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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Cuello, L.G."

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Search Summary

This query matches 31 Structures.

Refinements

Structure Determination Methodology

experimental (31)

Scientific Name of Source Organism

	Mus musculus (20)
	Streptomyces lividans (20)
	Dickeya chrysanthemi (3)
	Gloeobacter violaceus (3)
	Lama glama (2)
	Streptomyces coelicolor A3(2) (2)
	synthetic construct (2)
	Streptomyces (1)

Taxonomy

	Bacteria (29)
	Eukaryota (22)
	other sequences (2)

Experimental Method

	X-RAY DIFFRACTION (26)
	SOLUTION NMR (5)

Polymer Entity Type

Protein (31)

Refinement Resolution (Å)

	2.0 - 2.5 (8)
	2.5 - 3.0 (5)
	3.0 - 3.5 (11)
	3.5 - 4.0 (2)

Release Date

	2000 - 2004 (3)
	2005 - 2009 (3)
	2010 - 2014 (12)
	2015 - 2019 (12)
	2020 - 2024 (1)

Membrane Protein Annotation

	PDBTM (29)
	MemProtMD (27)
	mpstruc (19)
	OPM (15)

Symmetry Type

	Cyclic (23)
	Asymmetric (14)

SCOP Classification

	All beta proteins (14)
	Membrane and cell surface proteins and peptides (15)
	Artifacts (14)

AllSelected

1 to 25 of 31 Structures

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1F6G \| pdb_00001f6g	Download File View File

POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD

Cortes, D.M., Perozo, E.

(2001) J Gen Physiol 117: 165-180

Released	2001-02-21
Method	SOLUTION NMR
Organisms	Streptomyces lividans
Macromolecule	VOLTAGE-GATED POTASSIUM CHANNEL (protein)

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1JQ1 \| pdb_00001jq1	Download File View File

POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL

Liu, Y.-S., Sompornpisut, P., Perozo, E.

(2001) Nat Struct Biol 8: 883-887

Released	2001-10-03
Method	SOLUTION NMR
Organisms	Streptomyces lividans
Macromolecule	VOLTAGE-GATED POTASSIUM CHANNEL (protein)

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1JQ2 \| pdb_00001jq2	Download File View File

POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL

Liu, Y.-S., Sompornpisut, P., Perozo, E.

(2001) Nat Struct Biol 8: 883-887

Released	2001-10-03
Method	SOLUTION NMR
Organisms	Streptomyces lividans
Macromolecule	VOLTAGE-GATED POTASSIUM CHANNEL (protein)

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1ZWI \| pdb_00001zwi	Download File View File

Structure of mutant KcsA potassium channel

Cordero-Morales, J.F., Cuello, L.G., Zhao, Y., Jogini, V., Cortes, D.M., Roux, B., Perozo, E.

(2006) Nat Struct Mol Biol 13: 311-318

Released	2006-03-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) monoclonal antibody light chain (protein) monoclonal antibody, heavy chain (protein)
Unique Ligands	DGA, F09, K

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2ATK \| pdb_00002atk	Download File View File

Structure of a mutant KcsA K+ channel

Cordero-Morales, J.F., Cuello, L.G., Zhao, Y., Jogini, V., Chakrapani, S., Roux, B., Perozo, E.

(2006) Nat Struct Mol Biol 13: 311-318

Released	2006-03-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	ANTIBODY FAB FRAGMENT HEAVY CHAIN (protein) ANTIBODY FAB FRAGMENT LIGHT CHAIN (protein) Voltage-gated potassium channel (protein)
Unique Ligands	F09, K

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2KIR \| pdb_00002kir	Download File View File

Solution structure of a designer toxin, mokatoxin-1

Biancalana, M., Koide, A., Takacs, Z., Goldstein, S., Koide, S.

(2009) Proc Natl Acad Sci U S A 106: 22211-22216

Released	2009-12-29
Method	SOLUTION NMR
Organisms	synthetic construct
Macromolecule	Designer toxin (protein)

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2N6B \| pdb_00002n6b	Download File View File

NMR structure of the de-novo toxin Hui1

Mendelman, N., Zhao, R., Goldstein, S.A.N., Chill, J.H.

(2015) Proc Natl Acad Sci U S A 112: E7013-E7021

Released	2015-12-16
Method	SOLUTION NMR
Organisms	synthetic construct
Macromolecule	Hui1 (protein)

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3F5W \| pdb_00003f5w	Download File View File

KcsA Potassium channel in the open-inactivated state with 32 A opening at T112

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Antibody heavy chain (protein) Antibody light chain (protein) Voltage-gated potassium channel (protein)
Unique Ligands	K

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3F7V \| pdb_00003f7v	Download File View File

KcsA Potassium channel in the open-inactivated state with 23 A opening at T112

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody fab fragment Heavy chain (protein) antibody fab fragment light chain (protein)
Unique Ligands	K

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3F7Y \| pdb_00003f7y	Download File View File

KcsA Potassium channel in the partially open state with 17 A opening at T112

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody fab fragment heavy chain (protein) antibody fab fragment light chain (protein)
Unique Ligands	K

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3FB5 \| pdb_00003fb5	Download File View File

KcsA potassium channel in the partially open state with 14.5 A opening at T112

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody Fab fragment heavy chain (protein) antibody Fab fragment light chain (protein)
Unique Ligands	K

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3FB6 \| pdb_00003fb6	Download File View File

KcsA Potassium channel in the partially open state with 16 A opening at T112

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 3 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody fab fragment heavy chain (protein) antibody fab fragment light chain (protein)
Unique Ligands	K

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3FB7 \| pdb_00003fb7	Download File View File

Open KcsA potassium channel in the presence of Rb+ ion

Cuello, L.G., Jogini, V., Cortes, D.M., Pan, A.C., Gagnon, D.H., Cordero-Morales, J.F., Chakrapani, S., Roux, B., Perozo, E.

