3SDR | pdb_00003sdr

Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Terpene_synth_C	e3sdrA4	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: Terpene_synth_C	ECOD (1.6)
A	Terpene_synth	e3sdrA3	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: Terpene_synth	ECOD (1.6)
A	SQHop_cyclase_N	e3sdrA5	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: SQHop_cyclase_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.50.10.130	Mainly Alpha	Alpha/alpha barrel	Glycosyltransferase	Terpene synthase, N-terminal domain	CATH (4.3.0)
A	1.50.10.160	Mainly Alpha	Alpha/alpha barrel	Glycosyltransferase		CATH (4.3.0)
A	1.10.600.10	Mainly Alpha	Orthogonal Bundle	Farnesyl Diphosphate Synthase	Farnesyl Diphosphate Synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03936	Terpene synthase family, metal binding domain (Terpene_synth_C)	Terpene synthase family, metal binding domain	It has been suggested that this gene family be designated tps (for terpene synthase) [1]. It has been split into six subgroups on the basis of phylogeny, called tpsa-tpsf. tpsa includes vetispiridiene synthase Swiss:Q39979, 5-epi- aristolochene synt ...	It has been suggested that this gene family be designated tps (for terpene synthase) [1]. It has been split into six subgroups on the basis of phylogeny, called tpsa-tpsf. tpsa includes vetispiridiene synthase Swiss:Q39979, 5-epi- aristolochene synthase, Swiss:Q40577 and (+)-delta-cadinene synthase Swiss:P93665. tpsb includes (-)-limonene synthase, Swiss:Q40322. tpsc includes kaurene synthase A, Swiss:O04408. tpsd includes taxadiene synthase, Swiss:Q41594, pinene synthase, Swiss:O24475 and myrcene synthase, Swiss:O24474. tpse includes kaurene synthase B. tpsf includes linalool synthase.	Domain
A	PF01397	Terpene synthase, N-terminal domain (Terpene_synth)	Terpene synthase, N-terminal domain	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Alpha-bisabolene synthase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding carbon-oxygen lyase activity, acting on phosphates terpene synthase activity lyase activity catalytic activity carbon-oxygen lyase activity alpha-bisabolene synthase activity	diterpenoid metabolic process isoprenoid biosynthetic process lipid biosynthetic process primary metabolic process terpenoid biosynthetic process diterpenoid biosynthetic process biosynthetic process metabolic process cellular process terpenoid metabolic process isoprenoid metabolic process lipid metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR005630	Terpene synthase, metal-binding domain	Domain
A	IPR001906	Terpene synthase, N-terminal domain	Domain
A	IPR008949	Isoprenoid synthase domain superfamily	Homologous Superfamily
A	IPR036965	Terpene synthase, N-terminal domain superfamily	Homologous Superfamily
A	IPR044814	Terpene cyclases, class 1, plant	Family
A	IPR008930	Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid	Homologous Superfamily
A	IPR050148	Terpene synthase-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.