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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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Search Summary

This query matches 178 Structures.

Refinements

Structure Determination Methodology

experimental (178)

Scientific Name of Source Organism

	Homo sapiens (92)
	synthetic construct (70)
	Mus musculus (11)
	Hirudo medicinalis (10)
	Gallus gallus (7)
	Brevibacillus brevis (5)
	Helianthus annuus (5)
	Rattus norvegicus (4)
	Staphylococcus aureus (4)
	Lama glama (3)

More...

Taxonomy

	Eukaryota (122)
	other sequences (71)
	Bacteria (17)
	Eukaryota (eukaryotes) (9)
	Riboviria (5)
	Archaea (2)
	unclassified sequences (2)
	Duplodnaviria (1)
	Riboviria (RNA viruses and viroids) (1)

Experimental Method

	X-RAY DIFFRACTION (125)
	SOLUTION NMR (28)
	ELECTRON MICROSCOPY (24)
	NEUTRON DIFFRACTION (1)
	POWDER DIFFRACTION (1)

Polymer Entity Type

Protein (178)

Refinement Resolution (Å)

	0.5 - 1.0 (9)
	1.0 - 1.5 (33)
	1.5 - 2.0 (38)
	2.0 - 2.5 (26)
	2.5 - 3.0 (29)
	3.0 - 3.5 (12)
	3.5 - 4.0 (1)
	4.0 - 4.5 (1)

Release Date

	1990 - 1994 (14)
	1995 - 1999 (4)
	2000 - 2004 (4)
	2005 - 2009 (19)
	2010 - 2014 (23)
	2015 - 2019 (44)
	2020 - 2024 (69)
	2025 - 2029 (1)

Enzyme Classification Name

	Hydrolases (41)
	Transferases (6)
	Ligases (1)

Membrane Protein Annotation

	PDBTM (20)
	mpstruc (18)
	OPM (16)
	MemProtMD (11)

Symmetry Type

	Asymmetric (144)
	Cyclic (19)

SCOP Classification

	All beta proteins (20)
	Artifacts (8)
	Peptides (7)
	Small proteins (5)
	Alpha and beta proteins (a+b) (2)
	Designed proteins (2)
	Alpha and beta proteins (a/b) (1)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 178 Structures

Page 1 of 8

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1ABI \| pdb_00001abi	Download File View File

STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS

Qiu, X., Tulinsky, A.

(1992) Biochemistry 31: 11689-11697

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) HIRULOG 3 (protein)

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1B0Q \| pdb_00001b0q	Download File View File

DITHIOL ALPHA MELANOTROPIN PEPTIDE CYCLIZED VIA RHENIUM METAL COORDINATION

Giblin, M.F., Wang, N., Hoffman, T.J., Jurisson, S.S., Quinn, T.P.

(1998) Proc Natl Acad Sci U S A 95: 12814-12818

Released	1998-11-18
Method	SOLUTION NMR
Macromolecule	PROTEIN (CYCLIC ALPHA MELANOCYTE STIMULATING HORMONE) (protein)
Unique Ligands	RE

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1BFW \| pdb_00001bfw	Download File View File

RETRO-INVERSO ANALOGUE OF THE G-H LOOP OF VP1 IN FOOT-AND-MOUTH-DISEASE (FMD) VIRUS, NMR, 10 STRUCTURES

Petit, M.C., Benkirane, N., Guichard, G., Phan Chan Du, A., Cung, M.T., Briand, J.P., Muller, S.

(1999) J Biological Chem 274: 3686-3692

Released	1999-01-13
Method	SOLUTION NMR
Macromolecule	VP1 PROTEIN (protein)

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1GO9 \| pdb_00001go9	Download File View File

Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.

Spyroulias, G.A., Papazacharias, S., Pairas, G., Cordopatis, P.

(2002) Eur J Biochem 269: 6009

Released	2001-10-31
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	CORTICOTROPIN RELEASING HORMONE (protein)

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1GOE \| pdb_00001goe	Download File View File

Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.

Spyroulias, G.A., Papazacharias, S., Pairas, G., Cordopatis, P.

(2002) Eur J Biochem 269: 6009

Released	2001-10-31
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	CORTICOTROPIN RELEASING HORMONE (protein)

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1IHS \| pdb_00001ihs	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6

Zdanov, A., Cygler, M.

(1993) Proteins 17: 252-265

Released	1994-01-31
Method	X-RAY DIFFRACTION 2 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) HIRUTONIN (protein)

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1IHT \| pdb_00001iht	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6

Zdanov, A., Cygler, M.

