1JJ2

Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
--	PF00252	Ribosomal protein L16p/L10e (Ribosomal_L16)	Ribosomal protein L16p/L10e	-	Domain
--	PF00572	Ribosomal protein L13 (Ribosomal_L13)	Ribosomal protein L13	-	Family
--	PF00238	Ribosomal protein L14p/L23e (Ribosomal_L14)	Ribosomal protein L14p/L23e	-	Domain
--	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	-	Family
--	PF00827	Ribosomal L15 (Ribosomal_L15e)	Ribosomal L15	-	Family
--	PF17144	Ribosomal large subunit proteins 60S L5, and 50S L18 (Ribosomal_L5e)	Ribosomal large subunit proteins 60S L5, and 50S L18	-	Family
--	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	-	Family
--	PF01280	Ribosomal protein L19e (Ribosomal_L19e)	Ribosomal protein L19e	-	Family
--	PF01157	Ribosomal protein L21e (Ribosomal_L21e)	Ribosomal protein L21e	-	Family
--	PF00237	Ribosomal protein L22p/L17e (Ribosomal_L22)	Ribosomal protein L22p/L17e	This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.	Domain
--	PF00276	Ribosomal protein L23 (Ribosomal_L23)	Ribosomal protein L23	-	Family
--	PF16906	Ribosomal proteins L26 eukaryotic, L24P archaeal (Ribosomal_L26)	Ribosomal proteins L26 eukaryotic, L24P archaeal	-	Family
--	PF00467	KOW motif (KOW)	KOW motif	-	Family
--	PF00831	Ribosomal L29 protein (Ribosomal_L29)	Ribosomal L29 protein	-	Family
--	PF00327	Ribosomal protein L30p/L7e (Ribosomal_L30)	Ribosomal protein L30p/L7e	This family includes prokaryotic L30 and eukaryotic L7.	Domain
--	PF01655	Ribosomal protein L32 (Ribosomal_L32e)	Ribosomal protein L32	-	Family
--	PF01780	Ribosomal L37ae protein family (Ribosomal_L37ae)	Ribosomal L37ae protein family	-	Family
--	PF01907	Ribosomal protein L37e (Ribosomal_L37e)	Ribosomal protein L37e	-	Family
--	PF00832	Ribosomal L39 protein (Ribosomal_L39)	Ribosomal L39 protein	-	Family
--	PF03947	Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)	Ribosomal Proteins L2, C-terminal domain	-	Domain
--	PF00181	Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)	Ribosomal Proteins L2, RNA binding domain	-	Domain
--	PF00935	Ribosomal protein L44 (Ribosomal_L44)	Ribosomal protein L44	-	Family
--	PF00297	Ribosomal protein L3 (Ribosomal_L3)	Ribosomal protein L3	-	Family
--	PF00573	Ribosomal protein L4/L1 family (Ribosomal_L4)	Ribosomal protein L4/L1 family	-	Family
--	PF00281	Ribosomal protein L5 (Ribosomal_L5)	Ribosomal protein L5	-	Domain
--	PF00673	ribosomal L5P family C-terminus (Ribosomal_L5_C)	ribosomal L5P family C-terminus	This region is found associated with Pfam:PF00281.	Domain
--	PF00347	Ribosomal protein L6 (Ribosomal_L6)	Ribosomal protein L6	-	Domain
--	PF01248	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
--	23S RRNA	-	-	-
--	RIBOSOMAL PROTEIN L10E	RNA binding binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L13	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome rRNA binding	regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L14	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L15	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L15E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L18	RNA binding binding organic cyclic compound binding rRNA binding 5S rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L18E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L19E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L21E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
--	RIBOSOMAL PROTEIN L22	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	5S RRNA	-	-	-
--	RIBOSOMAL PROTEIN L23	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L24	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal large subunit biogenesis	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L24E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
