7EY2 | pdb_00007ey2

Bifunctional xylosidase/glucosidase LXYL D300N mutant with intermediate substrate xylose

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
F	Fn3-like	e7ey2F3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
F	Glyco_hydro_3	e7ey2F2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
F	Glyco_hydro_3_C	e7ey2F1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
E	Fn3-like	e7ey2E1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
E	Glyco_hydro_3	e7ey2E2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
E	Glyco_hydro_3_C	e7ey2E3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
D	Fn3-like	e7ey2D3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
D	Glyco_hydro_3	e7ey2D1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
D	Glyco_hydro_3_C	e7ey2D2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
C	Fn3-like	e7ey2C2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
C	Glyco_hydro_3	e7ey2C3	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
C	Glyco_hydro_3_C	e7ey2C1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
B	Fn3-like	e7ey2B1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
B	Glyco_hydro_3	e7ey2B2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
B	Glyco_hydro_3_C	e7ey2B3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)
A	Fn3-like	e7ey2A2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Fn3-like	ECOD (1.6)
A	Glyco_hydro_3	e7ey2A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_3	ECOD (1.6)
A	Glyco_hydro_3_C	e7ey2A3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Beta-D-glucan exohydrolase, C-terminal domain (From Topology)	T: Beta-D-glucan exohydrolase, C-terminal domain	F: Glyco_hydro_3_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
F	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (utative)
E	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (utative)
D	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (utative)
C	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (utative)
A	3.40.50.1700	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycoside hydrolase family 3 C-terminal domain	CATH (utative)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Beta-D-xylosidase/beta-D-glucosidase	hydrolase activity, acting on glycosyl bonds glucosidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity beta-glucosidase activity catalytic activity	carbohydrate metabolic process catabolic process glucan catabolic process carbohydrate catabolic process primary metabolic process macromolecule catabolic process polysaccharide metabolic process glucan metabolic process polysaccharide catabolic process metabolic process cellular process macromolecule metabolic process	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR050288	Cellulose-degrading glycosyl hydrolase 3	Family
A, B, C, D, E A, B, C, D, E, F	IPR001764	Glycoside hydrolase, family 3, N-terminal	Domain
A, B, C, D, E A, B, C, D, E, F	IPR036962	Glycoside hydrolase, family 3, N-terminal domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR026891	Fibronectin type III-like domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR036881	Glycoside hydrolase family 3 C-terminal domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR002772	Glycoside hydrolase family 3 C-terminal domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.