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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Hakoshima, T."

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Search Summary

This query matches 103 Structures.

Refinements

Structure Determination Methodology

experimental (103)

Scientific Name of Source Organism

	Mus musculus (32)
	Homo sapiens (27)
	Arabidopsis thaliana (10)
	Rattus norvegicus (6)
	Escherichia coli (5)
	Weissella cibaria (5)
	Bos taurus (4)
	Saccharomyces cerevisiae (3)
	Chromobacterium sp. USM2 (2)
	Oryza sativa Japonica Group (2)

More...

Taxonomy

	Eukaryota (81)
	Bacteria (18)
	Eukaryota (eukaryotes) (6)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (101)
	SOLUTION NMR (2)

Polymer Entity Type

	Protein (98)
	DNA (10)

Refinement Resolution (Å)

	1.0 - 1.5 (11)
	1.5 - 2.0 (22)
	2.0 - 2.5 (29)
	2.5 - 3.0 (30)
	3.0 - 3.5 (6)
	3.5 - 4.0 (1)
	> 4.5 (2)

Release Date

	1990 - 1994 (1)
	1995 - 1999 (13)
	2000 - 2004 (11)
	2005 - 2009 (25)
	2010 - 2014 (22)
	2015 - 2019 (14)
	2020 - 2024 (17)

Enzyme Classification Name

	Hydrolases (31)
	Transferases (15)
	Oxidoreductases (5)
	Isomerases (6)
	Ligases (1)
	Lyases (1)

Membrane Protein Annotation

	OPM (3)
	MemProtMD (2)
	PDBTM (2)
	mpstruc (2)

Symmetry Type

	Asymmetric (68)
	Cyclic (27)
	Dihedral (7)

SCOP Classification

	Alpha and beta proteins (a+b) (17)
	All alpha proteins (25)
	All beta proteins (18)
	Alpha and beta proteins (a/b) (11)
	Coiled coil proteins (2)
	Artifacts (5)

AllSelected

1 to 25 of 103 Structures

Page 1 of 5

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1A0A \| pdb_00001a0a	Download File View File

PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX

Shimizu, T., Toumoto, A., Ihara, K., Shimizu, M., Kyogoku, Y., Ogawa, N., Oshima, Y., Hakoshima, T.

(1997) EMBO J 16: 4689-4697

Released	1998-03-18
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4) (protein) DNA (5'-D(CPTPAPGPTPCPCPCPAPCPGPTPGPTPGPAPG )-3') (nucleic acid) DNA (5'-D(CPTPCPAPCPAPCPGPTPGPGPGPAPCPTPAPG )-3') (nucleic acid)

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1A0B \| pdb_00001a0b	Download File View File

HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI

Kato, M., Mizuno, T., Shimizu, T., Hakoshima, T.

(1997) Cell 88: 717-723

Released	1998-03-18
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Escherichia coli
Macromolecule	AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB (protein)
Unique Ligands	ZN

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1A2B \| pdb_00001a2b	Download File View File

HUMAN RHOA COMPLEXED WITH GTP ANALOGUE

Ihara, K., Muraguchi, S., Kato, M., Shimizu, T., Shirakawa, M., Kuroda, S., Kaibuchi, K., Hakoshima, T.

(1998) J Biological Chem 273: 9656-9666

Released	1998-06-17
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	TRANSFORMING PROTEIN RHOA (protein)
Unique Ligands	GSP, MG

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1BDJ \| pdb_00001bdj	Download File View File

COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY

Kato, M., Mizuno, T., Shimizu, T., Hakoshima, T.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1257-1263

Released	1999-05-11
Method	X-RAY DIFFRACTION 2.68 Å
Organisms	Escherichia coli
Macromolecule	AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB (protein) CHEY (protein)
Unique Ligands	SO4

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1CC0 \| pdb_00001cc0	Download File View File

CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX

Longenecker, K.L., Read, P., Derewenda, U., Dauter, Z., Garrard, S., Walker, L., Somlyo, A.V., Somlyo, A.P., Nakamoto, R.K., Derewenda, Z.S.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1503-1515

Released	2000-01-07
Method	X-RAY DIFFRACTION 5 Å
Organisms	Homo sapiens
Macromolecule	rho GDP dissociation inhibitor alpha (protein) transforming protein rhoA (protein)
Unique Ligands	GDP, MG

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1CXZ \| pdb_00001cxz	Download File View File

CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1

Maesaki, R., Ihara, K., Shimizu, T., Kuroda, S., Kaibuchi, K., Hakoshima, T.

