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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "CHAPERONE PROTEIN"

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Search Summary

This query matches 30 Structures.

Refinements

Structure Determination Methodology

experimental (30)

Scientific Name of Source Organism

	Homo sapiens (10)
	Saccharomyces cerevisiae (3)
	Bos taurus (2)
	Caenorhabditis elegans (2)
	Escherichia coli (2)
	Escherichia coli K-12 (2)
	Escherichia coli O157:H7 (2)
	Acinetobacter baumannii (1)
	Arabidopsis thaliana (1)
	Bacillus subtilis (1)

More...

Taxonomy

	Eukaryota (21)
	Bacteria (9)

Experimental Method

	X-RAY DIFFRACTION (26)
	SOLUTION NMR (4)

Polymer Entity Type

Protein (30)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (5)
	2.0 - 2.5 (12)
	2.5 - 3.0 (4)
	3.0 - 3.5 (1)
	3.5 - 4.0 (2)

Release Date

	1990 - 1994 (3)
	1995 - 1999 (3)
	2005 - 2009 (6)
	2010 - 2014 (7)
	2015 - 2019 (11)

Enzyme Classification Name

Hydrolases (13)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (28)
	Cyclic (4)

SCOP Classification

	Alpha and beta proteins (a+b) (15)
	Artifacts (9)
	All beta proteins (3)
	Alpha and beta proteins (a/b) (3)
	All alpha proteins (1)

AllSelected

1 to 25 of 30 Structures

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1ATR \| pdb_00001atr	Download File View File

THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS

O'Brien, M.C., Mckay, D.B.

(1993) J Biological Chem 268: 24323-24329

Released	1993-10-31
Method	X-RAY DIFFRACTION 2.34 Å
Organisms	Bos taurus
Macromolecule	HEAT-SHOCK COGNATE 70 KD PROTEIN (protein)
Unique Ligands	ADP, MG, PO4

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1ATS \| pdb_00001ats	Download File View File

THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS

O'Brien, M.C., Mckay, D.B.

(1993) J Biological Chem 268: 24323-24329

Released	1993-10-31
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Bos taurus
Macromolecule	HEAT-SHOCK COGNATE 70 KD PROTEIN (protein)
Unique Ligands	ADP, MG

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1YER \| pdb_00001yer	Download File View File

HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION

Stebbins, C.E., Russo, A.A., Pavletich, N.P.

(1997) Cell 89: 239-250

Released	1998-04-22
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	HEAT SHOCK PROTEIN 90 (protein)

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1YES \| pdb_00001yes	Download File View File

HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "OPEN" CONFORMATION

Stebbins, C.E., Russo, A.A., Pavletich, N.P.

(1997) Cell 89: 239-250

Released	1998-04-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	HEAT SHOCK PROTEIN 90 (protein)

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1YET \| pdb_00001yet	Download File View File

GELDANAMYCIN BOUND TO THE HSP90 GELDANAMYCIN-BINDING DOMAIN

Stebbins, C.E., Russo, A.A., Pavletich, N.P.

(1997) Cell 89: 239-250

Released	1998-04-22
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	HEAT SHOCK PROTEIN 90 (protein)
Unique Ligands	GDM

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3DPA \| pdb_00003dpa	Download File View File

CRYSTAL STRUCTURE OF CHAPERONE PROTEIN PAPD REVEALS AN IMMUNOGLOBULIN FOLD

Holmgren, A., Branden, C.-I.

(1989) Nature 342: 248-251

Released	1991-10-15
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	CHAPERONE PROTEIN PAPD (protein)

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5LQ9 \| pdb_00005lq9	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR200323.

Vallee, F., Dupuy, A.

To be published

Released	2017-08-23
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	72K

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5LR1 \| pdb_00005lr1	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH A003498614A.

Vallee, F., Dupuy, A.

To be published

Released	2017-08-23
Method	X-RAY DIFFRACTION 1.44 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	72Y

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5LR7 \| pdb_00005lr7	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530

Vallee, F., Dupuy, A.

To be published

Released	2017-08-23
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	73J

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5LRL \| pdb_00005lrl	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH A003492875

Vallee, F., Dupuy, A.

(2019) J Chem Inf Model 59: 5135-5147

Released	2017-08-23
Method	X-RAY DIFFRACTION 1.33 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	73S

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5LRZ \| pdb_00005lrz	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH A003643501

Vallee, F., Dupuy, A.

To be published

Released	2017-09-13
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	73Y

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5LS1 \| pdb_00005ls1	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR166475

Vallee, F., Dupuy, A.

To be published

Released	2017-08-02
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	73Z

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5T21 \| pdb_00005t21	Download File View File

CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR148019.

Vallee, F., Dupuy, A.

To be published

Released	2017-08-23
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Heat shock protein HSP 90-alpha (protein)
Unique Ligands	74E

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1R6Q \| pdb_00001r6q	Download File View File

ClpNS with fragments

Xia, D., Maurizi, M.R., Guo, F., Singh, S.K., Esser, L.

(2004) J Struct Biol 146: 166-179

Released	2005-02-15
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Escherichia coli
Macromolecule	ATP-dependent Clp protease ATP-binding subunit clpA (protein) ATP-dependent Clp protease adaptor protein clpS (protein)
Unique Ligands	GOL, Y1, YBT

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2B26 \| pdb_00002b26	Download File View File

The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1

Li, J., Wu, Y., Qian, X., Sha, B.