(1993) Proteins 17: 252-265

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) HIRUTONIN-6 (protein)

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1MCB \| pdb_00001mcb	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) (protein) PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH (protein)

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1MCC \| pdb_00001mcc	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) (protein) PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-NH2 (protein)

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1MCD \| pdb_00001mcd	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION
Organisms	Homo sapiens synthetic construct
Macromolecule	Immunoglobulin lambda-1 light chain (protein) PEPTIDE N-ACETYL-D-PHE-B-ALA-L-HIS-D-PRO-NH2 (protein)

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1MCE \| pdb_00001mce	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	Immunoglobulin lambda-1 light chain (protein) PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-OH (protein)

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1MCF \| pdb_00001mcf	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	Immunoglobulin lambda-1 light chain (protein) PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH (protein)

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1MCI \| pdb_00001mci	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) (protein) PEPTIDE N-ACETYL-D-PHE-L-HIS-D-PRO-OH (protein)

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1MCS \| pdb_00001mcs	Download File View File

PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS

Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.

(1993) Proteins 16: 246-267

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) (protein) PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH (protein)

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1NRQ \| pdb_00001nrq	Download File View File

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES

Tulinsky, A., Mathews, I.I.

(1994) Biochemistry 33: 3266-3279

Released	1994-05-31
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) RECEPTOR BASED PEPTIDE D-FPR'S (protein)

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1PXQ \| pdb_00001pxq	Download File View File

Structure of Subtilisin A

Kawulka, K.E., Sprules, T., McKay, R.T., Mercier, P., Diaper, C.M., Zuber, P., Vederas, J.C.

(2004) Biochemistry 43: 3385-3395

Released	2004-06-22
Method	SOLUTION NMR
Organisms	Bacillus subtilis
Macromolecule	Subtilisin A (protein)

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1SOC \| pdb_00001soc	Download File View File

NMR STUDY OF THE BACKBONE CONFORMATIONAL EQUILIBRIA OF SANDOSTATIN, MINIMIZED AVERAGE BETA-SHEET STRUCTURE

Melacini, G., Zhu, Q., Goodman, M.

(1997) Biochemistry 36: 1233-1241

Released	1997-04-21
Method	SOLUTION NMR
Macromolecule	SANDOSTATIN (protein)

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1TK2 \| pdb_00001tk2	Download File View File

Crystal Structure of the Complex formed between Alkaline Proteinase Savinase and Gramicidin S at 1.5A Resolution

Bhatt, V.S., Kaur, P., Klupsch, S., Betzel, C., Brenner, S., Singh, T.P.

To be published

Released	2004-06-22
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Brevibacillus brevis Lederbergia lenta
Macromolecule	GRAMICIDIN S (protein) SUBTILISIN SAVINASE (protein)
Unique Ligands	CA

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1TMB \| pdb_00001tmb	Download File View File

MOLECULAR BASIS FOR THE INHIBITION OF HUMAN ALPHA-THROMBIN BY THE MACROCYCLIC PEPTIDE CYCLOTHEONAMIDE A

Qiu, X., Padmanabhan, K.P., Maryanoff, B.E., Tulinsky, A.

(1993) Proc Natl Acad Sci U S A 90: 8048-8052

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Hirudo medicinalis Homo sapiens Theonella sp.
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) HIRUGEN (protein) cyclotheonamide A (protein)

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1TMT \| pdb_00001tmt	Download File View File

CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS

Priestle, J.P., Gruetter, M.G.

(1993) Protein Sci 2: 1630-1642

Released	1994-09-30
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) CGP 50,856 INHIBITOR, cleaved C-terminal hirudin fragment (protein) CGP 50,856 INHIBITOR, cleaved N-terminal tripeptide fragment, d-Phe-Pro-Arg (protein)
Unique Ligands	NAG

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1YL8 \| pdb_00001yl8	Download File View File

3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO

Spyroulias, G.A., Galanis, A.S., Petrou, C., Vahliotis, D., Sotiriou, P., Nikolopoulou, A., Nock, B., Maina, T., Cordopatis, P.

(2005) Med Chem 1: 487-499

Released	2005-09-20
Method	SOLUTION NMR
Macromolecule	[Tyr3]Octreotate peptide (protein)

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1YL9 \| pdb_00001yl9	Download File View File

3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO

Spyroulias, G.A., Galanis, A.S., Petrou, C., Vahliotis, D., Sotiriou, P., Nikolopoulou, A., Nock, B., Maina, T., Cordopatis, P.

(2005) Med Chem 1: 487-499

Released	2005-09-20
Method	SOLUTION NMR
Macromolecule	[Tyr3]Octreotate (protein)
Unique Ligands	CH4

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2HGT \| pdb_00002hgt	Download File View File

STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN

Tulinsky, A., Carperos, V.

(1991) J Mol Biology 221: 1379-1393

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (LARGE SUBUNIT) (protein) ALPHA-THROMBIN (SMALL SUBUNIT) (protein) Hirulog (protein)