Download MendeleyCrystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate
Gileadi, T., Wernimont, A.K., Hills, T., Hui, R., Pizarro, J.C.To be published.
3PR3 | pdb_00003pr3
Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate
- PDB DOI: https://doi.org/10.2210/pdb3PR3/pdb
- Classification: ISOMERASE
- Organism(s): Plasmodium falciparum 3D7
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2010-11-29 Released: 2011-02-09
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.45 Å
- R-Value Free: 0.197 (Depositor), 0.200 (DCC)
- R-Value Work: 0.140 (Depositor), 0.140 (DCC)
- R-Value Observed: 0.143 (Depositor)
Starting Model: experimental
View more details
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glucose-6-phosphate isomerase | 597 | Plasmodium falciparum 3D7 | Mutation(s): 0 Gene Names: PF14_0341 EC: 5.3.1.9 |  | |
UniProt | |||||
Find proteins for Q8ILA4 (Plasmodium falciparum (isolate 3D7)) Explore Q8ILA4 Go to UniProtKB: Q8ILA4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8ILA4 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| F6P Query on F6P | C [auth A], E [auth B] | 6-O-phosphono-beta-D-fructofuranose C6 H13 O9 P BGWGXPAPYGQALX-ARQDHWQXSA-N |  | ||
| PO4 Query on PO4 | D [auth A], F [auth B] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.45 Å
- R-Value Free: 0.197 (Depositor), 0.200 (DCC)
- R-Value Work: 0.140 (Depositor), 0.140 (DCC)
- R-Value Observed: 0.143 (Depositor)
Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 72.424 | α = 90 |
| b = 118.325 | β = 117.3 |
| c = 73.042 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| BUSTER-TNT | refinement |
| PDB_EXTRACT | data extraction |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
| BUSTER | refinement |
Entry History
Deposition Data
- Released Date: 2011-02-09 Deposition Author(s): Gileadi, T., Wernimont, A.K., Hutchinson, A., Weadge, J., Cossar, D., Lew, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Hills, T., Pizarro, J.C., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2011-02-09
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2013-10-23
Changes: Structure summary - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Data collection, Database references, Derived calculations, Structure summary - Version 1.4: 2023-09-06
Changes: Data collection, Database references, Refinement description, Structure summary