(1999) Mol Cell 4: 793-803

Released	1999-10-08
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)) (protein) PROTEIN (PKN) (protein)
Unique Ligands	GSP, MG

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1DJ6 \| pdb_00001dj6	Download File View File

COMPLEX OF A Z-DNA HEXAMER, D(CG)3, WITH SYNTHETIC POLYAMINE AT ROOM TEMPERATURE

Ohishi, H., Tomita, K.-i., Nakanishi, I., Ohtsuchi, M., Hakoshima, T., Rich, A.

(2002) FEBS Lett 523: 29-34

Released	1999-12-18
Method	X-RAY DIFFRACTION 1 Å
Macromolecule	5'-D(CPGPCPGPCPG)-3' (nucleic acid)
Unique Ligands	104, MG

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1DPF \| pdb_00001dpf	Download File View File

CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP

Shimizu, T., Ihara, K., Maesaki, R., Kuroda, S., Kaibuchi, K., Hakoshima, T.

(2000) J Biological Chem 275: 18311-18317

Released	2000-06-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	RHOA (protein)
Unique Ligands	GDP

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1GC6 \| pdb_00001gc6	Download File View File

CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE

Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.

(2000) EMBO J 19: 4449-4462

Released	2000-09-20
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Mus musculus
Macromolecule	RADIXIN (protein)
Unique Ligands	I3P

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1GC7 \| pdb_00001gc7	Download File View File

CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN

Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.

(2000) EMBO J 19: 4449-4462

Released	2000-09-20
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mus musculus
Macromolecule	RADIXIN (protein)

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1GD2 \| pdb_00001gd2	Download File View File

CRYSTAL STRUCTURE OF BZIP TRANSCRIPTION FACTOR PAP1 BOUND TO DNA

Fujii, Y., Shimizu, T., Toda, T., Yanagida, M., Hakoshima, T.

(2000) Nat Struct Biol 7: 889-893

Released	2000-10-02
Method	X-RAY DIFFRACTION 2 Å
Organisms	Schizosaccharomyces pombe
Macromolecule	TRANSCRIPTION FACTOR PAP1 (protein) DNA (5'-D(APGPGPTPTPAPCPGPTPAPAPCP*C)-3') (nucleic acid)

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1IS7 \| pdb_00001is7	Download File View File

Crystal structure of rat GTPCHI/GFRP stimulatory complex

Maita, N., Okada, K., Hatakeyama, K., Hakoshima, T.

(2002) Proc Natl Acad Sci U S A 99: 1212-1217

Released	2002-02-20
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Rattus norvegicus
Macromolecule	GTP Cyclohydrolase I (protein) GTP Cyclohydrolase I Feedback Regulatory Protein (protein)
Unique Ligands	K, PHE

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1IS8 \| pdb_00001is8	Download File View File

Crystal structure of rat GTPCHI/GFRP stimulatory complex plus Zn

Maita, N., Okada, K., Hatakeyama, K., Hakoshima, T.

(2002) Proc Natl Acad Sci U S A 99: 1212-1217

Released	2002-02-20
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Rattus norvegicus
Macromolecule	GTP Cyclohydrolase I (protein) GTP Cyclohydrolase I Feedback Regulatory Protein (protein)
Unique Ligands	K, PHE, ZN

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1ISN \| pdb_00001isn	Download File View File

Crystal structure of merlin FERM domain

Shimizu, T., Seto, A., Maita, N., Hamada, K., Tsukita, S., Tsukita, S., Hakoshima, T.

(2002) J Biological Chem 277: 10332-10336

Released	2002-04-03
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Mus musculus
Macromolecule	merlin (protein)

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1J19 \| pdb_00001j19	Download File View File

Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide

Hamada, K., Shimizu, T., Yonemura, S., Tsukita, S., Tsukita, S., Hakoshima, T.

