2F3G | pdb_00002f3g

IIAGLC CRYSTAL FORM III

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d2f3gb_	All beta proteins	Barrel-sandwich hybrid	Duplicated hybrid motif	Glucose permease-like	Glucose-specific factor III (glsIII)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d2f3ga_	All beta proteins	Barrel-sandwich hybrid	Duplicated hybrid motif	Glucose permease-like	Glucose-specific factor III (glsIII)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Duplicated hybrid motif	8043117	3001927	SCOP2B (2022-06-29)
A	SCOP2 Family	Glucose permease-like	8030738	4002943	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Duplicated hybrid motif	8043117	3001927	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PTS_EIIA_1	e2f3gB1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Duplicated hybrid motif	F: PTS_EIIA_1	ECOD (1.6)
A	PTS_EIIA_1	e2f3gA1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Duplicated hybrid motif	F: PTS_EIIA_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.70.70.10	Mainly Beta	Distorted Sandwich	Glucose Permease (Domain IIA)	Glucose Permease (Domain IIA)	CATH (4.3.0)
A	2.70.70.10	Mainly Beta	Distorted Sandwich	Glucose Permease (Domain IIA)	Glucose Permease (Domain IIA)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00358	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PTS_EIIA_1)	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	GLUCOSE-SPECIFIC PHOSPHOCARRIER	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups cation binding ion binding binding metal ion binding small molecule binding	regulation of localization regulation of biological process regulation of transport transport regulation of maltose transport biological regulation negative regulation of biological process carbohydrate transport negative regulation of transport oligosaccharide transport establishment of localization negative regulation of maltose transport localization disaccharide transport regulation of localization regulation of biological process regulation of transport transport regulation of maltose transport biological regulation negative regulation of biological process carbohydrate transport negative regulation of transport oligosaccharide transport establishment of localization negative regulation of maltose transport localization disaccharide transport maltose transport import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system import across plasma membrane carbohydrate import across plasma membrane transmembrane transport cellular process carbohydrate transmembrane transport response to nutrient levels regulation of response to nutrient levels response to stimulus regulation of response to stimulus regulation of carbohydrate utilization carbohydrate utilization carbohydrate metabolic process regulation of cellular process negative regulation of metabolic process primary metabolic process regulation of primary metabolic process negative regulation of cellular process metabolic process regulation of carbohydrate metabolic process regulation of metabolic process negative regulation of carbohydrate metabolic process negative regulation of transmembrane transport regulation of transmembrane transport	cellular anatomical structure membrane protein-containing complex transmembrane transporter complex membrane protein complex transporter complex intracellular anatomical structure cytoplasm cytosol ATPase dependent transmembrane transport complex plasma membrane protein complex plasma membrane ATP-binding cassette (ABC) transporter complex cell periphery cellular anatomical structure membrane protein-containing complex transmembrane transporter complex membrane protein complex transporter complex intracellular anatomical structure cytoplasm cytosol ATPase dependent transmembrane transport complex plasma membrane protein complex plasma membrane ATP-binding cassette (ABC) transporter complex cell periphery enzyme IIA-maltose transporter complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR001127	Phosphotransferase system, sugar-specific permease EIIA type 1	Domain
A, B	IPR011055	Duplicated hybrid motif	Homologous Superfamily
A, B	IPR050890	Phosphotransferase system EIIA component	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.