8TIE | pdb_00008tie

Double nuclear outer ring of Nup84-complexes from the yeast NPC

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
J [auth n]	SCOP2B Superfamily	Coat and nuclear envelope proteins	8054129	3002276	SCOP2B (2022-06-29)
C [auth c]	SCOP2B Superfamily	Coat and nuclear envelope proteins	8054129	3002276	SCOP2B (2022-06-29)
I [auth m]	SCOP2B Superfamily	Coat and nuclear envelope proteins	8054123	3002276	SCOP2B (2022-06-29)
B [auth b]	SCOP2B Superfamily	Coat and nuclear envelope proteins	8054123	3002276	SCOP2B (2022-06-29)
H [auth l]	SCOP2B Superfamily	Nucleoporin beta-propeller domain	8090978	3000456	SCOP2B (2022-06-29)
H [auth l]	SCOP2B Superfamily	Scaffolding nucleoporins	8090980	3002255	SCOP2B (2022-06-29)
A [auth a]	SCOP2B Superfamily	Scaffolding nucleoporins	8090980	3002255	SCOP2B (2022-06-29)
A [auth a]	SCOP2B Superfamily	Nucleoporin beta-propeller domain	8090978	3000456	SCOP2B (2022-06-29)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
G [auth g], N [auth r]	NUP133 isoform 1	structural molecule activity structural constituent of nuclear pore	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization organelle localization RNA transport nitrogen compound transport nucleocytoplasmic transport transport nuclear transport nucleic acid transport intracellular transport tRNA export from nucleus establishment of localization RNA export from nucleus tRNA transport establishment of RNA localization establishment of localization in cell RNA localization nuclear export nucleobase-containing compound transport chromosome organization transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery cellular response to stimulus cellular response to heat response to stimulus cellular response to stress response to stress response to heat response to abiotic stimulus response to temperature stimulus regulation of cellular process negative regulation of biological process cellular component biogenesis cellular component assembly chromatin organization negative regulation of cellular process chromatin remodeling negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process heterochromatin formation epigenetic regulation of gene expression negative regulation of metabolic process biological regulation heterochromatin organization regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression constitutive heterochromatin formation biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process silent mating-type cassette heterochromatin formation negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process establishment of protein localization protein localization to nucleus import into nucleus establishment of protein localization to organelle protein transport protein localization to organelle protein import into nucleus intracellular protein localization intracellular protein transport mRNA transport mRNA export from nucleus response to nitrogen compound mRNA export from nucleus in response to heat stress response to chemical poly(A)+ mRNA export from nucleus subtelomeric heterochromatin formation positive regulation of DNA-templated transcription positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process positive regulation of RNA biosynthetic process regulation of DNA-templated transcription double-strand break repair DNA metabolic process DNA damage response DNA repair post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery negative regulation of RNA biosynthetic process transcription by RNA polymerase II negative regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II negative regulation of RNA metabolic process positive regulation of transcription by RNA polymerase II	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane cytoplasm cytosol membraneless organelle intracellular membraneless organelle chromosome chromosome, telomeric region chromosomal region
F [auth f], M [auth q]	Nucleoporin NUP84	structural molecule activity structural constituent of nuclear pore identical protein binding protein binding binding	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization organelle localization subtelomeric heterochromatin formation regulation of cellular process negative regulation of biological process cellular component biogenesis cellular component assembly chromatin organization negative regulation of cellular process chromatin remodeling negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process heterochromatin formation epigenetic regulation of gene expression negative regulation of metabolic process biological regulation heterochromatin organization regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression constitutive heterochromatin formation biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process nitrogen compound transport nucleocytoplasmic transport transport nuclear transport mRNA transport mRNA export from nucleus establishment of localization in cell RNA localization nuclear export nucleobase-containing compound transport RNA transport nucleic acid transport intracellular transport establishment of localization RNA export from nucleus establishment of RNA localization positive regulation of DNA-templated transcription positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process positive regulation of RNA biosynthetic process regulation of DNA-templated transcription silent mating-type cassette heterochromatin formation cellular response to stimulus double-strand break repair response to stimulus DNA metabolic process cellular