9H74 | pdb_00009h74

Late-stage 48S Initiation Complex with eIF3 (LS48S-eIF3 IC) guided by the trans-RNA

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
I [auth F]	Ribosomal protein S3	DNA binding binding nucleic acid binding DNA-(apurinic or apyrimidinic site) endonuclease activity endonuclease activity catalytic activity, acting on a nucleic acid DNA nuclease activity DNA endonuclease activity catalytic activity, acting on DNA nuclease activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity lyase activity catalytic activity carbon-oxygen lyase activity DNA binding binding nucleic acid binding DNA-(apurinic or apyrimidinic site) endonuclease activity endonuclease activity catalytic activity, acting on a nucleic acid DNA nuclease activity DNA endonuclease activity catalytic activity, acting on DNA nuclease activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity lyase activity catalytic activity carbon-oxygen lyase activity RNA binding structural molecule activity structural constituent of ribosome	cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction regulation of programmed cell death positive regulation of apoptotic signaling pathway cell communication positive regulation of response to stimulus signal transduction positive regulation of cellular process cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction regulation of programmed cell death positive regulation of apoptotic signaling pathway cell communication positive regulation of response to stimulus signal transduction positive regulation of cellular process regulation of biological process regulation of signaling positive regulation of programmed cell death regulation of apoptotic process biological regulation cell death positive regulation of apoptotic process apoptotic signaling pathway regulation of response to stimulus regulation of cell communication cellular process apoptotic process programmed cell death positive regulation of signaling regulation of apoptotic signaling pathway primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular response to stress DNA damage response response to stress metabolic process macromolecule metabolic process DNA repair cell division regulation of biosynthetic process regulation of protein metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process protein biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression regulation of gene expression biosynthetic process regulation of translation regulation of macromolecule biosynthetic process protein metabolic process regulation of metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane nucleus membrane-enclosed lumen intracellular membraneless organelle nucleolus intracellular organelle lumen organelle lumen membraneless organelle nuclear lumen cytosolic ribosome ribosome cytosol cytoskeleton spindle microtubule cytoskeleton cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
H [auth E]	Small ribosomal subunit protein uS5	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol
G [auth D]	40S ribosomal protein S3a	structural molecule activity structural constituent of ribosome	developmental process cellular developmental process cell differentiation cellular process biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
F [auth C]	40S ribosomal protein SA	protein binding binding virus receptor activity exogenous protein binding structural molecule activity structural constituent of ribosome extracellular matrix binding laminin binding cell adhesion molecule binding laminin receptor activity cell adhesion mediator activity	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cell periphery cellular anatomical structure plasma membrane membrane cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex cell periphery cellular anatomical structure plasma membrane membrane cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol membrane-bounded organelle nucleus intracellular membrane-bounded organelle
YA [auth y]	Eukaryotic translation initiation factor 3 subunit A	translation factor activity translation initiation factor activity RNA binding binding nucleic acid binding mRNA binding	primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process translation reinitiation cytoplasmic translation cytoplasmic translational initiation metabolic process cellular process translational initiation protein metabolic process macromolecule metabolic process primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process translation reinitiation cytoplasmic translation cytoplasmic translational initiation metabolic process cellular process translational initiation protein metabolic process macromolecule metabolic process viral gene expression viral process viral translation IRES-dependent viral translational initiation viral translational termination-reinitiation ribonucleoprotein complex biogenesis protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization formation of cytoplasmic translation initiation complex	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm multi-eIF complex cytosol postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse cell junction asymmetric synapse eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3e nucleoplasm eukaryotic translation initiation factor 3 complex, eIF3m
