Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors
External Resource: Annotation
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A [auth AAA] | Peptidase_M4_C | e7ajrAAA1 | A: mixed a+b and a/b | X: Zincin-like | H: Metalloproteases (zincins) catalytic domain (From Topology) | T: Metalloproteases (zincins) catalytic domain | F: Peptidase_M4_C | ECOD (1.6) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| A [auth AAA] | Keratinase KP2 |
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| A [auth AAA] | IPR001570 | Peptidase M4, C-terminal | Domain |
| A [auth AAA] | IPR013856 | Peptidase M4 domain | Domain |
| A [auth AAA] | IPR027268 | Peptidase M4/M1, CTD superfamily | Homologous Superfamily |
| A [auth AAA] | IPR050728 | Extracellular Zinc Metalloprotease M4 | Family |
| A [auth AAA] | IPR011096 | FTP domain | Domain |
| A [auth AAA] | IPR025711 | PepSY domain | Domain |
| A [auth AAA] | IPR023612 | Peptidase M4 | Family |
