4GNW

Crystal structure of nitrophorin 4 triple mutant complex with ammonia

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4gnwa_	All beta proteins	Lipocalins	Lipocalins	Retinol binding protein-like	automated matches	Triatomid bug (Rhodnius prolixus ) [TaxId: 13249 ],	SCOPe (2.08)
B	d4gnwb_	All beta proteins	Lipocalins	Lipocalins	Retinol binding protein-like	automated matches	Triatomid bug (Rhodnius prolixus ) [TaxId: 13249 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Lipocalins	8043776	3001332	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Lipocalins	8043776	3001332	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Triabin	e4gnwA1	A: beta barrels	X: Lipocalins/Streptavidin	H: Lipocalins (From Topology)	T: Lipocalins	F: Triabin	ECOD (1.6)
B	Triabin	e4gnwB1	A: beta barrels	X: Lipocalins/Streptavidin	H: Lipocalins (From Topology)	T: Lipocalins	F: Triabin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.128.20	Mainly Beta	Beta Barrel	Lipocalin	Calycin beta-barrel core domain	CATH (4.3.0)
B	2.40.128.20	Mainly Beta	Beta Barrel	Lipocalin	Calycin beta-barrel core domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02087	Nitrophorin (Nitrophorin)	Nitrophorin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Nitrophorin-4	oxidoreductase activity catalytic activity nitric oxide binding binding small molecule binding cation binding histamine binding ion binding organic cyclic compound binding heterocyclic compound binding metal ion binding	regulation of tube diameter multicellular organismal process system process regulation of tube size biological regulation circulatory system process vascular process in circulatory system blood vessel diameter maintenance regulation of biological quality vasodilation blood circulation regulation of anatomical structure size	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012674	Calycin	Homologous Superfamily
A, B	IPR002351	Nitrophorin domain	Domain
A, B	IPR023613	Nitrophorin	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.