Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyRecA-like P-loop NTPases 8018243 3002019 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056868 3000684 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018248 3001034 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056868 3000684 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018248 3001034 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyRecA-like P-loop NTPases 8018243 3002019 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyRecA-like P-loop NTPases 8018243 3002019 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018248 3001034 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056868 3000684 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyRecA-like P-loop NTPases 8018253 3002019 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018258 3001034 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056904 3000684 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056904 3000684 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018258 3001034 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyRecA-like P-loop NTPases 8018253 3002019 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyATP synthase alpha/beta N-terminal domain-like 8018258 3001034 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyATP synthase alpha/beta C-terminal domain-like 8056904 3000684 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyRecA-like P-loop NTPases 8018253 3002019 SCOP2B (2022-06-29)
H [auth I]SCOP2B SuperfamilyF1 ATPase inhibitor, IF1, C-terminal domain 8037355 3001557 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AATP-synt_ab_Ne4tsfA2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
AATP-synt_ab_Ce4tsfA3 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
AATP-synt_abe4tsfA1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
BATP-synt_ab_Ne4tsfB2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
BATP-synt_ab_Ce4tsfB1 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
BATP-synt_abe4tsfB3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
CATP-synt_ab_Ne4tsfC1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
CATP-synt_ab_Ce4tsfC2 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
CATP-synt_abe4tsfC3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
EATP-synt_ab_Ne4tsfE2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
EATP-synt_ab_Ce4tsfE1 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
EATP-synt_abe4tsfE3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
FATP-synt_ab_Ne4tsfF3 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
FATP-synt_ab_Ce4tsfF1 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
FATP-synt_abe4tsfF2 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
DATP-synt_ab_Ne4tsfD2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: ATP-synt_ab_NECOD (1.6)
DATP-synt_ab_Ce4tsfD1 A: alpha superhelicesX: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)T: C-terminal domain of alpha and beta subunits of F1 ATP synthaseF: ATP-synt_ab_CECOD (1.6)
DATP-synt_abe4tsfD3 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: ATP-synt_abECOD (1.6)
GATP-synte4tsfG1 A: a/b three-layered sandwichesX: ATP synthase (F1-ATPase), gamma subunit (From Topology)H: ATP synthase (F1-ATPase), gamma subunit (From Topology)T: ATP synthase (F1-ATPase), gamma subunitF: ATP-syntECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.40.30.20 Mainly Beta Beta Barrel Elongation Factor Tu (Ef-tu) domain 3CATH (4.3.0)
A3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
A1.20.150.20 Mainly Alpha Up-down Bundle Lysin ATP synthase alpha/beta chain, C-terminal domainCATH (4.3.0)
B2.40.30.20 Mainly Beta Beta Barrel Elongation Factor Tu (Ef-tu) domain 3CATH (4.3.0)
B3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
B1.20.150.20 Mainly Alpha Up-down Bundle Lysin ATP synthase alpha/beta chain, C-terminal domainCATH (4.3.0)
C2.40.30.20 Mainly Beta Beta Barrel Elongation Factor Tu (Ef-tu) domain 3CATH (4.3.0)
C3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
C1.20.150.20 Mainly Alpha Up-down Bundle Lysin ATP synthase alpha/beta chain, C-terminal domainCATH (4.3.0)
E2.40.10.170 Mainly Beta Beta Barrel Thrombin, subunit H CATH (4.3.0)
E3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
E1.10.1140.10 Mainly Alpha Orthogonal Bundle Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain Chain D, domain3CATH (4.3.0)
F2.40.10.170 Mainly Beta Beta Barrel Thrombin, subunit H CATH (4.3.0)
F3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
F1.10.1140.10 Mainly Alpha Orthogonal Bundle Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain Chain D, domain3CATH (4.3.0)
D2.40.10.170 Mainly Beta Beta Barrel Thrombin, subunit H CATH (4.3.0)
D3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
D1.10.1140.10 Mainly Alpha Orthogonal Bundle Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain Chain D, domain3CATH (4.3.0)
G1.10.287.80 Mainly Alpha Orthogonal Bundle Helix Hairpins ATP synthase, gamma subunit, helix hairpin domainCATH (4.3.0)
G3.40.1380.10 Alpha Beta 3-Layer(aba) Sandwich Pyruvate Kinase Chain: A, domain 1CATH (4.3.0)
H [auth I]1.20.5.500 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF00006ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)ATP synthase alpha/beta family, nucleotide-binding domainThis entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.Domain
A, B, C
PF00306ATP synthase alpha/beta chain, C terminal domain (ATP-synt_ab_C)ATP synthase alpha/beta chain, C terminal domain- Domain
A, B, C
PF02874ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)ATP synthase alpha/beta family, beta-barrel domainThis family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.Domain
D, E, F
PF00006ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)ATP synthase alpha/beta family, nucleotide-binding domainThis entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.Domain
D, E, F
PF22919C-terminal domain of V and A type ATP synthase (ATP-synt_VA_C)C-terminal domain of V and A type ATP synthaseThis entry represents a small alpha helical domain found at the C-terminus of a variety of ATP synthases.Domain
D, E, F
PF02874ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)ATP synthase alpha/beta family, beta-barrel domainThis family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.Domain
PF00231ATP synthase (ATP-synt)ATP synthase- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
ATP synthase subunit alpha, mitochondrial
D, E, F
ATP synthase subunit beta, mitochondrial
ATP synthase subunit gamma, mitochondrial
H [auth I],
I [auth H]
ATPase inhibitor, mitochondrial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C
IPR038376ATP synthase, alpha subunit, C-terminal domain superfamilyHomologous Superfamily
A, B, C
IPR004100ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomain
A, B, C
IPR033732ATP synthase, F1 complex, alpha subunit nucleotide-binding domainDomain
A, B, C
IPR036121ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamilyHomologous Superfamily
A, B, C
IPR023366ATP synthase subunit alpha, N-terminal domain-like superfamilyHomologous Superfamily
A, B, C
IPR000793ATP synthase, alpha subunit, C-terminalDomain
A, B, C
IPR020003ATPase, alpha/beta subunit, nucleotide-binding domain, active siteActive Site
A, B, C
IPR000194ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomain
A, B, C
IPR005294ATP synthase, F1 complex, alpha subunitFamily
A, B, C
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
D, E, F
IPR004100ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomain
D, E, F
IPR024034ATPase, F1/V1 complex, beta/alpha subunit, C-terminalHomologous Superfamily
D, E, F
IPR036121ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamilyHomologous Superfamily
D, E, F
IPR020003ATPase, alpha/beta subunit, nucleotide-binding domain, active siteActive Site
D, E, F
IPR050053ATPase alpha/beta chainsFamily
D, E, F
IPR000194ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomain
D, E, F
IPR055190ATP synthase A/B type, C-terminal domainDomain
D, E, F
IPR003593AAA+ ATPase domainDomain
D, E, F
IPR005722ATP synthase, F1 complex, beta subunitFamily
D, E, F
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR023632ATP synthase, F1 complex, gamma subunit conserved siteConserved Site
IPR000131ATP synthase, F1 complex, gamma subunitFamily
IPR035968ATP synthase, F1 complex, gamma subunit superfamilyHomologous Superfamily
H [auth I],
I [auth H]
IPR007648Mitochondrial ATPase inhibitorFamily