Beta/kappa-theraphotoxin-Cg1a

UniProtKB accession: P62520

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Polymer Entities matching query 2

Go to UniProtKB: P62520

UniProtKB description: Selectively inhibits activation of voltage-gated sodium channels (VGSC) (Nav1.5/SCN5A) in rat cardiac myocytes, followed by shifting activated voltage in a depolarizing direction. The binding site on VGSC is suggested to be site 4 located at the extracellular S3-S4 loop of the channel. Also binds to voltage-gated potassium channels (Kv2.1/KCNB1).

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