3NWI | pdb_00003nwi

The Soluble Domain Structure of the ZntB Zn2+ Efflux System

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CorA_N	e3nwiA1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: CorA_N	ECOD (1.6)
B	CorA_N	e3nwiB1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: CorA_N	ECOD (1.6)
C	CorA_N	e3nwiC1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: CorA_N	ECOD (1.6)
D	CorA_N	e3nwiD1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: CorA_N	ECOD (1.6)
E	CorA_N	e3nwiE1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: CorA_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.460.20	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
A	1.20.58.340	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
B	3.30.460.20	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
B	1.20.58.340	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
C	3.30.460.20	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
C	1.20.58.340	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
D	3.30.460.20	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
D	1.20.58.340	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
E	3.30.460.20	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
E	1.20.58.340	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF01544	CorA-like Mg2+ transporter protein (CorA)	CorA-like Mg2+ transporter protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Zinc transport protein zntB	cation binding transition metal ion binding ion binding binding metal ion binding cobalt ion binding small molecule binding magnesium ion binding cobalt ion transmembrane transporter activity monoatomic cation transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity cation binding transition metal ion binding ion binding binding metal ion binding cobalt ion binding small molecule binding magnesium ion binding cobalt ion transmembrane transporter activity monoatomic cation transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transition metal ion transmembrane transporter activity metal ion transmembrane transporter activity transmembrane transporter activity zinc ion transmembrane transporter activity magnesium ion transmembrane transporter activity identical protein binding protein binding	-	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR002523	Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB	Family
A, B, C, D, E	IPR045861	CorA, cytoplasmic domain	Homologous Superfamily
A, B, C, D, E	IPR023714	Zinc transport protein ZntB	Family
A, B, C, D, E	IPR045863	CorA, transmembrane region	Homologous Superfamily

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	CorA Superfamily Ion Transporters	ZntB Zn⁺² transporter cytoplasmic domain, P2₁ space group

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.