6T63 | pdb_00006t63

A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH6

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
R [auth P]	Gag_p24_C	e6t63P2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
R [auth P]	Gag_p24_N	e6t63P1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
Q [auth N]	Gag_p24_C	e6t63N1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
Q [auth N]	Gag_p24_N	e6t63N2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
P [auth R]	Gag_p24_C	e6t63R1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
P [auth R]	Gag_p24_N	e6t63R2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
O [auth Q]	Gag_p24_C	e6t63Q1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
O [auth Q]	Gag_p24_N	e6t63Q2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
N [auth M]	Gag_p24_C	e6t63M2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
N [auth M]	Gag_p24_N	e6t63M1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
M [auth O]	Gag_p24_C	e6t63O2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
M [auth O]	Gag_p24_N	e6t63O1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
L	Gag_p24_C	e6t63L1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
L	Gag_p24_N	e6t63L2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
K	Gag_p24_C	e6t63K1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
K	Gag_p24_N	e6t63K2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
J	Gag_p24_C	e6t63J2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
J	Gag_p24_N	e6t63J1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
I [auth G]	Gag_p24_C	e6t63G2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
I [auth G]	Gag_p24_N	e6t63G1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
H [auth E]	Gag_p24_C	e6t63E1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
H [auth E]	Gag_p24_N	e6t63E2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
G [auth I]	Gag_p24_C	e6t63I1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
G [auth I]	Gag_p24_N	e6t63I2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
F [auth H]	Gag_p24_C	e6t63H1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
F [auth H]	Gag_p24_N	e6t63H2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
E [auth D]	Gag_p24_C	e6t63D1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
E [auth D]	Gag_p24_N	e6t63D2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
D [auth F]	Gag_p24_C	e6t63F1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
D [auth F]	Gag_p24_N	e6t63F2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
C	Gag_p24_C	e6t63C2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
C	Gag_p24_N	e6t63C1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
B	Gag_p24_C	e6t63B2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
B	Gag_p24_N	e6t63B1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
A	Gag_p24_C	e6t63A1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
A	Gag_p24_N	e6t63A2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	PF19317	Gag protein p24 C-terminal domain (Gag_p24_C)	Gag protein p24 C-terminal domain	p24 forms inner protein layer of the nucleocapsid. ELISA tests for p24 is the most commonly used method to demonstrate virus replication both in vivo and in vitro.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	Gag polyprotein	binding nucleic acid binding structural constituent of virion structural molecule activity cation binding transition metal ion binding zinc ion binding ion binding metal ion binding small molecule binding	virion assembly viral process viral budding viral budding via host ESCRT complex viral life cycle	viral nucleocapsid viral capsid virion component

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR045345	Retroviral nucleocapsid Gag protein p24, C-terminal domain	Domain
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR036875	Zinc finger, CCHC-type superfamily	Homologous Superfamily
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR014834	Gag protein p15	Domain
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR050195	Primate lentivirus group Gag polyprotein-like	Domain
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR001878	Zinc finger, CCHC-type	Domain
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR008919	Retrovirus capsid, N-terminal	Homologous Superfamily
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR010999	Retroviral matrix protein	Homologous Superfamily
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR012344	Matrix protein, lentiviral and alpha-retroviral, N-terminal	Homologous Superfamily
A, B, C, D [auth F], E [auth D], A, B, C, D [auth F], E [auth D], F [auth H], G [auth I], H [auth E], I [auth G], J, K, L, M [auth O], N [auth M], O [auth Q], P [auth R], Q [auth N], R [auth P]	IPR008916	Retrovirus capsid, C-terminal	Homologous Superfamily