9G8K | pdb_00009g8k

Structure of K+-dependent Na+-PPase from Thermotoga maritima in complex with Ca2+ and Etidronate

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Membrane-integral pyrophosphatase-like	8092367	3002599	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Membrane-integral pyrophosphatase-like	8092367	3002599	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03030	Inorganic H+ pyrophosphatase (H_PPase)	Inorganic H+ pyrophosphatase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	K(+)-stimulated pyrophosphate-energized sodium pump	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding calcium ion binding potassium ion binding alkali metal ion binding monoatomic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity sodium ion transmembrane transporter activity metal ion transmembrane transporter activity cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding calcium ion binding potassium ion binding alkali metal ion binding monoatomic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity sodium ion transmembrane transporter activity metal ion transmembrane transporter activity transmembrane transporter activity pyrophosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity inorganic diphosphate phosphatase activity hydrolase activity, acting on acid anhydrides catalytic activity identical protein binding protein binding protein homodimerization activity protein dimerization activity active monoatomic ion transmembrane transporter activity proton transmembrane transporter activity active transmembrane transporter activity primary active transmembrane transporter activity diphosphate hydrolysis-driven proton transmembrane transporter activity	transport monoatomic ion transmembrane transport sodium ion transmembrane transport establishment of localization metal ion transport monoatomic cation transmembrane transport transmembrane transport localization monoatomic ion transport cellular process monoatomic cation transport sodium ion transport	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR004131	Pyrophosphate-energised proton pump	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.