--	RIBOSOMAL PROTEIN L29	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L30	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process ribosomal large subunit biogenesis macromolecule biosynthetic process nucleic acid metabolic process maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biosynthetic process cellular process metabolic process macromolecule metabolic process maturation of LSU-rRNA protein metabolic process translation	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L31E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L32E	DNA binding binding organic cyclic compound binding nucleic acid binding nucleoside phosphate binding nucleotide binding heterocyclic compound binding small molecule binding RNA binding rRNA binding structural molecule activity structural constituent of ribosome	cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair biosynthetic process cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair biosynthetic process protein metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L37Ae	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
--	RIBOSOMAL PROTEIN L37E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L39E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L2	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L44E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
--	RIBOSOMAL PROTEIN L3	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L4	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L5	RNA binding binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L6	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
--	RIBOSOMAL PROTEIN L7AE	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity structural molecule activity structural constituent of ribosome	RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process tRNA processing RNA 5'-end processing metabolic process RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process tRNA processing RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis protein metabolic process translation	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome
--	RIBOSOMAL PROTEIN L10	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular component organization or biogenesis ribosome assembly	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
--	IPR036920	Large ribosomal subunit protein uL16 superfamily	Homologous Superfamily
--	IPR022981	Large ribosomal subunit protein uL16, archaea	Family
--	IPR001197	Large ribosomal subunit protein uL16, eukaryotes/archaea	Family
--	IPR016180	Large ribosomal subunit protein uL16 domain	Domain
--	IPR047873	Large ribosomal subunit protein uL16	Family
--	IPR018255	Large ribosomal subunit protein uL16, conserved site, eukaryotes/archaea	Conserved Site
--	IPR023563	Large ribosomal subunit protein uL13, conserved site	Conserved Site
--	IPR005822	Large ribosomal subunit protein uL13	Family
--	IPR036899	Large ribosomal subunit protein uL13 superfamily	Homologous Superfamily
--	IPR005755	Large ribosomal subunit protein uL13, eukaryotic/archaeal	Family
--	IPR019971	Large ribosomal subunit protein uL14, archaeal	Family
--	IPR036853	Large ribosomal subunit protein uL14 superfamily	Homologous Superfamily
--	IPR000218	Large ribosomal subunit protein uL14	Family
--	IPR019972	Large ribosomal subunit protein uL14, conserved site	Conserved Site
--	IPR027386	Ribosomal uL15, N-terminal	Homologous Superfamily
--	IPR021131	Large ribosomal subunit protein uL15/eL18	Domain
--	IPR030878	Large ribosomal subunit protein uL15	Family
--	IPR001196	Large ribosomal subunit protein uL15, conserved site	Conserved Site
--	IPR036227	Large ribosomal subunit protein uL15/eL18 superfamily	Homologous Superfamily
--	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
--	IPR020925	Large ribosomal subunit protein eL15, conserved site	Conserved Site
--	IPR024794	Large ribosomal subunit protein eL15 core domain superfamily	Homologous Superfamily
--	IPR020926	Large ribosomal subunit protein eL15, archaeal	Family
--	IPR000439	Large ribosomal subunit protein eL15	Family
--	IPR005485	Large ribosomal subunit protein uL18 eukaryotic/archaeal	Family
--	IPR022947	Large ribosomal subunit protein eL18, archaea	Family
--	IPR021131	Large ribosomal subunit protein uL15/eL18	Domain
--	IPR021132	Large ribosomal subunit protein eL18, conserved site	Conserved Site
