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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Li, E."

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Search Summary

This query matches 45 Structures.

Refinements

Structure Determination Methodology

experimental (45)

Scientific Name of Source Organism

	Homo sapiens (20)
	Arabidopsis thaliana (5)
	Henipavirus nipahense (4)
	Linum usitatissimum (4)
	Rattus norvegicus (4)
	DNA molecule (3)
	Macaca mulatta (3)
	Severe acute respiratory syndrome coronavirus 2 (3)
	synthetic construct (3)
	Bos taurus (2)

More...

Taxonomy

	Eukaryota (41)
	Riboviria (9)
	other sequences (3)
	unclassified sequences (3)

Experimental Method

	X-RAY DIFFRACTION (26)
	ELECTRON MICROSCOPY (13)
	SOLUTION NMR (6)

Polymer Entity Type

	Protein (45)
	RNA (5)
	DNA (3)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (8)
	2.0 - 2.5 (9)
	2.5 - 3.0 (7)
	3.0 - 3.5 (10)
	3.5 - 4.0 (3)
	4.0 - 4.5 (1)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (5)
	2010 - 2014 (4)
	2015 - 2019 (12)
	2020 - 2024 (21)
	2025 - 2029 (2)

Enzyme Classification Name

	Transferases (22)
	Hydrolases (4)

Symmetry Type

	Asymmetric (38)
	Cyclic (7)

SCOP Classification

	All beta proteins (4)
	Alpha and beta proteins (a+b) (3)
	Alpha and beta proteins (a/b) (1)

AllSelected

1 to 25 of 45 Structures

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1B4M \| pdb_00001b4m	Download File View File

NMR STRUCTURE OF APO CELLULAR RETINOL-BINDING PROTEIN II, 24 STRUCTURES

Lu, J., Lin, C.-L., Tang, C., Ponder, J.W., Kao, J.L.F., Cistola, D.P., Li, E.

(1999) J Mol Biology 286: 1179-1195

Released	1999-04-27
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	CELLULAR RETINOL-BINDING PROTEIN II (protein)

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1EII \| pdb_00001eii	Download File View File

NMR STRUCTURE OF HOLO CELLULAR RETINOL-BINDING PROTEIN II

Lu, J., Lin, C.L., Tang, C., Ponder, J.W., Kao, J.L., Cistola, D.P., Li, E.

(2000) J Mol Biology 300: 619-632

Released	2000-08-09
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	CELLULAR RETINOL-BINDING PROTEIN II (protein)
Unique Ligands	RTL

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1F03 \| pdb_00001f03	Download File View File

SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C

Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.

(2001) Eur J Biochem 268: 1620-1630

Released	2000-06-21
Method	SOLUTION NMR
Organisms	Bos taurus
Macromolecule	CYTOCHROME B5 (protein)
Unique Ligands	HEM

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1F04 \| pdb_00001f04	Download File View File

SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C

Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.

(2001) Eur J Biochem 268: 1620-1630

Released	2000-06-21
Method	SOLUTION NMR
Organisms	Bos taurus
Macromolecule	CYTOCHROME B5 (protein)
Unique Ligands	HEM

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1MX7 \| pdb_00001mx7	Download File View File

Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility

Lu, J., Cistola, D.P., Li, E.

(2003) J Mol Biology 330: 799-812

Released	2003-07-29
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	CELLULAR RETINOL-BINDING PROTEIN I, APO (protein)

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1MX8 \| pdb_00001mx8	Download File View File

Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility

Lu, J., Cistola, D.P., Li, E.

(2003) J Mol Biology 330: 799-812

Released	2003-07-29
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	CELLULAR RETINOL-BINDING PROTEIN I, HOLO (protein)
Unique Ligands	RTL

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3T9T \| pdb_00003t9t	Download File View File

Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline

Han, S., Caspers, N.