response to stress DNA damage response response to stress DNA repair chromosome organization transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery establishment of protein localization protein localization to nucleus import into nucleus establishment of protein localization to organelle protein transport protein localization to organelle protein import into nucleus intracellular protein localization intracellular protein transport transcription by RNA polymerase II regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to heat response to temperature stimulus cellular response to heat response to nitrogen compound mRNA export from nucleus in response to heat stress response to chemical response to abiotic stimulus	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane membraneless organelle intracellular membraneless organelle chromosome chromosome, telomeric region chromosomal region
E [auth e], L [auth p]	Nucleoporin Seh1	structural molecule activity structural constituent of nuclear pore	cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction positive regulation of TORC1 signaling intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction positive regulation of TOR signaling cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction positive regulation of TORC1 signaling intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction positive regulation of TOR signaling signal transduction regulation of TORC1 signaling positive regulation of cellular process TOR signaling regulation of biological process regulation of signaling regulation of TOR signaling biological regulation positive regulation of intracellular signal transduction regulation of response to stimulus regulation of cell communication cellular process TORC1 signaling positive regulation of signaling RNA transport nitrogen compound transport transport nucleic acid transport mRNA transport establishment of localization localization establishment of RNA localization macromolecule localization RNA localization nucleobase-containing compound transport establishment of protein localization protein transport intracellular protein localization cellular localization nucleocytoplasmic transport nuclear transport establishment of localization in cell intracellular transport response to nutrient levels cellular response to amino acid starvation cellular response to starvation cellular response to nutrient levels cellular response to stress response to stress response to amino acid starvation response to starvation	protein-containing complex Seh1-associated complex membrane-bounded organelle intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope protein-containing complex Seh1-associated complex membrane-bounded organelle intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane vacuolar membrane vacuole bounding membrane of organelle cytoplasm
D [auth d], K [auth o]	Protein transport protein SEC13	structural molecule activity	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis regulation of localization regulation of cellular process transport nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis regulation of localization regulation of cellular process transport positive regulation of biological process positive regulation of ER to Golgi vesicle-mediated transport vesicle-mediated transport establishment of localization in cell positive regulation of intracellular transport positive regulation of cellular process regulation of intracellular transport regulation of biological process regulation of ER to Golgi vesicle-mediated transport regulation of transport biological regulation intracellular transport endoplasmic reticulum to Golgi vesicle-mediated transport regulation of vesicle-mediated transport establishment of localization positive regulation of transport regulation of cellular localization Golgi vesicle transport protein exit from endoplasmic reticulum establishment of protein localization nitrogen compound transport protein transport intracellular protein localization intracellular protein transport membrane organization vesicle budding from membrane vesicle organization COPII-coated vesicle budding RNA transport nucleic acid transport mRNA transport establishment of RNA localization RNA localization nucleobase-containing compound transport cellular response to stimulus catabolic process response to stimulus proteolysis involved in protein catabolic process response to nitrogen compound proteasomal protein catabolic process primary metabolic process protein catabolic process macromolecule catabolic process ERAD pathway cellular response to stress response to chemical response to stress proteolysis metabolic process protein metabolic process macromolecule metabolic process response to endoplasmic reticulum stress positive regulation of cell communication positive regulation of signal transduction signaling regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction positive regulation of TOR signaling signal transduction TOR signaling regulation of signaling regulation of TOR signaling positive regulation of intracellular signal transduction regulation of response to stimulus regulation of cell communication positive regulation of signaling nucleocytoplasmic transport nuclear transport regulation of TORC1 signaling TORC1 signaling protein localization to nucleus import into nucleus establishment of protein localization to organelle protein localization to organelle protein import into nucleus regulation of protein