--	IPR001196	Large ribosomal subunit protein uL15, conserved site	Conserved Site
--	IPR000039	Large ribosomal subunit protein eL18	Family
--	IPR036227	Large ribosomal subunit protein uL15/eL18 superfamily	Homologous Superfamily
--	IPR015972	Large ribosomal subunit protein eL19, domain 1	Homologous Superfamily
--	IPR015974	Large ribosomal subunit protein eL19, domain 3	Homologous Superfamily
--	IPR039547	Large ribosomal subunit protein eL19	Family
--	IPR033936	Large ribosomal subunit protein eL19, archaeal	Domain
--	IPR023638	Large ribosomal subunit protein eL19, conserved site	Conserved Site
--	IPR035970	Large ribosomal subunit protein eL19 superfamily	Homologous Superfamily
--	IPR000196	Large ribosomal subunit protein eL19 domain	Domain
--	IPR015973	Large ribosomal subunit protein eL19, domain 2	Homologous Superfamily
--	IPR022856	Large ribosomal subunit protein eL21, archaeal	Family
--	IPR018259	Large ribosomal subunit protein eL21, conserved site	Conserved Site
--	IPR036948	Large ribosomal subunit protein eL21 superfamily	Homologous Superfamily
--	IPR001147	Large ribosomal subunit protein eL21	Family
--	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
--	IPR018260	Large ribosomal subunit protein uL22, conserved site	Conserved Site
--	IPR036394	Ribosomal protein uL22 superfamily	Homologous Superfamily
--	IPR001063	Large ribosomal subunit protein uL22	Family
--	IPR005721	Large ribosomal subunit protein uL22, eukaryotic/archaeal	Family
--	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
--	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
--	IPR019985	Large ribosomal subunit protein uL23	Family
--	IPR001014	Large ribosomal subunit protein uL23, conserved site	Conserved Site
--	IPR013025	Large ribosomal subunit protein uL23-like	Family
--	IPR041988	Large ribosomal subunit protein uL24, KOW domain	Domain
--	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
--	IPR005824	KOW	Domain
--	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
--	IPR005756	Large ribosomal subunit protein uL24, eukaryotic/archaeal	Family
--	IPR005825	Large ribosomal subunit protein uL24, conserved site	Conserved Site
--	IPR023438	Ribosomal_eL24	Unknown
--	IPR011017	TRASH domain	Domain
--	IPR000988	Large ribosomal subunit protein eL24-related, N-terminal	Domain
--	IPR023442	Large ribosomal subunit protein eL24, conserved site	Conserved Site
--	IPR038630	Ribosomal protein L24e/L24 superfamily	Homologous Superfamily
--	IPR050063	Universal ribosomal protein uL29	Family
--	IPR001854	Large ribosomal subunit protein uL29	Family
--	IPR036049	Large ribosomal subunit protein uL29 superfamily	Homologous Superfamily
--	IPR018254	Large ribosomal subunit protein uL29, conserved site	Conserved Site
--	IPR035808	Large ribosomal subunit protein uL30, eukaryotic/archaeal	Domain
--	IPR036919	Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamily	Homologous Superfamily
--	IPR039699	Large ribosomal subunit protein uL30	Family
--	IPR016082	Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain	Domain
--	IPR018038	Large ribosomal subunit protein uL30, conserved site	Conserved Site
--	IPR005997	Large ribosomal subunit protein uL30, archaeal	Family
--	IPR020052	Large ribosomal subunit protein eL31, conserved site	Conserved Site
--	IPR023621	Large ribosomal subunit protein eL31 domain superfamily	Homologous Superfamily
--	IPR000054	Large ribosomal subunit protein eL31	Family
--	IPR001515	Large ribosomal subunit protein eL32	Family
--	IPR018263	Large ribosomal subunit protein eL32, conserved site	Conserved Site
--	IPR036351	Large ribosomal subunit protein eL32 superfamily	Homologous Superfamily
--	IPR023654	Large ribosomal subunit protein eL32, archaeal	Family
--	IPR010995	DNA repair Rad51/transcription factor NusA, alpha-helical	Homologous Superfamily
--	IPR003583	Helix-hairpin-helix DNA-binding motif, class 1	Domain
--	IPR002674	Large ribosomal subunit protein eL43	Family
--	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
--	IPR011331	Large ribosomal subunit protein eL37/eL43	Homologous Superfamily
--	IPR050522	Eukaryotic ribosomal protein eL43	Family