XA [auth w]	Eukaryotic translation initiation factor 3 subunit E	translation factor activity translation initiation factor activity	regulation of cellular process positive regulation of protein metabolic process positive regulation of biological process positive regulation of translation protein biosynthetic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression positive regulation of metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process protein metabolic process positive regulation of cellular process regulation of biosynthetic process regulation of cellular process positive regulation of protein metabolic process positive regulation of biological process positive regulation of translation protein biosynthetic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression positive regulation of metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process protein metabolic process positive regulation of cellular process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression biosynthetic process positive regulation of gene expression regulation of translation regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process catabolic process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay negative regulation of biological process RNA metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process mRNA catabolic process nuclear-transcribed mRNA catabolic process negative regulation of metabolic process mRNA metabolic process nucleic acid metabolic process nucleobase-containing compound catabolic process negative regulation of gene expression negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process ribonucleoprotein complex biogenesis protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein-containing complex organization formation of cytoplasmic translation initiation complex cytoplasmic translation cytoplasmic translational initiation	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm cytosol postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization organelle synapse protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm cytosol postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization organelle synapse cell junction asymmetric synapse eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3e membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle intracellular organelle lumen nuclear body intracellular organelle nucleoplasm organelle lumen membraneless organelle PML body nuclear lumen
E [auth B]	protein-synthesizing GTPase	translation factor activity translation initiation factor activity RNA binding binding tRNA binding nucleic acid binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding translation factor activity translation initiation factor activity RNA binding binding tRNA binding nucleic acid binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process formation of translation preinitiation complex protein-containing complex organization primary metabolic process ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process formation of translation preinitiation complex protein-containing complex organization primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex eukaryotic translation initiation factor 2 complex
WA [auth v]	Eukaryotic translation initiation factor 3 subunit C	translation factor activity translation initiation factor activity protein binding binding translation initiation factor binding RNA binding nucleic acid binding	ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m
VA [auth u]	Eukaryotic translation initiation factor 3 subunit M	translation factor activity translation initiation factor activity	ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m
UA [auth t]	Eukaryotic translation initiation factor 3 subunit L	translation factor activity translation initiation factor activity	viral gene expression viral process viral translational termination-reinitiation viral translation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis viral gene expression viral process viral translational termination-reinitiation viral translation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen fibrillar center organelle membraneless organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen fibrillar center organelle membraneless organelle nuclear lumen protein-containing complex eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic 48S preinitiation complex nucleoplasm eukaryotic translation initiation factor 3 complex synapse cell junction
TA [auth s]	Eukaryotic translation initiation factor 3 subunit K	translation factor activity translation initiation factor activity ribonucleoprotein complex binding protein-containing complex binding binding ribosome binding RNA binding nucleic acid binding	regulation of cellular process protein biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression translational initiation protein metabolic process regulation of biosynthetic process regulation of biological process regulation of translational initiation regulation of protein metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression regulation of cellular process protein biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression translational initiation protein metabolic process regulation of biosynthetic process regulation of biological process regulation of translational initiation regulation of protein metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression biosynthetic process regulation of translation regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process ribonucleoprotein complex biogenesis protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization formation of cytoplasmic translation initiation complex cytoplasmic translation cytoplasmic translational initiation	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic translation initiation factor 3 complex eukaryotic 48S preinitiation complex membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle
SA [auth r]	Eukaryotic translation initiation factor 3 subunit H	translation factor activity translation initiation factor activity ubiquitin-like protein peptidase activity peptidase activity catalytic activity, acting on a protein metal-dependent deubiquitinase activity hydrolase activity metallopeptidase activity catalytic activity deubiquitinase activity	ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex
