Download MendeleyCrystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
Zhang, M.-Y., Lin, P., Zhu, P., Chen, Z.-N.To be published.
5X4G
Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8
- PDB DOI: https://doi.org/10.2210/pdb5X4G/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Mus musculus
- Expression System: Mus musculus
- Mutation(s): No
- Deposited: 2017-02-13 Released: 2018-01-24
- Funding Organization(s): National Science and Technology Major Project, National Basic Research Program of China
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.226
- R-Value Work: 0.206
- R-Value Observed: 0.207
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 6H8 Fab heavy chain | 241 | Mus musculus | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 6H8 Fab light chain | 234 | Mus musculus | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.226
- R-Value Work: 0.206
- R-Value Observed: 0.207
- Space Group: P 2 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 40.104 | α = 90 |
| b = 100.448 | β = 90 |
| c = 108.175 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2018-01-24 Deposition Author(s): Lin, P., Zhang, M.-Y., Chen, X., Ye, S., Yu, X.-L., Zhang, R.-G., Zhu, P., Chen, Z.-N.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Science and Technology Major Project | China | 2013ZX09301301 |
| National Basic Research Program of China | China | 2015CB553701 |
Revision History (Full details and data files)
- Version 1.0: 2018-01-24
Type: Initial release - Version 1.1: 2024-10-23
Changes: Data collection, Database references, Structure summary
