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232,829 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Jayathilaka, N."

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Search Summary

This query matches 2 Structures.

Refinements

Structure Determination Methodology

experimental (2)

Scientific Name of Source Organism

Homo sapiens (2)

Taxonomy

Eukaryota (2)

Experimental Method

X-RAY DIFFRACTION (2)

Polymer Entity Type

	DNA (2)
	Protein (2)

Refinement Resolution (Å)

	2.0 - 2.5 (1)
	2.5 - 3.0 (1)

Release Date

2010 - 2014 (2)

Symmetry Type

Cyclic (2)

SCOP Classification

Alpha and beta proteins (a+b) (2)

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1 to 2 of 2 Structures

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3KOV	Download File View File

Structure of MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors

Wu, Y., Dey, R., Han, A., Jayathilaka, N., Philips, M., Ye, J., Chen, L.

(2010) J Mol Biology 397: 520-533

Released	2010-02-16
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Myocyte-specific enhancer factor 2A (protein) DNA (5'-D(APAPCPTPAPTPTPTPAPTPAPAPG)-3') (nucleic acid) DNA (5'-D(TPCPTPTPAPTPAPAPAPTPAPGPT)-3') (nucleic acid)

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3MU6	Download File View File

Inhibiting the Binding of Class IIa Histone Deacetylases to Myocyte Enhancer Factor-2 by Small Molecules

Jayathilaka, N., Han, A., Gaffney, K., Dey, R., He, J., Ye, J., Gao, T., Petasis, N.A., Chen, L.

(2012) Nucleic Acids Res 40: 5378-5388

Released	2011-11-02
Method	X-RAY DIFFRACTION 2.434 Å
Organisms	Homo sapiens
Macromolecule	Myocyte-specific enhancer factor 2A (protein) DNA (5'-D(APAPAPGPCPTPAPTPTPAPTPTPAPGPCPTPT)-3') (nucleic acid) DNA (5'-D(TPAPAPGPCPTPAPAPTPAPAPTPAPGPCPTPT)-3') (nucleic acid)
Unique Ligands	BXL