RA [auth q]	Eukaryotic translation initiation factor 3 subunit F	translation factor activity translation initiation factor activity cysteine-type peptidase activity ubiquitin-like protein peptidase activity peptidase activity cysteine-type deubiquitinase activity catalytic activity, acting on a protein hydrolase activity catalytic activity deubiquitinase activity protein binding binding translation initiation factor binding identical protein binding translation factor activity translation initiation factor activity cysteine-type peptidase activity ubiquitin-like protein peptidase activity peptidase activity cysteine-type deubiquitinase activity catalytic activity, acting on a protein hydrolase activity catalytic activity deubiquitinase activity protein binding binding translation initiation factor binding identical protein binding metal-dependent deubiquitinase activity metallopeptidase activity	viral gene expression viral process viral translation IRES-dependent viral translational initiation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis viral gene expression viral process viral translation IRES-dependent viral translational initiation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm synapse cell junction eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m
QA [auth o]	Eukaryotic translation initiation factor 5	translation factor activity translation initiation factor activity protein binding binding eukaryotic initiation factor eIF2 binding translation initiation factor binding GTPase regulator activity enzyme regulator activity GDP-dissociation inhibitor activity nucleoside-triphosphatase regulator activity molecular function regulator activity enzyme activator activity GTPase activator activity molecular function activator activity translation factor activity translation initiation factor activity protein binding binding eukaryotic initiation factor eIF2 binding translation initiation factor binding GTPase regulator activity enzyme regulator activity GDP-dissociation inhibitor activity nucleoside-triphosphatase regulator activity molecular function regulator activity enzyme activator activity GTPase activator activity molecular function activator activity guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol
PA [auth n]	40S ribosomal protein S25	structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process cellular component organization or biogenesis RNA processing rRNA metabolic process ribosomal small subunit biogenesis	postsynaptic density postsynapse cellular anatomical structure neuron to neuron synapse postsynaptic specialization organelle synapse cell junction asymmetric synapse membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle postsynaptic density postsynapse cellular anatomical structure neuron to neuron synapse postsynaptic specialization organelle synapse cell junction asymmetric synapse membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
OA [auth m]	Eukaryotic translation initiation factor 3 subunit D	translation factor activity translation initiation factor activity RNA binding mRNA cap binding binding nucleic acid binding RNA cap binding mRNA binding	viral gene expression viral process viral translational termination-reinitiation viral translation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis viral gene expression viral process viral translational termination-reinitiation viral translation ribonucleoprotein complex biogenesis protein biosynthetic process protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly translational initiation cellular component organization or biogenesis protein metabolic process protein-containing complex organization formation of cytoplasmic translation initiation complex primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process cytoplasmic translational initiation metabolic process macromolecule metabolic process IRES-dependent viral translational initiation cap-dependent translational initiation	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m synapse cell junction
NA [auth l]	60S ribosomal protein L41	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome
D [auth A]	Eukaryotic translation initiation factor 2 subunit 1	translation factor activity translation initiation factor activity ribonucleoprotein complex binding protein-containing complex binding binding ribosome binding RNA binding nucleic acid binding	cellular response to stimulus cellular response to chemical stimulus cellular response to stress response to stimulus response to stress response to chemical cellular process cellular response to chemical stress response to endoplasmic reticulum stress	intracellular anatomical structure cytoplasmic ribonucleoprotein granule intracellular membraneless organelle ribonucleoprotein granule intracellular organelle cellular anatomical structure organelle membraneless organelle cytoplasm supramolecular complex cytoplasmic stress granule protein-containing complex eukaryotic translation initiation factor 2 complex ribonucleoprotein complex intracellular anatomical structure cytoplasmic ribonucleoprotein granule intracellular membraneless organelle ribonucleoprotein granule intracellular organelle cellular anatomical structure organelle membraneless organelle cytoplasm supramolecular complex cytoplasmic stress granule protein-containing complex eukaryotic translation initiation factor 2 complex ribonucleoprotein complex eukaryotic 48S preinitiation complex cytosolic translation preinitiation complex