exit from endoplasmic reticulum regulation of protein localization positive regulation of establishment of protein localization positive regulation of protein transport regulation of establishment of protein localization regulation of protein transport positive regulation of protein exit from endoplasmic reticulum positive regulation of protein localization regulation of intracellular protein transport positive regulation of intracellular protein transport positive regulation of TORC1 signaling positive regulation of DNA-templated transcription RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process regulation of gene expression biosynthetic process positive regulation of RNA biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore cell periphery vesicle coat intracellular vesicle transport vesicle membrane membrane protein complex membrane coat bounding membrane of organelle vesicle membrane cytoplasmic vesicle ER to Golgi transport vesicle membrane coated vesicle vesicle transport vesicle membrane coated membrane COPII vesicle coat cytoplasmic vesicle membrane coated vesicle membrane COPII-coated ER to Golgi transport vesicle cytoplasm organelle membrane organelle subcompartment endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum endoplasmic reticulum membrane Seh1-associated complex vacuolar membrane vacuole
C [auth c], J [auth n]	NUP145 isoform 1	hydrolase activity catalytic activity RNA binding binding nucleic acid binding nuclear localization sequence binding signal sequence binding peptide binding structural molecule activity structural constituent of nuclear pore	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization organelle localization RNA transport nitrogen compound transport nucleocytoplasmic transport transport nuclear transport nucleic acid transport intracellular transport tRNA export from nucleus establishment of localization RNA export from nucleus tRNA transport establishment of RNA localization establishment of localization in cell RNA localization nuclear export nucleobase-containing compound transport protein localization to nucleus protein localization to membrane protein localization to nuclear envelope protein localization to organelle intracellular protein localization protein localization to nuclear inner membrane regulation of localization regulation of biological process regulation of cellular process regulation of transport biological regulation regulation of nucleocytoplasmic transport regulation of cellular localization regulation of intracellular transport establishment of protein localization import into nucleus establishment of protein localization to organelle protein transport protein import into nucleus intracellular protein transport mRNA transport mRNA export from nucleus poly(A)+ mRNA export from nucleus gene expression macromolecule biosynthetic process biosynthetic process metabolic process macromolecule metabolic process NLS-bearing protein import into nucleus subtelomeric heterochromatin formation negative regulation of biological process cellular component biogenesis cellular component assembly chromatin organization negative regulation of cellular process chromatin remodeling negative regulation of macromolecule metabolic process regulation of biosynthetic process heterochromatin formation epigenetic regulation of gene expression negative regulation of metabolic process heterochromatin organization regulation of macromolecule metabolic process regulation of gene expression negative regulation of gene expression constitutive heterochromatin formation negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process regulation of metabolic process positive regulation of DNA-templated transcription positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process positive regulation of RNA biosynthetic process regulation of DNA-templated transcription cellular response to stimulus double-strand break repair response to stimulus DNA metabolic process cellular response to stress DNA damage response response to stress DNA repair chromosome organization transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane nuclear pore central transport channel membraneless organelle intracellular membraneless organelle chromosome chromosome, telomeric region chromosomal region nuclear pore cytoplasmic filaments
B [auth b], I [auth m]	Nucleoporin NUP85	structural molecule activity structural constituent of nuclear pore	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis nucleocytoplasmic transport transport nuclear transport nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis nucleocytoplasmic transport transport nuclear transport establishment of localization in cell intracellular transport establishment of localization establishment of organelle localization ribonucleoprotein complex biogenesis ribosomal subunit export from nucleus ribosomal large subunit export from nucleus cellular component biogenesis ribosome biogenesis organelle localization nuclear export ribosome localization establishment of protein localization nitrogen compound transport protein localization to nucleus import into nucleus establishment of protein localization to organelle protein transport protein localization to organelle protein import into nucleus intracellular protein localization intracellular protein transport mRNA transport mRNA export from nucleus RNA localization nucleobase-containing compound transport RNA transport nucleic acid transport gene expression macromolecule biosynthetic process RNA export from nucleus establishment of RNA localization biosynthetic process metabolic process macromolecule metabolic process regulation of cellular process positive regulation of DNA-templated transcription positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process regulation of gene expression positive regulation of RNA biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane
