Structure Determination MethodologyScientific Name of Source OrganismRefinement Resolution (Å)Enzyme Classification NameMembrane Protein Annotation | Jaakola, V.-P., Griffith, M.T., Hanson, M.A., Cherezov, V., Chien, E.Y.T., Lane, J.R., Ijzerman, A.P., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) (2008) Science 322: 1211-1217 | Released | 2008-10-14 | | Method | X-RAY DIFFRACTION 2.6 Å | | Organisms | | | Macromolecule | | | Unique Ligands | SO4, STE, ZMA |
Liu, W., Chun, E., Thompson, A.A., Chubukov, P., Xu, F., Katritch, V., Han, G.W., Heitman, L.H., Ijzerman, A.P., Cherezov, V., Stevens, R.C., GPCR Network (GPCR) (2012) Science 337: 232-236 | Released | 2012-07-25 | | Method | X-RAY DIFFRACTION 1.8 Å | | Organisms | | | Macromolecule | | | Unique Ligands | CLR, NA, OLA, OLB, OLC, PEG, ZMA |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 1.72 Å | | Organisms | | | Macromolecule | | | Unique Ligands | CLR, NA, OLA, OLB, OLC, ZMA |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 1.9 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DY, CLR, NA, OLA, OLB, OLC |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.002 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DZ, CLR, HTO, NA, OLA, OLB, OLC |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.2 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DX, CLR, NA, OLA, OLB |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.1 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DV, CLR, NA, OLA, OLB, OLC |
Zheng, Y., Qin, L., Ortiz Zacarias, N.V., de Vries, H., Han, G.W., Gustavsson, M., Dabros, M., Zhao, C., Cherney, R.J., Carter, P., Stamos, D., Abagyan, R., Cherezov, V., Stevens, R.C., IJzerman, A.P., Heitman, L.H., Tebben, A., Kufareva, I., Handel, T.M. (2016) Nature 540: 458-461 | Released | 2016-12-14 | | Method | X-RAY DIFFRACTION 2.806 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 73R, OLC, SO4, VT5, ZN |
Verdon, G., Amelia, T., van Veldhoven, J., Falsini, M., Liu, R., Heitman, L., van Westen, G., Segala, E., Cheng, R., Cooke, R., van der Es, D., Ijzerman, A. (2021) J Med Chem 64: 3827-3842 | Released | 2021-04-07 | | Method | X-RAY DIFFRACTION 3.119 Å | | Organisms | | | Macromolecule | | | Unique Ligands | CLR, NA, OLA, RVZ |
|
