Download MendeleyCrystal structure of the tetrameric wt GluA2 ligand-binding domain bound to glutamate at 1.45 Angstroms resolution
Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Ghisi, V., Faelber, K., Lau, A.Y., Daumke, O., Plested, A.J.R.To be published.
4Z0I
Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution
- PDB DOI: https://doi.org/10.2210/pdb4Z0I/pdb
- Classification: TRANSPORT PROTEIN
- Organism(s): Rattus norvegicus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2015-03-26 Released: 2016-01-13
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.208
- R-Value Work: 0.177
- R-Value Observed: 0.179
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 2.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glutamate receptor 2,Glutamate receptor 2 | 263 | Rattus norvegicus | Mutation(s): 0 Gene Names: Gria2, Glur2 |  | |
UniProt | |||||
Find proteins for P19491 (Rattus norvegicus) Explore P19491 Go to UniProtKB: P19491 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P19491 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PG4 Query on PG4 | G [auth A] | TETRAETHYLENE GLYCOL C8 H18 O5 UWHCKJMYHZGTIT-UHFFFAOYSA-N |  | ||
| GLU Query on GLU | C [auth A], I [auth B] | GLUTAMIC ACID C5 H9 N O4 WHUUTDBJXJRKMK-VKHMYHEASA-N |  | ||
| PEG Query on PEG | H [auth A] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N |  | ||
| PO4 Query on PO4 | D [auth A] E [auth A] F [auth A] J [auth B] K [auth B] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.208
- R-Value Work: 0.177
- R-Value Observed: 0.179
- Space Group: P 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 47.19 | α = 90 |
| b = 47.27 | β = 93.57 |
| c = 116.82 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| MOSFLM | data reduction |
| PHASER | phasing |
| Coot | model building |
| XDS | data reduction |
| XDS | data scaling |
Entry History
Deposition Data
- Released Date: 2016-01-13 Deposition Author(s): Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Ghisi, V., Faelber, K., Lau, A.Y., Daumke, O., Plested, A.J.R.
Revision History (Full details and data files)
- Version 1.0: 2016-01-13
Type: Initial release - Version 2.0: 2020-03-25
Changes: Atomic model, Derived calculations - Version 2.1: 2024-01-10
Changes: Data collection, Database references, Refinement description - Version 2.2: 2024-11-13
Changes: Structure summary
