Download MendeleyCrystal structure of ARFGAP1-ARF1 fusion protein
Wang, H., Tong, Y., Nedyalkova, L., Tempel, W., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H.To be published.
3O47 | pdb_00003o47
Crystal structure of ARFGAP1-ARF1 fusion protein
- PDB DOI: https://doi.org/10.2210/pdb3O47/pdb
- Classification: HYDROLASE, HYDROLASE ACTIVATOR
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2010-07-26 Released: 2010-08-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.243 (Depositor), 0.250 (DCC)
- R-Value Work: 0.206 (Depositor), 0.220 (DCC)
- R-Value Observed: 0.207 (Depositor)
Starting Models: experimental
View more details
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1 | 329 | Homo sapiens | Mutation(s): 0 Gene Names: ARFGAP1, ARF1GAP, ARF1 EC: 3.6.5.2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P84077 (Homo sapiens) Explore P84077 Go to UniProtKB: P84077 | |||||
PHAROS: P84077 GTEx: ENSG00000143761 | |||||
Find proteins for Q8N6T3 (Homo sapiens) Explore Q8N6T3 Go to UniProtKB: Q8N6T3 | |||||
PHAROS: Q8N6T3 GTEx: ENSG00000101199 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Groups | P84077Q8N6T3 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GDP Query on GDP | D [auth A], F [auth B] | GUANOSINE-5'-DIPHOSPHATE C10 H15 N5 O11 P2 QGWNDRXFNXRZMB-UUOKFMHZSA-N |  | ||
| ZN Query on ZN | C [auth A], E [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.243 (Depositor), 0.250 (DCC)
- R-Value Work: 0.206 (Depositor), 0.220 (DCC)
- R-Value Observed: 0.207 (Depositor)
Space Group: I 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 79.298 | α = 90 |
| b = 129.161 | β = 90 |
| c = 157.685 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
| BUSTER-TNT | refinement |
| PDB_EXTRACT | data extraction |
| BUSTER | refinement |
Entry History
Deposition Data
- Released Date: 2010-08-11 Deposition Author(s): Wang, H., Tong, Y., Nedyalkova, L., Tempel, W., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2010-08-11
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2017-08-09
Changes: Refinement description, Source and taxonomy - Version 1.3: 2017-11-08
Changes: Refinement description - Version 1.4: 2023-09-06
Changes: Data collection, Database references, Derived calculations, Refinement description
