTPAPTPAPAPAPTPAPGPTPT)-3') (nucleic acid)

Explore in 3D

8Q9N	Download File View File

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V.

Chinellato, M., Carli, A., Perin, S., Mazzocato, Y., Biondi, B., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-06-26
Method	X-RAY DIFFRACTION 1.51 Å
Organisms	Homo sapiens
Macromolecule	MEF2D protein (protein) myocyte enhancer-binding factor 2-interacting transcriptional repressor (MITR or HDAC9) L151V mutant peptide: GLU-VAL-LYS-GLN-LYS-LEU-GLN-GLU-PHE-VAL-LEU-SER-LYS (protein) DNA MADS box (nucleic acid)
Unique Ligands	DMS

Explore in 3D

8Q9P	Download File View File

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC5 deacetylase binding motif

Chinellato, M., Carli, A., Perin, S., Mazzocato, Y., Biondi, B., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	HDAC5 (histone deacetylase 5) binding motif peptide: TRP-GLY-SER-GLY-GLU-VAL-LYS-LEU-ARG-LEU-GLN-GLU-PHE-LEU-LEU-SER-LYS-SER (protein) MEF2D protein (protein) MADS box dsDNA fw: AACTATTTATAAGA (nucleic acid) MADS box dsNA rev:TCTTATAAATAGTT (nucleic acid)

Explore in 3D

8Q9Q	Download File View File

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC7 deacetylase binding motif

Chinellato, M., Carli, A., Perin, S., Mazzocato, Y., Biondi, B., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	DNA molecule Homo sapiens
Macromolecule	HDAC7 (histone deacetylase 7) binding motif peptide: GLY-VAL-VAL-LYS-GLN-LYS-LEU-ALA-GLU-VAL-ILE-LEU-LYS-LYS-GLN (protein) MEF2D protein (protein) MADS box dsDNA: AACTATTTATAAGA (nucleic acid) MADS box dsDNA: TCTTATAAATAGTT (nucleic acid)

Explore in 3D

8Q9R	Download File View File

Crystal structure of MADS-box/MEF2D N-terminal domain bound to dsDNA and HDAC9 deacetylase binding motif

Chinellato, M., Carli, A., Perin, S., Mazzoccato, Y., Di Giorgio, E., Brancolini, C., Angelini, A., Cendron, L.

(2024) J Mol Biology 436: 168541-168541

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	DNA molecule Homo sapiens
Macromolecule	Histone deacetylase 9 (HDAC9) binding motif peptide: EVKQKLQEFLLSKS (protein) MEF2D protein (protein) MADS box dsDNA: AACTATTTATAAGA (nucleic acid) MADS box dsDNA: TCTTATAAATAGT (nucleic acid)

Explore in 3D

9EX8	Download File View File

Free form of a mutant of SARS-CoV-2 main protease Mpro.

Battistutta, R., Fornasier, E., Giachin, G.

(2024) Commun Biol 7: 1435-1435

Released	2025-02-12
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	Non-structural protein 7 (protein)

Explore in 3D

9EXU	Download File View File

Complex of a mutant of the SARS-CoV-2 main protease Mpro with the nsp4/5 substrate peptide (cocrystallization).

Battistutta, R., Fornasier, E., Giachin, G.

(2024) Commun Biol 7: 1435-1435

Released	2025-02-12
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	Non-structural protein 7 (protein) THR-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-ARG-LYS (protein)

Explore in 3D

9EYA	Download File View File

Complex of a mutant of the SARS-CoV-2 main protease Mpro with the nsp4/5 substrate peptide (soaking).

Battistutta, R., Fornasier, E., Giachin, G.

(2024) Commun Biol 7: 1435-1435

Released	2025-02-12
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	Non-structural protein 7 (protein) THR-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-ARG-LYS (protein)

Explore in 3D

9EZ4	Download File View File

Complex of a mutant of the SARS-CoV-2 main protease Mpro with the nsp5/6 substrate peptide.

Battistutta, R., Fornasier, E., Giachin, G.

(2024) Commun Biol 7: 1435-1435

Released	2025-02-12
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	GLY-VAL-THR-PHE-GLN-SER-ALA-VAL (protein) Non-structural protein 7 (protein) Replicase polyprotein 1a (protein)
Unique Ligands	EDO, GLN, PEG

Explore in 3D

9EZ6	Download File View File

Complex of a mutant of the SARS-CoV-2 main protease Mpro with the nsp14/15 substrate peptide.

Battistutta, R., Fornasier, E., Giachin, G.

(2024) Commun Biol 7: 1435-1435

Released	2025-02-12
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	Replicase polyprotein 1a (protein) THR-PHE-THR-ARG-LEU-GLN-SER-LEU-GLU-ASN (protein)
Unique Ligands	DMS, EDO, GLN, NA, PEG

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type