MA [auth k]	ATP binding cassette subfamily E member 1	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity	regulation of biological process regulation of cellular process biological regulation metabolic process cellular process regulation of macromolecule metabolic process macromolecule metabolic process regulation of metabolic process biosynthetic process primary metabolic process protein metabolic process translation gene expression protein biosynthetic process regulation of biological process regulation of cellular process biological regulation metabolic process cellular process regulation of macromolecule metabolic process macromolecule metabolic process regulation of metabolic process biosynthetic process primary metabolic process protein metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm
LA [auth j]	Eukaryotic translation initiation factor 1A, X-chromosomal	translation factor activity translation initiation factor activity RNA binding binding nucleic acid binding translation factor activity, RNA binding tRNA binding	primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process translational initiation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis organelle assembly membraneless organelle assembly primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process translational initiation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis organelle assembly membraneless organelle assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization cellular component assembly cellular component organization or biogenesis ribosome assembly	protein-containing complex cellular anatomical structure intracellular anatomical structure eukaryotic 43S preinitiation complex ribonucleoprotein complex cytosolic translation preinitiation complex cytoplasm multi-eIF complex synapse cell junction cytosol eukaryotic 48S preinitiation complex
KA [auth i]	40S ribosomal protein S30	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol membrane-bounded organelle nucleus intracellular membrane-bounded organelle
JA [auth g]	Small ribosomal subunit protein RACK1	translation regulator activity ribonucleoprotein complex binding protein-containing complex binding binding ribosome binding	rhythmic process developmental process multicellular organism development multicellular organismal process anatomical structure morphogenesis embryonic morphogenesis anatomical structure development embryo development gastrulation cellular process apoptotic process cell death programmed cell death	somatodendritic compartment cell body cellular anatomical structure perikaryon neuronal cell body intracellular anatomical structure perinuclear region of cytoplasm cytoplasm cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection phagocytic cup somatodendritic compartment cell body cellular anatomical structure perikaryon neuronal cell body intracellular anatomical structure perinuclear region of cytoplasm cytoplasm cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection phagocytic cup cell periphery plasma membrane membrane protein-containing complex ribonucleoprotein complex intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome membrane-bounded organelle nucleus intracellular membrane-bounded organelle
IA [auth f]	Ribosomal protein S27a	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex ribonucleoprotein complex
HA [auth e]	40S ribosomal protein S29	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome	primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol rough endoplasmic reticulum membrane-bounded organelle endoplasmic reticulum intracellular membrane-bounded organelle endomembrane system
GA [auth d]	40S ribosomal protein S28	structural molecule activity structural constituent of ribosome	primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis ribosome assembly RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process maturation of SSU-rRNA RNA processing rRNA metabolic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex preribosome nuclear protein-containing complex small-subunit processome ribonucleoprotein complex synapse cell junction cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit rough endoplasmic reticulum endoplasmic reticulum endomembrane system
FA [auth c]	40S ribosomal protein S27	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome	cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process metabolic process macromolecule metabolic process RNA processing rRNA metabolic process protein metabolic process translation protein biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex preribosome nuclear protein-containing complex small-subunit processome ribonucleoprotein complex postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse cell junction asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
EA [auth b]	40S ribosomal protein S26	RNA binding binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol rough endoplasmic reticulum membrane-bounded organelle endoplasmic reticulum intracellular membrane-bounded organelle endomembrane system
DA [auth a]	40S ribosomal protein S24	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol
C [auth 3]	Linear mRNA	-	-	-
CA [auth Z]	40S ribosomal protein S23	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome cytosolic ribosome cytoplasm cytosol rough endoplasmic reticulum endoplasmic reticulum endomembrane system
BA [auth Y]	Ribosomal protein S15a	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex ribonucleoprotein complex
