1QFF

E. COLI FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) IN COMPLEX WITH BOUND FERRICHROME-IRON

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
--	PF00593	TonB dependent receptor-like, beta-barrel (TonB_dep_Rec_b-barrel)	TonB dependent receptor-like, beta-barrel	This entry represents the beta-barrel domain of TonB-dependent receptors, such as BtuB, CirA, FatA, FcuT, FecA, FepA, among others [1].	Domain
--	PF07715	TonB-dependent Receptor Plug Domain (Plug)	TonB-dependent Receptor Plug Domain	The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors ([1]). It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens ...	The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors ([1]). It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
--	FERRIC HYDROXAMATE UPTAKE RECEPTOR	protein binding binding protein domain specific binding molecular transducer activity signaling receptor activity cation binding transition metal ion binding iron ion binding ion binding metal ion binding small molecule binding toxic substance binding siderophore-iron transmembrane transporter activity siderophore uptake transmembrane transporter activity protein binding binding protein domain specific binding molecular transducer activity signaling receptor activity cation binding transition metal ion binding iron ion binding ion binding metal ion binding small molecule binding toxic substance binding siderophore-iron transmembrane transporter activity siderophore uptake transmembrane transporter activity transporter activity transmembrane transporter activity virion binding	intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis siderophore transport transport monoatomic ion transmembrane transport iron ion transport intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis siderophore transport transport monoatomic ion transmembrane transport iron ion transport iron ion transmembrane transport inorganic ion transmembrane transport establishment of localization metal ion transport inorganic cation transmembrane transport siderophore transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization transition metal ion transport monoatomic ion transport cellular process monoatomic cation transport iron coordination entity transport	cellular anatomical structure membrane protein-containing complex transmembrane transporter complex membrane protein complex transporter complex cell periphery cell outer membrane external encapsulating structure cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
--	IPR039426	TonB-dependent receptor-like	Family
--	IPR037066	TonB-dependent receptor, plug domain superfamily	Homologous Superfamily
--	IPR010917	TonB-dependent receptor, conserved site	Conserved Site
--	IPR010105	TonB-dependent siderophore receptor	Family
--	IPR036942	TonB-dependent receptor-like, beta-barrel domain superfamily	Homologous Superfamily
--	IPR012910	TonB-dependent receptor, plug domain	Domain
--	IPR010916	TonB box, conserved site	Conserved Site
--	IPR000531	TonB-dependent receptor-like, beta-barrel	Domain

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
--	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
--	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
--	mpstruc	TRANSMEMBRANE PROTEINS: BETA-BARREL	Beta-Barrel Membrane Proteins: Monomeric/Dimeric	FhuA-AW140-LPS

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.