Annotations: 1V06

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1v06a_	All beta proteins	AXH domain	AXH domain	automated matches	automated matches	MOUSE (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	AXH	e1v06A1	A: beta complex topology	X: Hedgehog/intein (From Homology)	H: Hedgehog/intein	T: AXH	F: AXH	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF08517	Ataxin-1 and HBP1 module (AXH) (AXH)	Ataxin-1 and HBP1 module (AXH)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	HMG BOX-CONTAINING PROTEIN 1	DNA binding binding nucleic acid binding RNA binding	developmental process regulation of biological process regulation of cellular process regulation of developmental process cellular developmental process negative regulation of developmental process macrophage derived foam cell differentiation biological regulation negative regulation of biological process regulation of cell differentiation negative regulation of macrophage derived foam cell differentiation foam cell differentiation cell differentiation negative regulation of cellular process regulation of macrophage derived foam cell differentiation developmental process regulation of biological process regulation of cellular process regulation of developmental process cellular developmental process negative regulation of developmental process macrophage derived foam cell differentiation biological regulation negative regulation of biological process regulation of cell differentiation negative regulation of macrophage derived foam cell differentiation foam cell differentiation cell differentiation negative regulation of cellular process regulation of macrophage derived foam cell differentiation negative regulation of cell differentiation cellular process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of gene expression biosynthetic process metabolic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process reactive oxygen species biosynthetic process negative regulation of metabolic process reactive oxygen species metabolic process regulation of reactive oxygen species biosynthetic process negative regulation of reactive oxygen species metabolic process negative regulation of reactive oxygen species biosynthetic process negative regulation of biosynthetic process regulation of reactive oxygen species metabolic process regulation of localization negative regulation of lipid transport transport regulation of transport lipid localization lipid transport negative regulation of transport regulation of lipid transport establishment of localization negative regulation of lipid localization localization regulation of lipid localization macromolecule localization cellular response to stimulus cell surface receptor signaling pathway response to stimulus signaling cell communication signal transduction Wnt signaling pathway	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR039655	HMG box-containing protein 1	Family
A	IPR009071	High mobility group box domain	Domain
A	IPR003652	Ataxin, AXH domain	Domain
A	IPR036096	Ataxin, AXH domain superfamily	Homologous Superfamily
A	IPR036910	High mobility group box domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.