AA [auth X]	40S ribosomal protein S21	structural molecule activity structural constituent of ribosome	primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing primary metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA RNA 3'-end processing cellular component organization or biogenesis RNA processing rRNA metabolic process endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleobase-containing compound biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA 3'-end processing endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosolic small ribosomal subunit protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle intracellular organelle ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol rough endoplasmic reticulum membrane-bounded organelle endoplasmic reticulum intracellular membrane-bounded organelle endomembrane system synapse cell junction
Z [auth W]	40S ribosomal protein uS10	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure ribonucleoprotein complex organelle membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol
Y [auth V]	40S ribosomal protein eS19	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
X [auth U]	40S ribosomal protein uS13	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure ribonucleoprotein complex organelle membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol
W [auth T]	40S ribosomal protein eS17	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex ribonucleoprotein complex
V [auth S]	Ribosomal protein S16	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process biosynthetic process cellular process metabolic process macromolecule metabolic process protein metabolic process translation protein biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
U [auth R]	40S ribosomal protein uS19	enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity molecular function regulator activity enzyme inhibitor activity protein binding binding MDM2/MDM4 family protein binding RNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator signal transduction positive regulation of cellular process regulation of biological process regulation of signaling biological regulation positive regulation of intracellular signal transduction signal transduction by p53 class mediator regulation of response to stimulus regulation of cell communication cellular process positive regulation of signaling establishment of organelle localization cellular localization ribonucleoprotein complex biogenesis nucleocytoplasmic transport transport nuclear transport ribosomal subunit export from nucleus intracellular transport establishment of localization cellular component biogenesis localization ribosome biogenesis ribosomal small subunit export from nucleus organelle localization establishment of localization in cell cellular component organization or biogenesis nuclear export ribosome localization RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process metabolic process macromolecule metabolic process RNA processing rRNA metabolic process organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly protein metabolic process translation protein biosynthetic process	intracellular organelle cellular anatomical structure intracellular anatomical structure cytosolic ribosome organelle membraneless organelle intracellular membraneless organelle ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit intracellular organelle cellular anatomical structure intracellular anatomical structure cytosolic ribosome organelle membraneless organelle intracellular membraneless organelle ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
T [auth Q]	40S ribosomal protein uS11	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome cytoplasm
B [auth 2]	18S ribosomal RNA	-	-	-
S [auth P]	40S ribosomal protein S13	RNA binding small ribosomal subunit rRNA binding binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
R [auth O]	40S ribosomal protein S12	structural molecule activity structural constituent of ribosome	cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling regulation of canonical Wnt signaling pathway canonical Wnt signaling pathway cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling regulation of canonical Wnt signaling pathway canonical Wnt signaling pathway positive regulation of biological process regulation of signal transduction cell communication positive regulation of response to stimulus positive regulation of Wnt signaling pathway signal transduction Wnt signaling pathway positive regulation of cellular process positive regulation of canonical Wnt signaling pathway regulation of biological process regulation of signaling cell surface receptor signaling pathway regulation of Wnt signaling pathway biological regulation regulation of response to stimulus regulation of cell communication positive regulation of signaling biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol Golgi apparatus endomembrane system protein-containing complex preribosome nuclear protein-containing complex small-subunit processome ribonucleoprotein complex cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
Q [auth N]	40S ribosomal protein S11	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
P [auth M]	Small ribosomal subunit protein eS10	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	-	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit cytosolic ribosome ribonucleoprotein complex ribosome cytoplasm cytosol
O [auth L]	40S ribosomal protein S9	RNA binding binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis ribosomal small subunit biogenesis biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
N [auth K]	Small ribosomal subunit protein eS8	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex ribonucleoprotein complex