A [auth a], H [auth l]	Nucleoporin NUP120	structural molecule activity structural constituent of nuclear pore identical protein binding protein binding binding	nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization nuclear pore localization cellular localization localization within membrane protein-containing complex localization cellular component organization localization nucleus organization organelle organization macromolecule localization cellular process cellular component organization or biogenesis telomere localization telomere tethering at nuclear periphery chromosome localization organelle localization establishment of protein localization nitrogen compound transport nucleocytoplasmic transport transport nuclear transport intracellular transport protein export from nucleus establishment of localization protein transport establishment of localization in cell intracellular protein localization nuclear export intracellular protein transport subtelomeric heterochromatin formation regulation of cellular process negative regulation of biological process cellular component biogenesis cellular component assembly chromatin organization negative regulation of cellular process chromatin remodeling negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process heterochromatin formation epigenetic regulation of gene expression negative regulation of metabolic process biological regulation heterochromatin organization regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression constitutive heterochromatin formation biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process mRNA transport mRNA export from nucleus RNA localization nucleobase-containing compound transport RNA transport nucleic acid transport RNA export from nucleus establishment of RNA localization positive regulation of DNA-templated transcription positive regulation of biological process RNA metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process positive regulation of RNA biosynthetic process regulation of DNA-templated transcription cellular response to stimulus double-strand break repair response to stimulus DNA metabolic process cellular response to stress DNA damage response response to stress DNA repair chromosome organization transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery negative regulation of RNA biosynthetic process transcription by RNA polymerase II negative regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II negative regulation of RNA metabolic process establishment of organelle localization ribonucleoprotein complex biogenesis ribosomal subunit export from nucleus ribosomal large subunit export from nucleus ribosome biogenesis ribosome localization protein localization to nucleus import into nucleus establishment of protein localization to organelle protein localization to organelle protein import into nucleus positive regulation of transcription by RNA polymerase II response to heat response to temperature stimulus cellular response to heat response to nitrogen compound mRNA export from nucleus in response to heat stress response to chemical response to abiotic stimulus	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex nuclear pore outer ring intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle envelope cellular anatomical structure organelle nuclear envelope nuclear pore nuclear membrane membrane organelle membrane membraneless organelle intracellular membraneless organelle chromosome chromosome, telomeric region chromosomal region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
G [auth g], N [auth r]	IPR037624	Nuclear pore complex protein Nup133-like	Family
G [auth g], N [auth r]	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
G [auth g], N [auth r]	IPR014908	Nucleoporin, Nup133/Nup155-like, N-terminal	Domain
F [auth f], M [auth q]	IPR007252	Nuclear pore protein 84/107	Family
E [auth e], L [auth p]	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
E [auth e], L [auth p]	IPR037363	Sec13/Seh1 family	Family
E [auth e], L [auth p]	IPR001680	WD40 repeat	Repeat
E [auth e], L [auth p]	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
D [auth d], K [auth o]	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
D [auth d], K [auth o]	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
D [auth d], K [auth o]	IPR037363	Sec13/Seh1 family	Family
D [auth d], K [auth o]	IPR001680	WD40 repeat	Repeat
C [auth c], J [auth n]	IPR025574	Nucleoporin FG repeat	Repeat
C [auth c], J [auth n]	IPR037665	Nucleoporin peptidase S59-like	Family
C [auth c], J [auth n]	IPR036903	Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain superfamily	Homologous Superfamily
C [auth c], J [auth n]	IPR007230	Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain	Domain
C [auth c], J [auth n]	IPR021967	Nuclear pore complex protein NUP96, C-terminal domain	Domain
B [auth b], I [auth m]	IPR011502	Nucleoporin Nup85-like	Family
A [auth a], H [auth l]	IPR021717	Nucleoporin Nup120/160	Family
A [auth a], H [auth l]	IPR055090	Nucleoporin NUP120, helical domain, saccharomycetes	Domain