5JQI | pdb_00005jqi

Crystal structure of FimH A62S from E. coli UTI89 bound to FimG N-terminal extension

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
F [auth D]	FimH_man-bind	e5jqiD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
F [auth D]	Fimbrial_1	e5jqiD2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
H [auth F]	FimH_man-bind	e5jqiF2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
H [auth F]	Fimbrial_1	e5jqiF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
D [auth B]	FimH_man-bind	e5jqiB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
D [auth B]	Fimbrial_1	e5jqiB2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
B [auth H]	FimH_man-bind	e5jqiH2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
B [auth H]	Fimbrial_1	e5jqiH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
F [auth D]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
H [auth F]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
D [auth B]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
B [auth H]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B [auth H], D [auth B], F [auth D], H [auth F]	Type 1 fimbiral adhesin FimH	-	cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms cell-substrate adhesion single-species biofilm formation aggregation of unicellular organisms submerged biofilm formation cell adhesion involved in single-species biofilm formation cell adhesion cellular process single-species submerged biofilm formation	pilus cell projection cellular anatomical structure
A [auth G], C [auth A], E [auth C], G [auth E]	FimG N-terminal extension	cation binding ion binding binding metal ion binding small molecule binding	cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms cell-substrate adhesion single-species biofilm formation aggregation of unicellular organisms submerged biofilm formation cell adhesion involved in single-species biofilm formation cell adhesion cellular process single-species submerged biofilm formation	pilus cell projection cellular anatomical structure

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth H], D [auth B], F [auth D], H [auth F]	IPR000259	Fimbrial-type adhesion domain	Domain
B [auth H], D [auth B], F [auth D], H [auth F]	IPR036937	Fimbrial-type adhesion domain superfamily	Homologous Superfamily
B [auth H], D [auth B], F [auth D], H [auth F]	IPR015243	FimH, mannose-binding domain	Domain
B [auth H], D [auth B], F [auth D], H [auth F]	IPR050263	Bacterial Fimbrial Adherence	Family
B [auth H], D [auth B], F [auth D], H [auth F]	IPR008966	Adhesion domain superfamily	Homologous Superfamily
A [auth G], C [auth A], E [auth C], G [auth E]	IPR036937	Fimbrial-type adhesion domain superfamily	Homologous Superfamily
A [auth G], C [auth A], E [auth C], G [auth E]	IPR050263	Bacterial Fimbrial Adherence	Family
A [auth G], C [auth A], E [auth C], G [auth E]	IPR008966	Adhesion domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.