To be published

Released	2010-07-14
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody fab fragment heavy chain (protein) antibody fab fragment light chain (protein)
Unique Ligands	RB

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3FB8 \| pdb_00003fb8	Download File View File

KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Voltage-gated potassium channel (protein) antibody fab fragment heavy chain (protein) antibody fab fragment light chain (protein)
Unique Ligands	RB

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3HPL \| pdb_00003hpl	Download File View File

KcsA E71H-F103A mutant in the closed state

Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E.

(2010) Nature 466: 272-275

Released	2010-06-23
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Antibody Fab heavy chain (protein) Antibody fab light chain (protein) Voltage-gated potassium channel (protein)
Unique Ligands	K

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3PJS \| pdb_00003pjs	Download File View File

Mechanism of Activation Gating in the Full-Length KcsA K+ Channel

Uysal, S., Cuello, L.G., Kossiakoff, A., Perozo, E.

(2011) Proc Natl Acad Sci U S A 108: 11896-11899

Released	2011-07-06
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	FAB heavy chain (protein) FAB light chain (protein) Voltage-gated potassium channel (protein)

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4LMJ \| pdb_00004lmj	Download File View File

GLIC Liganded-closed-channel Conformation, Mutant T25'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.44 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	CL, LMT, NA

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4LMK \| pdb_00004lmk	Download File View File

GLIC Liganded-closed-channel Conformation, Mutant Y27'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.22 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	CL, LMT, NA

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4LML \| pdb_00004lml	Download File View File

GLIC double mutant I9'A T25'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)

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5VK6 \| pdb_00005vk6	Download File View File

Open conformation of KcsA non-inactivating E71A mutant

Cuello, L.G., Perozo, E.

(2017) Elife 6:

Released	2017-12-06
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Antibody Heavy Chain (protein) Antibody Light Chain (protein) pH-gated potassium channel KcsA (protein)
Unique Ligands	1EM, F09, K

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5VKE \| pdb_00005vke	Download File View File

Open conformation of KcsA deep-inactivated

Cuello, L.G., Perozo, E., Cortes, D.M.

(2017) Elife 6:

Released	2017-12-06
Method	X-RAY DIFFRACTION 2.37 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Antibody Heavy Chain (protein) Antibody Light Chain (protein) pH-gated potassium channel KcsA (protein)
Unique Ligands	1EM, F09, K

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5VKH \| pdb_00005vkh	Download File View File

Closed conformation of KcsA Y82A-F103A mutant

Cuello, L.G., Perozo, E., Cortes, D.M.

(2017) Elife 6:

Released	2017-12-06
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Mus musculus Streptomyces lividans
Macromolecule	Antibody Heavy Chain (protein) Antibody Light Chain (protein) pH-gated potassium channel KcsA (protein)
Unique Ligands	1EM, F09, K

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6BY2 \| pdb_00006by2	Download File View File

Closed and deep-inactivated conformation of KcsA-T75A mutant

Labro, A.J., Cortes, D.M., Tilegenova, C., Cuello, L.G.

(2018) Proc Natl Acad Sci U S A 115: 5426-5431

Released	2018-05-09
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Mus musculus Streptomyces coelicolor A3(2)
Macromolecule	Antibody Heavy Chain (protein) Antibody Light Chain (protein) pH-gated potassium channel KcsA (protein)
Unique Ligands	DGA, F09, K

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6BY3 \| pdb_00006by3	Download File View File

Open and conductive conformation of KcsA-T75A mutant

Labro, A.J., Cortes, D.M., Tilegenova, C., Cuello, L.G.

(2018) Proc Natl Acad Sci U S A 115: 5426-5431

Released	2018-05-09
Method	X-RAY DIFFRACTION 2.37 Å
Organisms	Mus musculus Streptomyces coelicolor A3(2)
Macromolecule	Antibody Heavy Chain (protein) Antibody Light Chain (protein) pH-gated potassium channel KcsA (protein)
Unique Ligands	DGA, F09, K

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6HJX \| pdb_00006hjx	Download File View File

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72

Spurny, R., Govaerts, C., Evans, G.L., Pardon, E., Steyaert, J., Ulens, C.

(2019) Nat Chem Biol 15: 1156-1164

Released	2019-10-09
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Dickeya chrysanthemi Lama glama
Macromolecule	Unique protein chains: 6
Unique Ligands	LMT, MES, NA, P6G, PTY

1 to 25 of 31 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1F6G | pdb_00001f6g

1JQ1 | pdb_00001jq1

1JQ2 | pdb_00001jq2

1ZWI | pdb_00001zwi

2ATK | pdb_00002atk

2KIR | pdb_00002kir

2N6B | pdb_00002n6b

3F5W | pdb_00003f5w

3F7V | pdb_00003f7v

3F7Y | pdb_00003f7y

3FB5 | pdb_00003fb5

3FB6 | pdb_00003fb6

3FB7 | pdb_00003fb7

3FB8 | pdb_00003fb8

3HPL | pdb_00003hpl

3PJS | pdb_00003pjs

4LMJ | pdb_00004lmj

4LMK | pdb_00004lmk

4LML | pdb_00004lml

5VK6 | pdb_00005vk6

5VKE | pdb_00005vke

5VKH | pdb_00005vkh

6BY2 | pdb_00006by2

6BY3 | pdb_00006by3

6HJX | pdb_00006hjx