(2011) Bioorg Med Chem Lett 21: 6258-6263

Released	2011-10-12
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Tyrosine-protein kinase ITK/TSK (protein)
Unique Ligands	GOL, IAQ

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3TG4 \| pdb_00003tg4	Download File View File

Structure of SMYD2 in complex with SAM

Zhao, K., Wang, L.

(2011) J Biological Chem

Released	2011-08-31
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	N-lysine methyltransferase SMYD2 (protein)
Unique Ligands	GOL, SAM, ZN

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3TG5 \| pdb_00003tg5	Download File View File

Structure of SMYD2 in complex with p53 and SAH

Zhao, K., Wang, L.

(2011) J Biological Chem

Released	2011-08-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Cellular tumor antigen p53 (protein) N-lysine methyltransferase SMYD2 (protein)
Unique Ligands	GOL, SAH, ZN

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4QQN \| pdb_00004qqn	Download File View File

Protein arginine methyltransferase 3 in complex with compound MTV044246

Dong, A., Dobrovetsky, E., Tempel, W., He, H., Zhao, K., Smil, D., Landon, M., Luo, X., Chen, Z., Dai, M., Yu, Z., Lin, Y., Zhang, H., Zhao, K., Schapira, M., Brown, P.J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Structural Genomics Consortium (SGC)

(2018) J Med Chem 61: 1204-1217

Released	2014-09-17
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Homo sapiens
Macromolecule	PRMT3 protein (protein)
Unique Ligands	3BQ, CL, GOL, UNX

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5GSA \| pdb_00005gsa	Download File View File

EED in complex with an allosteric PRC2 inhibitor

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) Nat Chem Biol 13: 381-388

Released	2017-02-01
Method	X-RAY DIFFRACTION 2.49 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	73K

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5H13 \| pdb_00005h13	Download File View File

EED in complex with PRC2 allosteric inhibitor EED396

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) PLoS One 12: e0169855-e0169855

Released	2017-01-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Polycomb protein EED (protein)
Unique Ligands	GOL, LQA, PR

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5H14 \| pdb_00005h14	Download File View File

EED in complex with an allosteric PRC2 inhibitor EED666

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) PLoS One 12: e0169855-e0169855

Released	2017-01-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	GOL, LQB

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5H15 \| pdb_00005h15	Download File View File

EED in complex with PRC2 allosteric inhibitor EED709

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) PLoS One 12: e0169855-e0169855

Released	2017-01-25
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	LQD

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5H17 \| pdb_00005h17	Download File View File

EED in complex with PRC2 allosteric inhibitor EED210

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) PLoS One 12: e0169855-e0169855

Released	2017-01-25
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	LQE

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5H19 \| pdb_00005h19	Download File View File

EED in complex with PRC2 allosteric inhibitor EED162

Zhao, K., Zhao, M., Luo, X., Zhang, H.

(2017) PLoS One 12: e0169855-e0169855

Released	2017-01-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	LQF

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5WUK \| pdb_00005wuk	Download File View File

Crystal structure of EED [G255D] in complex with EZH2 peptide and EED226 compound

Chen, Z.

(2017) Anal Biochem 522: 37-45

Released	2017-05-03
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	73K, GOL

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5XJO \| pdb_00005xjo	Download File View File

Plant receptor ERL1-TMM in complex with peptide EPF1

Chai, J., Lin, G., Zhang, L., Han, Z., Shpak, E.D., Yang, X.

(2017) Genes Dev 31: 927-938

Released	2019-01-23
Method	X-RAY DIFFRACTION 2.626 Å
Organisms	Arabidopsis thaliana
Macromolecule	LRR receptor-like serine/threonine-protein kinase ERL1 (protein) Protein EPIDERMAL PATTERNING FACTOR 1 (protein) Protein TOO MANY MOUTHS (protein)

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5XJX \| pdb_00005xjx	Download File View File

Pre-formed plant receptor ERL1-TMM complex

Chai, J., Lin, G., Zhang, L., Han, Z., Yang, X., Liu, W., Qi, Y., Chang, J., Li, E.

