Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyN-terminal domain of argonaute 8053638 4004602 SCOP2 (2022-06-29)
ASCOP2 FamilyPAZ domain 8053639 4000853 SCOP2 (2022-06-29)
ASCOP2 FamilyMid domain of argonaute 8053640 4004605 SCOP2 (2022-06-29)
ASCOP2 FamilyPIWI domain 8053641 4002242 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyRNA-binding domain, RBD 8053643 3000110 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyPAZ domain 8053644 3001750 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyMid domain of argonaute 8053645 3002210 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyRibonuclease H-like 8053646 3000143 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APAZe5guhA2 A: beta barrelsX: SH3H: SH3T: SH3F: PAZECOD (1.6)
AArgoNe5guhA3 A: a+b two layersX: Alpha-beta plaitsH: Argonaute, N-terminal domain (From Topology)T: Argonaute, N-terminal domainF: ArgoNECOD (1.6)
AArgoL1e5guhA4 A: a+b two layersX: Alpha-beta plaitsH: Argonaute, N-terminal domain (From Topology)T: Argonaute, N-terminal domainF: ArgoL1ECOD (1.6)
APiwi_Ne5guhA1 A: a/b three-layered sandwichesX: Middle domain in Argonaute homologs (From Topology)H: Middle domain in Argonaute homologs (From Topology)T: Middle domain in Argonaute homologsF: Piwi_NECOD (1.6)
APiwi_Ce5guhA5 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Piwi_CECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF02171Piwi domain (Piwi)Piwi domain- Family
PF02170PAZ domain (PAZ)PAZ domainThis domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, that includes the Carpel ...Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
PIWI
RNA (28-MER)---

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR036397Ribonuclease H superfamilyHomologous Superfamily
IPR003100PAZ domainDomain
IPR036085PAZ domain superfamilyHomologous Superfamily
IPR003165Piwi domainDomain
IPR012337Ribonuclease H-like superfamilyHomologous Superfamily