1HX5 | pdb_00001hx5

Crystal structure of M. tuberculosis chaperonin-10

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
G	d1hx5g_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
F	d1hx5f_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
E	d1hx5e_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
D	d1hx5d_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
C	d1hx5c_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
B	d1hx5b_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
A	d1hx5a_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
G	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroES-like	8056975	3000002	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
G	Cpn10	e1hx5G1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
F	Cpn10	e1hx5F1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
E	Cpn10	e1hx5E1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
D	Cpn10	e1hx5D1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
C	Cpn10	e1hx5C1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
B	Cpn10	e1hx5B1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
A	Cpn10	e1hx5A1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
G	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
F	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
E	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
D	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
C	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
B	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
A	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G	10 KDA CHAPERONIN	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding enzyme binding zymogen binding protein folding chaperone cation binding metal ion binding protein-folding chaperone binding	regulation of cellular process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation primary metabolic process regulation of cellular process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of gene expression biosynthetic process cellular process metabolic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process response to stimulus response to chemical response to antibiotic cellular response to stimulus cellular response to heat cellular response to stress response to stress response to heat response to abiotic stimulus response to temperature stimulus	cellular anatomical structure extracellular region intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane membrane external encapsulating structure cell wall peptidoglycan-based cell wall

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G	IPR018369	Chaperonin GroES, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G	IPR011032	GroES-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G	IPR037124	GroES chaperonin superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G	IPR020818	GroES chaperonin family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.