1FYW
CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1fywa_ | Alpha and beta proteins (a/b) | Flavodoxin-like | Toll/Interleukin receptor TIR domain | Toll/Interleukin receptor TIR domain | Toll-like receptor 2, TLR2 | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.10140 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Toll/interleukin-1 receptor homology (TIR) domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01582 | TIR domain (TIR) | TIR domain | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001611 | Leucine-rich repeat | Repeat | |
IPR017241 | Toll-like receptor | Family | |
IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily | Homologous Superfamily | |
IPR000483 | Cysteine-rich flanking region, C-terminal | Domain | |
IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain | Domain | |
IPR003591 | Leucine-rich repeat, typical subtype | Repeat | |
IPR032675 | Leucine-rich repeat domain superfamily | Homologous Superfamily |