(2003) EMBO J 22: 502-514

Released	2003-03-11
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	16-mer peptide from Intercellular adhesion molecule-2 (protein) radixin (protein)

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1NPM \| pdb_00001npm	Download File View File

NEUROPSIN, A SERINE PROTEASE EXPRESSED IN THE LIMBIC SYSTEM OF MOUSE BRAIN

Kishi, T., Kato, M., Shimizu, T., Kato, K., Matsumoto, K., Yoshida, S., Shiosaka, S., Hakoshima, T.

(1999) J Biological Chem 274: 4220-4224

Released	1999-03-23
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mus musculus
Macromolecule	NEUROPSIN (protein)
Unique Ligands	NAG

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1QQ2 \| pdb_00001qq2	Download File View File

CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.

Hirotsu, S., Abe, Y., Okada, K., Nagahara, N., Hori, H., Nishino, T., Hakoshima, T.

(1999) Proc Natl Acad Sci U S A 96: 12333-12338

Released	1999-10-29
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Rattus norvegicus
Macromolecule	THIOREDOXIN PEROXIDASE 2 (protein)
Unique Ligands	CL

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1RLS \| pdb_00001rls	Download File View File

CRYSTAL STRUCTURE OF RNASE T1 COMPLEXED WITH THE PRODUCT NUCLEOTIDE 3'-GMP. STRUCTURAL EVIDENCE FOR DIRECT INTERACTION OF HISTIDINE 40 AND GLUTAMIC ACID 58 WITH THE 2'-HYDROXYL GROUP OF RIBOSE

Gohda, K., Oka, K.-I., Tomita, K.-I., Hakoshima, T.

(1994) J Biological Chem 269: 17531-17536

Released	1994-12-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Aspergillus oryzae
Macromolecule	RIBONUCLEASE T1 (protein)
Unique Ligands	3GP, CA

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1UIX \| pdb_00001uix	Download File View File

Coiled-coil structure of the RhoA-binding domain in Rho-kinase

Shimizu, T., Ihara, K., Maesaki, R., Amano, M., Kaibuchi, K., Hakoshima, T.

(2003) J Biological Chem 278: 46046-46051

Released	2003-10-21
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus
Macromolecule	Rho-associated kinase (protein)

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1UJB \| pdb_00001ujb	Download File View File

Structure of the protein histidine phosphatase SixA

Hamada, K., Kato, M., Shimizu, T., Ihara, K., Mizuno, T., Hakoshima, T.

(2005) Genes Cells 10: 1-11

Released	2005-01-25
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Escherichia coli
Macromolecule	Phosphohistidine phosphatase sixA (protein)
Unique Ligands	CA

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1UJC \| pdb_00001ujc	Download File View File

Structure of the protein histidine phosphatase SixA complexed with tungstate

Hamada, K., Kato, M., Shimizu, T., Ihara, K., Mizuno, T., Hakoshima, T.

(2005) Genes Cells 10: 1-11

Released	2005-01-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli
Macromolecule	Phosphohistidine phosphatase sixA (protein)
Unique Ligands	CA, WO4

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1UL1 \| pdb_00001ul1	Download File View File

Crystal structure of the human FEN1-PCNA complex

Sakurai, S., Kitano, K., Yamaguchi, H., Hamada, K., Okada, K., Fukuda, K., Uchida, M., Ohtsuka, E., Morioka, H., Hakoshima, T.

(2005) EMBO J 24: 683-693

Released	2005-03-01
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Flap endonuclease-1 (protein) Proliferating cell nuclear antigen (protein)
Unique Ligands	MG

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1VTG \| pdb_00001vtg	Download File View File

THE MOLECULAR STRUCTURE OF A DNA-TRIOSTIN A COMPLEX

Wang, A.H.-J., Ughetto, G., Quigley, G.J., Hakoshima, T., Van Der Marel, G.A., Van Boom, J.H., Rich, A.

(1984) Science 225: 1115-1121

Released	2011-07-13
Method	X-RAY DIFFRACTION 1.67 Å
Organisms	Streptomyces sp. synthetic construct
Macromolecule	triostin A (protein) DNA (5'-D(CPGPTPAPCPG)-3') (nucleic acid)
Unique Ligands	QUI