--	IPR001569	Large ribosomal subunit protein eL37	Family
--	IPR018267	Large ribosomal subunit protein eL37, conserved site	Conserved Site
--	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
--	IPR011331	Large ribosomal subunit protein eL37/eL43	Homologous Superfamily
--	IPR023626	Large ribosomal subunit protein eL39 domain superfamily	Homologous Superfamily
--	IPR000077	Large ribosomal subunit protein eL39	Family
--	IPR020083	Large ribosomal subunit protein eL39, conserved site	Conserved Site
--	IPR022669	Large ribosomal subunit protein uL2, C-terminal	Domain
--	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
--	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
--	IPR023672	Large ribosomal subunit protein uL2, archaeal-type	Family
--	IPR022671	Large ribosomal subunit protein uL2, conserved site	Conserved Site
--	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
--	IPR022666	Large ribosomal subunit protein uL2, RNA-binding domain	Domain
--	IPR014726	Large ribosomal subunit protein uL2, domain 3	Homologous Superfamily
--	IPR002171	Large ribosomal subunit protein uL2	Family
--	IPR053708	Eukaryotic Ribosomal Large Subunit eL42	Homologous Superfamily
--	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
--	IPR000552	Large ribosomal subunit protein eL42	Family
--	IPR019926	Large ribosomal subunit protein uL3, conserved site	Conserved Site
--	IPR019928	Large ribosomal subunit protein uL3, archaeal	Family
--	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
--	IPR045077	Large ribosomal subunit protein uL3, archaeal/eukaryotic-type	Family
--	IPR044892	Ribosomal protein L3, domain 3, archaeal-type superfamily	Homologous Superfamily
--	IPR000597	Large ribosomal subunit protein uL3	Family
--	IPR019970	Large ribosomal subunit protein uL4, archaea	Family
--	IPR002136	Large ribosomal subunit protein uL4	Family
--	IPR013000	Large ribosomal subunit protein uL4, eukaryotic/archaeal, conserved site	Conserved Site
--	IPR045240	Large ribosomal subunit protein uL4, eukaryotic and archaeal type	Family
--	IPR023574	Large ribosomal subunit protein uL4 domain superfamily	Homologous Superfamily
--	IPR020929	Large ribosomal subunit protein uL5, conserved site	Conserved Site
--	IPR022803	Large ribosomal subunit protein uL5 domain superfamily	Homologous Superfamily
--	IPR022804	Large ribosomal subunit protein uL5, archaeal	Family
--	IPR031309	Large ribosomal subunit protein uL5, C-terminal	Domain
--	IPR031310	Large ribosomal subunit protein uL5, N-terminal	Domain
--	IPR002132	Large ribosomal subunit protein uL5	Family
--	IPR020040	Large ribosomal subunit protein uL6, alpha-beta domain	Domain
--	IPR019907	Large ribosomal subunit protein uL6, archaea	Family
--	IPR002359	Large ribosomal subunit protein uL6, conserved site-2	Conserved Site
--	IPR036789	Large ribosomal subunit protein uL6-like, alpha-beta domain superfamily	Homologous Superfamily
--	IPR000702	Large ribosomal subunit protein uL6-like	Family
--	IPR050257	Large ribosomal subunit protein eL8/uL1-like	Family
--	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
--	IPR022481	Large ribosomal subunit protein eL8, archaea	Family
--	IPR004037	Large ribosomal subunit protein eL8-like, conserved site	Conserved Site
--	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
--	IPR018492	Ribosomal protein eL8/Nhp2 family	Family
--	IPR043141	Large ribosomal subunit protein uL10-like domain superfamily	Homologous Superfamily
--	IPR001790	Large ribosomal subunit protein uL10	Family
--	IPR043164	Large ribosomal subunit protein uL10-like, insertion domain superfamily	Homologous Superfamily
--	IPR050323	Universal ribosomal protein uL10	Family
--	IPR040637	Large ribosomal subunit protein uL10-like, insertion domain	Domain
--	IPR022909	Large ribosomal subunit protein uL10, archaea	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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1JJ2

Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution

External Resource: Annotation

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage