9N8N | pdb_00009n8n

Tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
E [auth I]PF07422Sexual stage antigen s48/45 domain (s48_45)Sexual stage antigen s48/45 domainThis family contains sexual stage s48/45 antigens from Plasmodium (approximately 450 residues long). These are surface proteins expressed by Plasmodium male and female gametes that have been shown to play a conserved and important role in fertilisati ...This family contains sexual stage s48/45 antigens from Plasmodium (approximately 450 residues long). These are surface proteins expressed by Plasmodium male and female gametes that have been shown to play a conserved and important role in fertilisation [1]. This domain contains 6 conserved cysteines suggesting 3 disulphide bridges.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
RUPA-39 heavy chain---
E [auth I]Gametocyte surface protein P230,Gametocyte surface protein P45/48- -
D [auth F]RUPA-44 heavy chain---
C [auth E]RUPA-44 Kappa chain---
RUPA-39 Kappa chain---