M [auth J]	40S ribosomal protein S7	structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process cellular component organization or biogenesis RNA processing rRNA metabolic process ribosomal small subunit biogenesis protein metabolic process translation protein biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen 90S preribosome preribosome protein-containing complex ribonucleoprotein complex cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit cytosolic ribosome ribosome cytoplasm cytosol nuclear protein-containing complex small-subunit processome centrosome microtubule organizing center cytoskeleton microtubule cytoskeleton
L [auth I]	Small ribosomal subunit protein eS6	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol protein-containing complex ribonucleoprotein complex
K [auth H]	Ribosomal protein S5	RNA binding binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome cytosolic ribosome cytoplasm cytosol
J [auth G]	40S ribosomal protein S4	RNA binding binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression protein biosynthetic process macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
A [auth 1]	Initiator methionylated tRNA	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
I [auth F]	IPR005703	Small ribosomal subunit protein uS3, eukaryota/archaeal	Family
I [auth F]	IPR001351	Small ribosomal subunit protein uS3, C-terminal	Domain
I [auth F]	IPR009019	K homology domain superfamily, prokaryotic type	Homologous Superfamily
I [auth F]	IPR004044	K Homology domain, type 2	Domain
I [auth F]	IPR015946	K homology domain-like, alpha/beta	Homologous Superfamily
I [auth F]	IPR036419	Ribosomal protein S3, C-terminal domain superfamily	Homologous Superfamily
I [auth F]	IPR018280	Small ribosomal subunit protein uS3, conserved site	Conserved Site
H [auth E]	IPR005711	Small ribosomal subunit protein uS5, eukaryota_archaea	Family
H [auth E]	IPR000851	Small ribosomal subunit protein uS5	Family
H [auth E]	IPR005324	Small ribosomal subunit protein uS5, C-terminal	Domain
H [auth E]	IPR013810	Small ribosomal subunit protein uS5, N-terminal	Domain
H [auth E]	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
H [auth E]	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
G [auth D]	IPR001593	Small ribosomal subunit protein eS1	Family
G [auth D]	IPR018281	Small ribosomal subunit protein eS1, conserved site	Conserved Site
G [auth D]	IPR027500	Small ribosomal subunit protein eS1, eukaryota	Family
F [auth C]	IPR032281	Small ribosomal subunit protein uS2, C-terminal domain	Domain
F [auth C]	IPR027498	Small ribosomal subunit protein uS2, eukaryota	Family
F [auth C]	IPR027504	Small ribosomal subunit protein uS2, vertebrates	Family
F [auth C]	IPR023591	Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily	Homologous Superfamily
F [auth C]	IPR018130	Small ribosomal subunit protein uS2, conserved site	Conserved Site
F [auth C]	IPR001865	Small ribosomal subunit protein uS2	Family
F [auth C]	IPR005707	Small ribosomal subunit protein uS2, eukaryota/archaea	Family
YA [auth y]	IPR027512	Eukaryotic translation initiation factor 3 subunit A	Family
YA [auth y]	IPR000717	Proteasome component (PCI) domain	Domain
YA [auth y]	IPR054711	eIF3a, PCI domain, TPR-like region	Domain
XA [auth w]	IPR016650	Eukaryotic translation initiation factor 3 subunit E	Family
XA [auth w]	IPR019010	Eukaryotic translation initiation factor 3 subunit E, N-terminal	Domain
XA [auth w]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
XA [auth w]	IPR000717	Proteasome component (PCI) domain	Domain
E [auth B]	IPR000795	Translational (tr)-type GTP-binding domain	Domain
E [auth B]	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal	Homologous Superfamily
E [auth B]	IPR004161	Translation elongation factor EFTu-like, domain 2	Domain
E [auth B]	IPR050543	Eukaryotic Initiation Factor 2 Gamma Subunit	Family
E [auth B]	IPR044128	Initiation factor eIF2 gamma, GTP-binding domain	Domain
E [auth B]	IPR015256	Initiation factor eIF2 gamma, C-terminal	Domain
E [auth B]	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
E [auth B]	IPR044127	Initiation factor eIF2 gamma, domain 2	Domain
E [auth B]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
WA [auth v]	IPR027516	Eukaryotic translation initiation factor 3 subunit C	Family
WA [auth v]	IPR000717	Proteasome component (PCI) domain	Domain
WA [auth v]	IPR008905	Eukaryotic translation initiation factor 3 subunit C, N-terminal domain	Domain
WA [auth v]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
WA [auth v]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
VA [auth u]	IPR045237	Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7	Family
VA [auth u]	IPR000717	Proteasome component (PCI) domain	Domain
VA [auth u]	IPR016024	Armadillo-type fold	Homologous Superfamily
VA [auth u]	IPR040750	eIF3 subunit M, C-terminal helix domain	Domain
VA [auth u]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
VA [auth u]	IPR027528	Eukaryotic translation initiation factor 3 subunit M	Family
UA [auth t]	IPR000717	Proteasome component (PCI) domain	Domain
UA [auth t]	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
UA [auth t]	IPR019382	Translation initiation factor 3 complex subunit L	Family
TA [auth s]	IPR016024	Armadillo-type fold	Homologous Superfamily
TA [auth s]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
TA [auth s]	IPR033464	CSN8/PSMD8/EIF3K	Domain
TA [auth s]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
TA [auth s]	IPR016020	Translation initiation factor 3, subunit 12, N-terminal, eukaryotic	Homologous Superfamily
TA [auth s]	IPR000717	Proteasome component (PCI) domain	Domain
TA [auth s]	IPR009374	Eukaryotic translation initiation factor 3 subunit K	Family
SA [auth r]	IPR037518	MPN domain	Domain
SA [auth r]	IPR027524	Eukaryotic translation initiation factor 3 subunit H	Family
SA [auth r]	IPR045810	eIF3h, C-terminal	Domain
SA [auth r]	IPR050242	JAMM/MPN+ metalloenzymes, peptidase M67A	Family
SA [auth r]	IPR000555	JAB1/MPN/MOV34 metalloenzyme domain	Domain
