3TGW | pdb_00003tgw

Crystal structure of subunit B mutant H156A of the A1AO ATP synthase

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3tgwb3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)
B	d3tgwb1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)
B	d3tgwb2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)
A	d3tgwa3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)
A	d3tgwa1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)
A	d3tgwa2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	automated matches	automated matches	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	RecA-like P-loop NTPases	8056722	3002019	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8056717	3001034	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8056717	3001034	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	RecA-like P-loop NTPases	8056722	3002019	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	ATP-synt_ab_N	e3tgwB6	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
B	ATP-synt_ab_C	e3tgwB5	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
B	ATP-synt_ab	e3tgwB4	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
A	ATP-synt_ab_N	e3tgwA12	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
A	ATP-synt_ab_C	e3tgwA11	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
A	ATP-synt_ab	e3tgwA10	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.12240	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
A	3.40.50.12240	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	V-type ATP synthase beta chain	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process phosphate-containing compound metabolic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process nucleoside triphosphate biosynthetic process proton motive force-driven plasma membrane ATP synthesis primary metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process ribonucleoside triphosphate biosynthetic process purine-containing compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process	cell periphery cellular anatomical structure plasma membrane membrane protein-containing complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting two-sector ATPase complex membrane protein complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR020003	ATPase, alpha/beta subunit, nucleotide-binding domain, active site	Active Site
A, B	IPR000194	ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain	Domain
A, B	IPR055190	ATP synthase A/B type, C-terminal domain	Domain
A, B	IPR004100	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain	Domain
A, B	IPR005724	ATPase, A1 complex, beta subunit	Family
A, B	IPR022879	V-type ATP synthase regulatory subunit B/beta	Family
A, B	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.