7C5L
Crystal Structure of C150S mutant of Glyceraldehyde-3-phosphate-dehydrogenase1 from Escherichia coli at 2.1 Angstrom resolution
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B [auth P] | SCOP2B Superfamily | GAPDH-like | 8096384 | 3000043 | SCOP2B (2022-06-29) |
C [auth Q] | SCOP2B Superfamily | GAPDH-like | 8096384 | 3000043 | SCOP2B (2022-06-29) |
A [auth O] | SCOP2B Superfamily | GAPDH-like | 8096384 | 3000043 | SCOP2B (2022-06-29) |
D [auth R] | SCOP2B Superfamily | GAPDH-like | 8096384 | 3000043 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth P] | Gp_dh_C | e7c5lP1 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Gp_dh_C | ECOD (1.6) |
B [auth P] | Gp_dh_N_2 | e7c5lP2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Gp_dh_N_2 | ECOD (1.6) |
C [auth Q] | Gp_dh_C | e7c5lQ2 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Gp_dh_C | ECOD (1.6) |
C [auth Q] | Gp_dh_N_2 | e7c5lQ1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Gp_dh_N_2 | ECOD (1.6) |
A [auth O] | Gp_dh_C | e7c5lO1 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Gp_dh_C | ECOD (1.6) |
A [auth O] | Gp_dh_N_2 | e7c5lO2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Gp_dh_N_2 | ECOD (1.6) |
D [auth R] | Gp_dh_C | e7c5lR2 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Gp_dh_C | ECOD (1.6) |
D [auth R] | Gp_dh_N_2 | e7c5lR1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Gp_dh_N_2 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth O], B [auth P], C [auth Q], D [auth R] | PF02800 | Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain (Gp_dh_C) | Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain | GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. C-terminal domain is a mixed alpha/antiparallel beta fold. | Domain |
A [auth O], B [auth P], C [auth Q], D [auth R] | PF00044 | Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain (Gp_dh_N) | Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain | GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. N-terminal domain is a Rossmann NAD(P) binding fold. | Domain |