RA [auth q]	IPR027531	Eukaryotic translation initiation factor 3 subunit F	Family
RA [auth q]	IPR024969	EIF3F/CSN6-like, C-terminal	Domain
RA [auth q]	IPR037518	MPN domain	Domain
RA [auth q]	IPR000555	JAB1/MPN/MOV34 metalloenzyme domain	Domain
QA [auth o]	IPR016190	Translation initiation factor IF2/IF5, zinc-binding	Homologous Superfamily
QA [auth o]	IPR016024	Armadillo-type fold	Homologous Superfamily
QA [auth o]	IPR016189	Translation initiation factor IF2/IF5, N-terminal	Homologous Superfamily
QA [auth o]	IPR003307	W2 domain	Domain
QA [auth o]	IPR002735	Translation initiation factor IF2/IF5 domain	Domain
QA [auth o]	IPR045196	Translation initiation factor IF2/IF5	Family
PA [auth n]	IPR004977	Small ribosomal subunit protein eS25	Family
PA [auth n]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
OA [auth m]	IPR007783	Eukaryotic translation initiation factor 3 subunit D	Family
NA [auth l]	IPR007836	Large ribosomal subunit protein eS32	Family
D [auth A]	IPR003029	S1 domain	Domain
D [auth A]	IPR044126	IF2a, S1-like domain	Domain
D [auth A]	IPR024054	Translation initiation factor 2, alpha subunit, middle domain superfamily	Homologous Superfamily
D [auth A]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
D [auth A]	IPR024055	Translation initiation factor 2, alpha subunit, C-terminal	Homologous Superfamily
D [auth A]	IPR011488	Translation initiation factor 2, alpha subunit	Family
MA [auth k]	IPR007209	RNase L inhibitor RLI-like, possible metal-binding domain	Domain
MA [auth k]	IPR017871	ABC transporter-like, conserved site	Conserved Site
MA [auth k]	IPR003439	ABC transporter-like, ATP-binding domain	Domain
MA [auth k]	IPR017900	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Conserved Site
MA [auth k]	IPR003593	AAA+ ATPase domain	Domain
MA [auth k]	IPR017896	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Domain
MA [auth k]	IPR013283	RLI1	Family
MA [auth k]	IPR034348	RLI, domain 1	Domain
MA [auth k]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
LA [auth j]	IPR018104	Translation initiation factor 1A (eIF-1A), conserved site	Conserved Site
LA [auth j]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
LA [auth j]	IPR006196	RNA-binding domain, S1, IF1 type	Domain
LA [auth j]	IPR001253	Translation initiation factor 1A (eIF-1A)	Family
KA [auth i]	IPR039415	Ubiquitin-like protein FUBI	Domain
KA [auth i]	IPR019956	Ubiquitin domain	Domain
KA [auth i]	IPR019954	Ubiquitin conserved site	Conserved Site
KA [auth i]	IPR029071	Ubiquitin-like domain superfamily	Homologous Superfamily
KA [auth i]	IPR000626	Ubiquitin-like domain	Domain
KA [auth i]	IPR006846	Small ribosomal subunit protein eS30	Family
JA [auth g]	IPR019775	WD40 repeat, conserved site	Conserved Site
JA [auth g]	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
JA [auth g]	IPR045223	Small ribosomal subunit protein RACK1-like	Family
JA [auth g]	IPR020472	PAC1/LIS1-like, WD-40 repeat	Repeat
JA [auth g]	IPR001680	WD40 repeat	Repeat
JA [auth g]	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
IA [auth f]	IPR019954	Ubiquitin conserved site	Conserved Site
IA [auth f]	IPR000626	Ubiquitin-like domain	Domain
IA [auth f]	IPR038582	Small ribosomal subunit protein eS31 eukaryotic superfamily	Homologous Superfamily
IA [auth f]	IPR002906	Small ribosomal subunit protein eS31	Domain
IA [auth f]	IPR019956	Ubiquitin domain	Domain
IA [auth f]	IPR050158	Ubiquitin and ubiquitin-like	Family
IA [auth f]	IPR029071	Ubiquitin-like domain superfamily	Homologous Superfamily
IA [auth f]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
HA [auth e]	IPR001209	Small ribosomal subunit protein uS14	Family
HA [auth e]	IPR018271	Small ribosomal subunit protein uS14, conserved site	Conserved Site
HA [auth e]	IPR039744	Small ribosomal subunit protein uS14, eukaryotes/archaea	Family
HA [auth e]	IPR043140	Small ribosomal subunit protein uS14 superfamily	Homologous Superfamily
GA [auth d]	IPR028626	Ribosomal protein eS28 conserved site	Conserved Site
GA [auth d]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
GA [auth d]	IPR000289	Small ribosomal subunit protein eS28	Family
FA [auth c]	IPR023407	Small ribosomal subunit protein eS27, zinc-binding domain superfamily	Homologous Superfamily
FA [auth c]	IPR000592	Small ribosomal subunit protein eS27	Family
FA [auth c]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
EA [auth b]	IPR038551	Ribosomal protein eS26 superfamily	Homologous Superfamily
EA [auth b]	IPR000892	Small ribosomal subunit protein eS26	Family
EA [auth b]	IPR047864	Ribosomal protein eS26, conserved site	Conserved Site
DA [auth a]	IPR053709	Eukaryotic Ribosomal Protein eS24	Homologous Superfamily
DA [auth a]	IPR001976	Small ribosomal subunit protein eS24	Family
DA [auth a]	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
DA [auth a]	IPR018098	Small ribosomal subunit protein eS24 conserved site	Conserved Site
CA [auth Z]	IPR006032	Small ribosomal subunit protein uS12	Family
CA [auth Z]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
CA [auth Z]	IPR005680	Small ribosomal subunit protein uS12, eukaryota/archaea	Family
BA [auth Y]	IPR000630	Small ribosomal subunit protein uS8	Family
BA [auth Y]	IPR047863	Small ribosomal subunit protein uS8, conserved site	Conserved Site
BA [auth Y]	IPR035987	Small ribosomal subunit protein uS8 superfamily	Homologous Superfamily
AA [auth X]	IPR038579	Small ribosomal subunit protein eS21 superfamily	Homologous Superfamily
AA [auth X]	IPR018279	Small ribosomal subunit protein eS21, conserved site	Conserved Site
AA [auth X]	IPR001931	Small ribosomal subunit protein eS21	Family
Z [auth W]	IPR001848	Small ribosomal subunit protein uS10	Family
Z [auth W]	IPR027486	Small ribosomal subunit protein uS10 domain	Domain
Z [auth W]	IPR036838	Small ribosomal subunit protein uS10 domain superfamily	Homologous Superfamily
