RCSB PDB: Search

2P0K	Download File View File

Crystal structure of SCMH1

Herzanych, N., Senisterra, G., Liu, Y., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)

To be published

Released	2007-03-27
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	Polycomb protein SCMH1 (protein)
Unique Ligands	CL, PO4

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2QNR	Download File View File

Human septin 2 in complex with GDP

Rabeh, W.M., Nedyalkova, L., Tempel, W., Landry, R., Crombet, L., Kozieradzki, I., Senisterra, G., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2007-07-31
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Septin-2 (protein)
Unique Ligands	GDP, UNX

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3IEZ	Download File View File

Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2

Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2009-11-03
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Ras GTPase-activating-like protein IQGAP2 (protein)
Unique Ligands	UNX

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3ISU	Download File View File

Crystal structure of the RGC domain of IQGAP3

Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2009-09-22
Method	X-RAY DIFFRACTION 1.88 Å
Organisms	Homo sapiens
Macromolecule	Ras GTPase-activating-like protein IQGAP3 (protein)

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3IUF	Download File View File

Crystal structure of the C2H2-type zinc finger domain of human ubi-d4

Tempel, W., Xu, C., Bian, C., Adams-Cioaba, M., Eryilmaz, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)

(2011) Biochem Biophys Res Commun 413: 58-61

Released	2009-11-03
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Zinc finger protein ubi-d4 (protein)
Unique Ligands	ZN

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3KH0	Download File View File

Crystal structure of the Ras-association (RA) domain of RALGDS

Shen, Y., Tempel, W., Wang, H., Tong, Y., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2009-11-17
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Ral guanine nucleotide dissociation stimulator (protein)
Unique Ligands	UNX

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3KUZ	Download File View File

Crystal structure of the ubiquitin like domain of PLXNC1

Wang, H., Li, B., Tempel, W., Tong, Y., Guan, X., Zhong, N., Crombet, L., MacKenzie, F., Buck, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2009-12-08
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Plexin-C1 (protein)
Unique Ligands	UNX

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3L43	Download File View File

Crystal structure of the dynamin 3 GTPase domain bound with GDP

Yang, S., Tempel, W., Tong, Y., Nedyalkova, L., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2010-01-19
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Homo sapiens
Macromolecule	Dynamin-3 (protein)
Unique Ligands	GDP, UNX

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3L46	Download File View File

Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)

Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Wang, H., Guan, X., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2010-01-12
Method	X-RAY DIFFRACTION 1.482 Å
Organisms	Homo sapiens
Macromolecule	Protein ECT2 (protein)
Unique Ligands	UNX

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3LLU	Download File View File

Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C

Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Zhong, N., Guan, X., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2010-02-09
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	Ras-related GTP-binding protein C (protein)
Unique Ligands	GNP, MG, UNX

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3LWE	Download File View File

The crystal structure of MPP8

Li, Z., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e25104-e25104

Released	2010-03-02
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	M-phase phosphoprotein 8 (protein)

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3MPX	Download File View File

Crystal structure of the DH and PH-1 domains of human FGD5

Shen, Y., Nedyalkova, L., Tong, Y., Tempel, W., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2010-06-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	FYVE, RhoGEF and PH domain-containing protein 5 (protein)
Unique Ligands	UNX

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3N0T	Download File View File

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Crombet, L., Cossar, D., Pagannon, S., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hassell, A., Shewchuk, L., Haffner, C., Bochkarev, A., Structural Genomics Consortium (SGC)

To be published

Released	2010-07-21
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Homo sapiens
Macromolecule	Dipeptidyl peptidase 2 (protein)
Unique Ligands	OPY

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3O47	Download File View File

Crystal structure of ARFGAP1-ARF1 fusion protein

Wang, H., Tong, Y., Nedyalkova, L., Tempel, W., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2010-08-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1 (protein)
Unique Ligands	GDP, ZN

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3PFY	Download File View File

The catalytic domain of human OTUD5

Walker, J.R., Asinas, A.E., Crombet, L., Dong, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2010-12-15
Method	X-RAY DIFFRACTION 1.702 Å
Organisms	Homo sapiens
Macromolecule	OTU domain-containing protein 5 (protein)
Unique Ligands	PEG, PG4, SO4, UNX

