3IBY | pdb_00003iby

Structure of cytosolic domain of L. pneumophila FeoB

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d3ibyd_	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Legionella pneumophila ) [TaxId: 446 ],	SCOPe (2.08)
C	d3ibyc_	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Legionella pneumophila ) [TaxId: 446 ],	SCOPe (2.08)
B	d3ibyb_	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Legionella pneumophila ) [TaxId: 446 ],	SCOPe (2.08)
A	d3ibya_	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Legionella pneumophila ) [TaxId: 446 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	feoB_like	e3ibyD2	A: alpha complex topology	X: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	H: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	T: Cytosolic helical domain in ferrous iron transport protein B	F: feoB_like	ECOD (1.6)
D	MnmE_helical_2nd	e3ibyD3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MnmE_helical_2nd	ECOD (1.6)
C	feoB_like	e3ibyC2	A: alpha complex topology	X: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	H: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	T: Cytosolic helical domain in ferrous iron transport protein B	F: feoB_like	ECOD (1.6)
C	MnmE_helical_2nd	e3ibyC1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MnmE_helical_2nd	ECOD (1.6)
B	feoB_like	e3ibyB2	A: alpha complex topology	X: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	H: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	T: Cytosolic helical domain in ferrous iron transport protein B	F: feoB_like	ECOD (1.6)
B	MnmE_helical_2nd	e3ibyB1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MnmE_helical_2nd	ECOD (1.6)
A	feoB_like	e3ibyA2	A: alpha complex topology	X: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	H: Cytosolic helical domain in ferrous iron transport protein B (From Topology)	T: Cytosolic helical domain in ferrous iron transport protein B	F: feoB_like	ECOD (1.6)
A	MnmE_helical_2nd	e3ibyA3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MnmE_helical_2nd	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
D	1.10.287.1770	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
C	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
C	1.10.287.1770	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
B	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
B	1.10.287.1770	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
A	1.10.287.1770	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF01926	50S ribosome-binding GTPase (MMR_HSR1)	50S ribosome-binding GTPase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Ferrous iron transport protein B	monoatomic cation transmembrane transporter activity iron ion transmembrane transporter activity monoatomic ion transmembrane transporter activity ferrous iron transmembrane transporter activity transporter activity transition metal ion transmembrane transporter activity metal ion transmembrane transporter activity transmembrane transporter activity binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding monoatomic cation transmembrane transporter activity iron ion transmembrane transporter activity monoatomic ion transmembrane transporter activity ferrous iron transmembrane transporter activity transporter activity transition metal ion transmembrane transporter activity metal ion transmembrane transporter activity transmembrane transporter activity binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	-	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR050860	Fe(2+) Transporter FeoB GTPase	Family
A, B, C, D	IPR030389	FeoB-type guanine nucleotide-binding (G) domain	Domain
A, B, C, D	IPR003373	Ferrous iron transport protein B	Family
A, B, C, D	IPR011640	Ferrous iron transport protein B, C-terminal	Domain
A, B, C, D	IPR006073	GTP binding domain	Domain
A, B, C, D	IPR011642	Nucleoside transporter/FeoB GTPase, Gate domain	Domain
A, B, C, D	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.