6VLB | pdb_00006vlb

Crystal structure of ligand-free UDP-GlcNAc 2-epimerase from Neisseria meningitidis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d6vlbb_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Neisseria meningitidis Z2491 ) [TaxId: 122587 ],	SCOPe (2.08)
A	d6vlba_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Neisseria meningitidis Z2491 ) [TaxId: 122587 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2 Family	UDP-N-acetylglucosamine 2-epimerase	8101220	4000828	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Type B glycosyltransferase-like	8101221	3001586	SCOP2 (2022-06-29)
A	SCOP2B Superfamily	Type B glycosyltransferase-like	8101221	3001586	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Epimerase_2_C	e6vlbB2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_C	ECOD (1.6)
B	Epimerase_2_N	e6vlbB1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_N	ECOD (1.6)
A	Epimerase_2_C	e6vlbA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_C	ECOD (1.6)
A	Epimerase_2_N	e6vlbA1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Epimerase_2_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02350	UDP-N-acetylglucosamine 2-epimerase (Epimerase_2)	UDP-N-acetylglucosamine 2-epimerase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	UDP-N-acetylglucosamine 2-epimerase	isomerase activity racemase and epimerase activity UDP-N-acetylglucosamine 2-epimerase activity racemase and epimerase activity, acting on carbohydrates and derivatives catalytic activity	carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process primary metabolic process macromolecule biosynthetic process cellular component organization capsule organization polysaccharide metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process cellular component organization or biogenesis capsule polysaccharide biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process primary metabolic process macromolecule biosynthetic process cellular component organization capsule organization polysaccharide metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process cellular component organization or biogenesis capsule polysaccharide biosynthetic process external encapsulating structure organization	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR003331	UDP-N-acetylglucosamine 2-epimerase domain	Domain
A, B	IPR029767	UDP-N-acetylglucosamine 2-epimerase WecB-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.