Z [auth W]	IPR005729	Small ribosomal subunit protein uS10, eukaryotic/archaeal	Family
Z [auth W]	IPR018268	Small ribosomal subunit protein uS10, conserved site	Conserved Site
Y [auth V]	IPR001266	Small ribosomal subunit protein eS19	Family
Y [auth V]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
Y [auth V]	IPR018277	Small ribosomal subunit protein eS19, conserved site	Conserved Site
Y [auth V]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
X [auth U]	IPR027437	Small ribosomal subunit protein uS13, C-terminal	Homologous Superfamily
X [auth U]	IPR001892	Small ribosomal subunit protein uS13	Family
X [auth U]	IPR018269	Small ribosomal subunit protein uS13, conserved site	Conserved Site
X [auth U]	IPR010979	Small ribosomal subunit protein uS13-like, H2TH	Homologous Superfamily
W [auth T]	IPR036401	Small ribosomal subunit protein eS17 superfamily	Homologous Superfamily
W [auth T]	IPR001210	Small ribosomal subunit protein eS17	Family
W [auth T]	IPR018273	Small ribosomal subunit protein eS17, conserved site	Conserved Site
V [auth S]	IPR020574	Small ribosomal subunit protein uS9, conserved site	Conserved Site
V [auth S]	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
V [auth S]	IPR000754	Small ribosomal subunit protein uS9	Family
V [auth S]	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
U [auth R]	IPR023575	Small ribosomal subunit protein uS19, superfamily	Homologous Superfamily
U [auth R]	IPR020934	Small ribosomal subunit protein uS19, conserved site	Conserved Site
U [auth R]	IPR002222	Small ribosomal subunit protein uS19	Family
U [auth R]	IPR005713	Small ribosomal subunit protein uS19, eukaryota/archaea	Family
T [auth Q]	IPR001971	Small ribosomal subunit protein uS11	Family
T [auth Q]	IPR036967	Small ribosomal subunit protein uS11 superfamily	Homologous Superfamily
T [auth Q]	IPR018102	Small ribosomal subunit protein uS11, conserved site	Conserved Site
S [auth P]	IPR012606	Small ribosomal subunit protein uS15, N-terminal	Domain
S [auth P]	IPR009068	uS15/NS1, RNA-binding domain superfamily	Homologous Superfamily
S [auth P]	IPR023029	Small ribosomal subunit protein uS15, archaea/eukaryota	Family
S [auth P]	IPR000589	Small ribosomal subunit protein uS15	Family
R [auth O]	IPR000530	Small ribosomal subunit protein eS12	Family
R [auth O]	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
R [auth O]	IPR047860	Small ribosomal subunit protein eS12, conserved site	Conserved Site
R [auth O]	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
Q [auth N]	IPR019979	Small ribosomal subunit protein uS17, conserved site	Conserved Site
Q [auth N]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
Q [auth N]	IPR000266	Small ribosomal subunit protein uS17	Family
Q [auth N]	IPR032440	Small ribosomal subunit protein uS17, N-terminal	Domain
Q [auth N]	IPR028333	Small ribosomal subunit protein uS17, archaeal/eukaryotic	Family
P [auth M]	IPR037447	Small ribosomal subunit protein eS10	Family
P [auth M]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
P [auth M]	IPR005326	Plectin/eS10, N-terminal	Domain
O [auth L]	IPR002942	RNA-binding S4 domain	Domain
O [auth L]	IPR022801	Small ribosomal subunit protein uS4	Family
O [auth L]	IPR005710	Small ribosomal subunit protein uS4, eukaryota/archaea	Family
O [auth L]	IPR018079	Small ribosomal subunit protein uS4, conserved site	Conserved Site
O [auth L]	IPR001912	Small ribosomal subunit protein uS4, N-terminal	Domain
O [auth L]	IPR036986	RNA-binding S4 domain superfamily	Homologous Superfamily
N [auth K]	IPR001047	Small ribosomal subunit protein eS8	Family
N [auth K]	IPR042563	Small ribosomal subunit protein eS8 subdomain, eukaryota	Homologous Superfamily
N [auth K]	IPR022309	Ribosomal protein eS8/ribosomal biogenesis NSA2	Family
N [auth K]	IPR018283	Small ribosomal subunit protein eS8, conserved site	Conserved Site
M [auth J]	IPR000554	Small ribosomal subunit protein eS7	Family
M [auth J]	IPR047861	Small ribosomal subunit protein eS7, conserved site	Conserved Site
L [auth I]	IPR014401	Small ribosomal subunit protein eS6-like	Family
L [auth I]	IPR001377	Small ribosomal subunit protein eS6	Family
L [auth I]	IPR018282	Small ribosomal subunit protein eS6, conserved site	Conserved Site
K [auth H]	IPR020606	Small ribosomal subunit protein uS7, conserved site	Conserved Site
K [auth H]	IPR000235	Small ribosomal subunit protein uS7	Family
K [auth H]	IPR036823	Small ribosomal subunit protein uS7 domain superfamily	Homologous Superfamily
K [auth H]	IPR023798	Small ribosomal subunit protein uS7 domain	Domain
K [auth H]	IPR005716	Ribosomal protein uS7, eukaryotic/archaeal	Family
J [auth G]	IPR018199	Small ribosomal subunit protein eS4, N-terminal, conserved site	Conserved Site
J [auth G]	IPR013843	Small ribosomal subunit protein eS4, N-terminal	Domain
J [auth G]	IPR032277	Small ribosomal subunit protein eS4, C-terminal domain	Domain
J [auth G]	IPR002942	RNA-binding S4 domain	Domain
J [auth G]	IPR013845	Small ribosomal subunit protein eS4, central region	Domain
J [auth G]	IPR000876	Small ribosomal subunit protein eS4	Family
J [auth G]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
J [auth G]	IPR038237	Small ribosomal subunit protein eS4, central domain superfamily	Homologous Superfamily
J [auth G]	IPR041982	Small ribosomal subunit protein eS4, KOW domain	Domain
J [auth G]	IPR036986	RNA-binding S4 domain superfamily	Homologous Superfamily
J [auth G]	IPR005824	KOW	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
LA [auth j]	Pharos: P47813	uveal melanoma Neoplasm Metastasis atypical teratoid rhabdoid tumor ovarian cancer sarcoidosis breast cancer ocular melanoma pancreatic intraductal papillary-mucinous neoplasm thyroid gland papillary carcinoma lung cancer osteosarcoma psoriasis