8QCI | pdb_00008qci

FCGBP D10 Assembly Segment

External Resource: Annotation


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B]PF08742C8 domain (C8)C8 domainThis domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often fo ...This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often found on proteins containing Pfam:PF00094 and Pfam:PF01826.
Domain
A [auth B]PF00094von Willebrand factor type D domain (VWD)von Willebrand factor type D domainSwiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods. This domain is structurally homologous to the C-terminal domain of repulsive guidance molecules (RGM) despite low sequence identity [2 ...Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods. This domain is structurally homologous to the C-terminal domain of repulsive guidance molecules (RGM) despite low sequence identity [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
B [auth A]IgGFc-binding protein- -
A [auth B]IgGFc-binding protein- -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
B [auth A]IPR035234IgGFc-binding protein, N-terminalDomain
B [auth A]IPR050780Mucin/von Willebrand/Thrombospondin superfamilyFamily
B [auth A]IPR025615TILa domainDomain
B [auth A]IPR003645Follistatin-like, N-terminalDomain
B [auth A]IPR002919Trypsin Inhibitor-like, cysteine rich domainDomain
B [auth A]IPR001007VWFC domainDomain
B [auth A]IPR001846von Willebrand factor, type D domainDomain
B [auth A]IPR014853VWF/SSPO/Zonadhesin-like, cysteine-rich domainDomain
B [auth A]IPR036084Serine protease inhibitor-like superfamilyHomologous Superfamily
B [auth A]IPR000742EGF-like domainDomain
A [auth B]IPR035234IgGFc-binding protein, N-terminalDomain
A [auth B]IPR050780Mucin/von Willebrand/Thrombospondin superfamilyFamily
A [auth B]IPR025615TILa domainDomain
A [auth B]IPR003645Follistatin-like, N-terminalDomain
A [auth B]IPR002919Trypsin Inhibitor-like, cysteine rich domainDomain
A [auth B]IPR001007VWFC domainDomain
A [auth B]IPR001846von Willebrand factor, type D domainDomain
A [auth B]IPR014853VWF/SSPO/Zonadhesin-like, cysteine-rich domainDomain
A [auth B]IPR036084Serine protease inhibitor-like superfamilyHomologous Superfamily
A [auth B]IPR000742EGF-like domainDomain

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
B [auth A]Pharos:  Q9Y6R7
A [auth B]Pharos:  Q9Y6R7