Download MendeleyCrystal structure of human FPPS in complex with one magnesium ion
Park, J., Berghuis, A.M.To be published.
4XQS
Crystal structure of human FPPS in complex with one magnesium ion
- PDB DOI: https://doi.org/10.2210/pdb4XQS/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2015-01-20 Released: 2016-01-20
- Funding Organization(s): Fonds de recherche Nature et technologies
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.232
- R-Value Work: 0.192
- R-Value Observed: 0.195
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Farnesyl pyrophosphate synthase | A [auth F] | 375 | Homo sapiens | Mutation(s): 0 Gene Names: FDPS, FPS, KIAA1293 EC: 2.5.1.10 (PDB Primary Data), 2.5.1.1 (PDB Primary Data) |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P14324 (Homo sapiens) Explore P14324 Go to UniProtKB: P14324 | |||||
PHAROS: P14324 GTEx: ENSG00000160752 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P14324 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | C [auth F], D [auth F] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| MG Query on MG | B [auth F] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.232
- R-Value Work: 0.192
- R-Value Observed: 0.195
- Space Group: P 41 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 110.77 | α = 90 |
| b = 110.77 | β = 90 |
| c = 76.97 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2016-01-20 Deposition Author(s): Park, J., Berghuis, A.M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Fonds de recherche Nature et technologies | Canada | -- |
Revision History (Full details and data files)
- Version 1.0: 2016-01-20
Type: Initial release - Version 1.1: 2023-09-27
Changes: Data collection, Database references, Derived calculations, Refinement description