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3PM8	Download File View File

CAD domain of PFF0520w, Calcium dependent protein kinase

Wernimont, A.K., Hutchinson, A., Lew, J., Chamberlain, K., MacKenzie, F., Loppnau, P., Cossar, D., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)

To be published

Released	2010-12-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Plasmodium falciparum K1
Macromolecule	Calcium-dependent protein kinase 2 (protein)
Unique Ligands	CA, CL, NA

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3Q3J	Download File View File

Crystal structure of plexin A2 RBD in complex with Rnd1

Wang, H., Tempel, W., Tong, Y., Guan, X., Shen, L., Buren, L., Zhang, N., Wernimont, A.K., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2011-01-12
Method	X-RAY DIFFRACTION 1.971 Å
Organisms	Homo sapiens
Macromolecule	Plexin-A2 (protein) Rho-related GTP-binding protein Rho6 (protein)
Unique Ligands	GNP, MG, UNX

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3Q5I	Download File View File

Crystal Structure of PBANKA_031420

Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)

To be published

Released	2011-06-01
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Plasmodium berghei
Macromolecule	Protein kinase (protein)
Unique Ligands	ANP, CA, MG

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3R93	Download File View File

Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide

Li, J., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e25104-e25104

Released	2011-04-06
Method	X-RAY DIFFRACTION 2.057 Å
Organisms	Homo sapiens
Macromolecule	H3K9Me3 peptide (protein) M-phase phosphoprotein 8 (protein)
Unique Ligands	UNX

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3RP9	Download File View File

Crystal Structure of the apo MapK from Toxoplasma Gondii, 25.m01780 or TGME49_007820

Wernimont, A.K., Crombet, L., Pizarro, J.C., Crowther, G.J., Van Voorhis, W.C., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Lin, Y.H., Structural Genomics Consortium (SGC)

To be published

Released	2011-06-15
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Toxoplasma gondii ME49
Macromolecule	Mitogen-activated protein kinase (protein)
Unique Ligands	SO4

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3RPX	Download File View File

Crystal structure of complement component 1, q subcomponent binding protein, C1QBP

Tempel, W., Tong, Y., Crombet, L., Shen, Y., Guan, X., Nedyalkova, L., Walker, J.R., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H., Structural Genomics Consortium (SGC)

To be published

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Complement component 1 Q subcomponent-binding protein (protein)
Unique Ligands	UNX

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3S6B	Download File View File

Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150

Wernimont, A.K., Artz, J.D., Crombet, L., Lew, J., Weadge, J., Tempel, W., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Hui, R., Hills, T., Structural Genomics Consortium (SGC)

To be published

Released	2011-06-29
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Plasmodium falciparum 3D7
Macromolecule	Methionine aminopeptidase (protein)
Unique Ligands	FE, GOL

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3SM9	Download File View File

Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist

Wernimont, A.K., Dong, A., Seitova, A., Crombet, L., Khutoreskaya, G., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Cossar, D., Dobrovetsky, E., Structural Genomics Consortium (SGC)

To be published

Released	2011-07-27
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Homo sapiens
Macromolecule	Metabotropic glutamate receptor 3 (protein)
Unique Ligands	CL, SO4, Z99

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3TLX	Download File View File

Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum

Wernimont, A.K., Loppnau, P., Crombet, L., Weadge, J., Perieteanu, A., Edwards, A.M., Arrowsmith, C.H., Park, H., Bountra, C., Hui, R., Amani, M., Structural Genomics Consortium (SGC)

To be published

Released	2011-10-26
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Plasmodium falciparum
Macromolecule	Adenylate kinase 2 (protein)
Unique Ligands	ADP, AMP, ATP, MG

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4NW2	Download File View File

Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229

Qin, S., Tempel, W., Xu, C., El Bakkouri, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)

(2014) Nat Commun 5: 3952-3952

Released	2014-01-29
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens Influenza A virus (A/swine/Henan/1/2010(H3N2))
Macromolecule	Chromodomain-helicase-DNA-binding protein 1 (protein) Nonstructural protein 1 (protein)
Unique Ligands	GOL, UNX

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