2J4B | pdb_00002j4b

Crystal structure of Encephalitozoon cuniculi TAF5 N-terminal domain

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
E	d2j4be_	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	automated matches	(Encephalitozoon cuniculi ) [TaxId: 6035 ],	SCOPe (2.08)
D	d2j4bd_	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	automated matches	(Encephalitozoon cuniculi ) [TaxId: 6035 ],	SCOPe (2.08)
C	d2j4bc_	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	automated matches	(Encephalitozoon cuniculi ) [TaxId: 6035 ],	SCOPe (2.08)
B	d2j4bb_	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	automated matches	(Encephalitozoon cuniculi ) [TaxId: 6035 ],	SCOPe (2.08)
A	d2j4ba1	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	TAF5 subunit of TFIID	(Encephalitozoon cuniculi ) [TaxId: 6035 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
E	SCOP2B Superfamily	Taf5 N-terminal domain-like	8034622	3001495	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Taf5 N-terminal domain-like	8034622	3001495	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Taf5 N-terminal domain-like	8034622	3001495	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Taf5 N-terminal domain-like	8034622	3001495	SCOP2B (2022-06-29)
A	SCOP2 Family	Taf5 N-terminal domain-like	8022242	4002620	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Taf5 N-terminal domain-like	8034622	3001495	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
E	TFIID_NTD2	e2j4bE1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)
D	TFIID_NTD2	e2j4bD1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)
C	TFIID_NTD2	e2j4bC1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)
B	TFIID_NTD2	e2j4bB1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)
A	TFIID_NTD2	e2j4bA1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
E	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)
D	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)
C	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)
B	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)
A	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF04494	WD40 associated region in TFIID subunit, NTD2 domain (TFIID_NTD2)	WD40 associated region in TFIID subunit, NTD2 domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 72/90-100 KDA	general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity	RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process DNA-templated transcription initiation RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process transcription by RNA polymerase II biosynthetic process metabolic process RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process DNA-templated transcription initiation RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process transcription by RNA polymerase II biosynthetic process metabolic process cellular process macromolecule metabolic process transcription initiation at RNA polymerase II promoter	RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle cellular anatomical structure nucleoplasm RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex transferase complex intracellular organelle lumen intracellular organelle cellular anatomical structure nucleoplasm catalytic complex intracellular membrane-bounded organelle transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen organelle RNA polymerase complex transcription factor TFIID complex DNA-directed RNA polymerase complex intracellular protein-containing complex nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR020472	PAC1/LIS1-like, WD-40 repeat	Repeat
A, B, C, D, E	IPR001680	WD40 repeat	Repeat
A, B, C, D, E	IPR007582	TFIID subunit TAF5, NTD2 domain	Domain
A, B, C, D, E	IPR019775	WD40 repeat, conserved site	Conserved Site
A, B, C, D, E	IPR037264	TFIID subunit TAF5, NTD2 domain superfamily	Homologous Superfamily
A, B, C, D, E	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
A, B, C, D, E	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.