2V9P | pdb_00002v9p

Crystal structure of papillomavirus E1 hexameric helicase DNA-free form

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UNK_F_TYPE	e2v9pA2	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
A	Polyoma_lg_T_C	e2v9pA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
B	UNK_F_TYPE	e2v9pB1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
B	Polyoma_lg_T_C	e2v9pB2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
C	UNK_F_TYPE	e2v9pC1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
C	Polyoma_lg_T_C	e2v9pC2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
D	UNK_F_TYPE	e2v9pD1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
D	Polyoma_lg_T_C	e2v9pD2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
E	UNK_F_TYPE	e2v9pE1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
E	Polyoma_lg_T_C	e2v9pE2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
F	UNK_F_TYPE	e2v9pF1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
F	Polyoma_lg_T_C	e2v9pF2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
G	UNK_F_TYPE	e2v9pG1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
G	Polyoma_lg_T_C	e2v9pG2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
H	UNK_F_TYPE	e2v9pH2	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
H	Polyoma_lg_T_C	e2v9pH1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
I	UNK_F_TYPE	e2v9pI1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
I	Polyoma_lg_T_C	e2v9pI2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
J	UNK_F_TYPE	e2v9pJ1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
J	Polyoma_lg_T_C	e2v9pJ2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
K	UNK_F_TYPE	e2v9pK1	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
K	Polyoma_lg_T_C	e2v9pK2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)
L	UNK_F_TYPE	e2v9pL2	A: alpha arrays	X: N-terminal domain of large tumor antigen (From Topology)	H: N-terminal domain of large tumor antigen (From Topology)	T: N-terminal domain of large tumor antigen	F: UNK_F_TYPE	ECOD (1.6)
L	Polyoma_lg_T_C	e2v9pL1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Polyoma_lg_T_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
B	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
B	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
C	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
C	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
D	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
D	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
E	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
E	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
F	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
F	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
G	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
G	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
H	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
H	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
I	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
I	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
J	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
J	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
K	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
K	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
L	1.10.10.510	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Zinc finger, large T-antigen D1 domain	CATH (4.3.0)
L	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	REPLICATION PROTEIN E1	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ATP-dependent activity, acting on DNA catalytic activity, acting on DNA DNA translocase activity catalytic activity, acting on a nucleic acid chromatin extrusion motor activity catalytic activity ATP-dependent activity DNA binding nucleic acid binding ATP-dependent H3-H4 histone complex chaperone activity catalytic activity, acting on a protein histone chaperone activity ATP-dependent chromatin remodeler activity H3-H4 histone complex chaperone activity protein carrier chaperone ATP-dependent histone chaperone activity molecular carrier activity nucleic acid conformation isomerase activity isomerase activity DNA helicase activity single-stranded DNA helicase activity helicase activity 3'-5' DNA helicase activity single-stranded 3'-5' DNA helicase activity macromolecular conformation isomerase activity cohesin loader activity DNA clamp loader activity four-way junction helicase activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides ATP-dependent H2AZ histone chaperone activity forked DNA-dependent helicase activity double-stranded DNA helicase activity	nucleobase-containing compound metabolic process DNA replication metabolic process cellular process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process	host intracellular membrane-bounded organelle host cellular component host intracellular part cellular anatomical structure host cell part host intracellular region host cell nucleus host intracellular organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR046935	DNA helicase E1, DNA-binding domain superfamily, papillomavirus	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR046832	DNA helicase E1, DNA-binding domain, papillomavirus	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR001177	DNA helicase E1, C-terminal, Papillomavirus	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR014000	DNA helicase E1, N-terminal, Papillomavirus	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR037102	Zinc finger, large T-antigen D1 domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR016393	Replication protein E1, papillomavirus	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR014015	Helicase, superfamily 3, DNA virus	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

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.id_divider{ color: #ccc; padding: 0 10px 0 10px; } .extended_id_info{ color: #ccc; font-size: 18px; position: relative; top: -10px; left:-5px; } 2V9P | pdb_00002v9p

Crystal structure of papillomavirus E1 hexameric helicase DNA-free form

External Resource: Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage

2V9P | pdb_00002v9p