(2017) Genes Dev 31: 927-938

Released	2019-01-23
Method	X-RAY DIFFRACTION 3.055 Å
Organisms	Arabidopsis thaliana
Macromolecule	LRR receptor-like serine/threonine-protein kinase ERL1 (protein) Protein TOO MANY MOUTHS (protein)

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5XKJ \| pdb_00005xkj	Download File View File

Crystal structure of plant receptor ERL1-TMM in complexe with EPF2

Chai, J., Lin, G.

(2017) Genes Dev 31: 927-938

Released	2019-01-23
Method	X-RAY DIFFRACTION 3.475 Å
Organisms	Arabidopsis thaliana
Macromolecule	LRR receptor-like serine/threonine-protein kinase ERL1 (protein) Protein EPIDERMAL PATTERNING FACTOR 2 (protein) Protein TOO MANY MOUTHS (protein)

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5XKN \| pdb_00005xkn	Download File View File

Crystal structure of plant receptor ERL2 in complexe with EPFL4

Chai, J., Lin, G.

(2017) Genes Dev 31: 927-938

Released	2019-01-23
Method	X-RAY DIFFRACTION 3.651 Å
Organisms	Arabidopsis thaliana
Macromolecule	EPIDERMAL PATTERNING FACTOR-like protein 4 (protein) LRR receptor-like serine/threonine-protein kinase ERL2 (protein)

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5XPI \| pdb_00005xpi	Download File View File

Structure of UHRF1 TTD in complex with NV01

Luo, X., Zhao, K.

(2018) SLAS Discov 23: 930-940

Released	2018-04-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase UHRF1 (protein)
Unique Ligands	8C3

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7QJG \| pdb_00007qjg	Download File View File

EED in complex with PRC2 allosteric inhibitor compound 6

Zhao, K., Zhao, M., Luo, X., Zhang, H., Scheufler, C.

(2022) J Med Chem 65: 5317-5333

Released	2022-04-13
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	CL, EKR

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7QJU \| pdb_00007qju	Download File View File

EED in complex with PRC2 allosteric inhibitor compound 7

Zhao, K., Zhao, M., Luo, X., Zhang, H., Scheufler, C.

(2022) J Med Chem 65: 5317-5333

Released	2022-04-13
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	CL, EKF

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7QK4 \| pdb_00007qk4	Download File View File

EED in complex with PRC2 allosteric inhibitor compound 22 (MAK683)

Zhao, K., Zhao, M., Luo, X., Zhang, H., Scheufler, C.

(2022) J Med Chem 65: 5317-5333

Released	2022-04-13
Method	X-RAY DIFFRACTION 1.602 Å
Organisms	Homo sapiens
Macromolecule	Histone-lysine N-methyltransferase EZH2 (protein) Polycomb protein EED (protein)
Unique Ligands	CL, EJR

1 to 25 of 45 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1B4M | pdb_00001b4m

1EII | pdb_00001eii

1F03 | pdb_00001f03

1F04 | pdb_00001f04

1MX7 | pdb_00001mx7

1MX8 | pdb_00001mx8

3T9T | pdb_00003t9t

3TG4 | pdb_00003tg4

3TG5 | pdb_00003tg5

4QQN | pdb_00004qqn

5GSA | pdb_00005gsa

5H13 | pdb_00005h13

5H14 | pdb_00005h14

5H15 | pdb_00005h15

5H17 | pdb_00005h17

5H19 | pdb_00005h19

5WUK | pdb_00005wuk

5XJO | pdb_00005xjo

5XJX | pdb_00005xjx

5XKJ | pdb_00005xkj

5XKN | pdb_00005xkn

5XPI | pdb_00005xpi

7QJG | pdb_00007qjg

7QJU | pdb_00007qju

7QK4 | pdb_00007qk4