(2006) Biochem J 398: 353-360

Released	2006-09-19
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Drosophila melanogaster Saccharomyces cerevisiae
Macromolecule	Heat shock 70 kDa protein cognate 2 (protein) SIS1 protein (protein)

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2GUZ \| pdb_00002guz	Download File View File

Structure of the Tim14-Tim16 complex of the mitochondrial protein import motor

Mokranjac, D., Bourenkov, G., Hell, K., Neupert, W., Groll, M.

(2006) EMBO J 25: 4675-4685

Released	2006-10-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Mitochondrial import inner membrane translocase subunit TIM14 (protein) Mitochondrial import inner membrane translocase subunit TIM16 (protein)
Unique Ligands	FLC

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2K77 \| pdb_00002k77	Download File View File

NMR solution structure of the Bacillus subtilis ClpC N-domain

Kojetin, D.J., McLaughlin, P.D., Thompson, R.J., Rance, M., Cavanagh, J.

(2009) J Mol Biology 387: 639-652

Released	2009-04-28
Method	SOLUTION NMR
Organisms	Bacillus subtilis
Macromolecule	Negative regulator of genetic competence clpC/mecB (protein)

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2NA4 \| pdb_00002na4	Download File View File

Curli secretion specificity factor CsgE W48A/F79A mutant

Shu, Q., Krezel, A.M., Frieden, C.

(2016) Proc Natl Acad Sci U S A 113: 7130-7135

Released	2016-06-15
Method	SOLUTION NMR
Organisms	Escherichia coli K-12
Macromolecule	Curli production assembly/transport component CsgE (protein)

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2XCM \| pdb_00002xcm	Download File View File

COMPLEX OF HSP90 N-TERMINAL, SGT1 CS AND RAR1 CHORD2 DOMAIN

Zhang, M., Pearl, L.H.

(2010) Mol Cell 39: 269

Released	2010-08-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Arabidopsis thaliana Hordeum vulgare
Macromolecule	CYTOSOLIC HEAT SHOCK PROTEIN 90 (protein) RAR1 (protein) SGT1-LIKE PROTEIN (protein)
Unique Ligands	ADP, MG, ZN

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3AJI \| pdb_00003aji	Download File View File

Structure of Gankyrin-S6ATPase photo-cross-linked site-specifically, and incoporated by genetic code expansion

Sato, S., Mimasu, S., Sato, A., Hino, N., Sakamoto, K., Umehara, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2011) Biochemistry 50: 250-257

Released	2010-12-22
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Mus musculus
Macromolecule	26S proteasome non-ATPase regulatory subunit 10 (protein) Proteasome (Prosome, macropain) 26S subunit, ATPase, 4 (protein)

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3BLC \| pdb_00003blc	Download File View File

Crystal structure of the periplasmic domain of the Escherichia Coli YIDC

Paetzel, M., Oliver, D.C.

(2008) J Biological Chem 283: 5208-5216

Released	2007-12-25
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	Inner membrane protein oxaA (protein)

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3HFD \| pdb_00003hfd	Download File View File

Nucleosome Assembly Protein 1 from Plasmodium knowlesi

Arakaki, T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)

To be published

Released	2009-05-26
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Plasmodium knowlesi strain H
Macromolecule	Nucleosome assembly protein 1 (protein)

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3QML \| pdb_00003qml	Download File View File

The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor

Yan, M., Li, J.Z., Sha, B.D.

(2011) Biochem J 438: 447-455

Released	2011-06-29
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	78 kDa glucose-regulated protein homolog (protein) Nucleotide exchange factor SIL1 (protein)
Unique Ligands	MG, PO4

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3VLF \| pdb_00003vlf	Download File View File

Crystal structure of yeast proteasome interacting protein

Takagi, K., Kim, S., Kato, K., Tanaka, K., Saeki, Y., Mizushima, T.

(2012) J Biological Chem 287: 12172-12182

Released	2012-02-22
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	26S protease regulatory subunit 7 homolog (protein) DNA mismatch repair protein HSM3 (protein)

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4I2W \| pdb_00004i2w	Download File View File

Crystal structure of the myosin chaperone UNC-45 from C.elegans in complex with a Hsp70 peptide

Clausen, T., Gazda, L., Hellerschmied, D.

(2013) Cell 152: 183-195

Released	2013-03-13
Method	X-RAY DIFFRACTION 3.6 Å
Organisms	Caenorhabditis elegans
Macromolecule	Heat shock 70 kDa protein A (protein) Protein UNC-45 (protein)

1 to 25 of 30 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1ATR | pdb_00001atr

1ATS | pdb_00001ats

1YER | pdb_00001yer

1YES | pdb_00001yes

1YET | pdb_00001yet

3DPA | pdb_00003dpa

5LQ9 | pdb_00005lq9

5LR1 | pdb_00005lr1

5LR7 | pdb_00005lr7

5LRL | pdb_00005lrl

5LRZ | pdb_00005lrz

5LS1 | pdb_00005ls1

5T21 | pdb_00005t21

1R6Q | pdb_00001r6q

2B26 | pdb_00002b26

2GUZ | pdb_00002guz

2K77 | pdb_00002k77

2NA4 | pdb_00002na4

2XCM | pdb_00002xcm

3AJI | pdb_00003aji

3BLC | pdb_00003blc

3HFD | pdb_00003hfd

3QML | pdb_00003qml

3VLF | pdb_00003vlf

4I2W | pdb_00004i2w