9K6L | pdb_00009k6l

Cryo-EM structure of GPCR16-Gi2 complex


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 2.77 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

wwPDB Validation   3D Report Full Report


This is version 1.0 of the entry. See complete history


Literature

Cryo-EM structure of GPCR16-Gi2 complex

Wang, X.Zhou, C.Wu, L.J.Hua, T.Liu, Z.J.

To be published.

Macromolecules
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Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Guanine nucleotide-binding protein G(i) subunit alpha-2355Homo sapiensMutation(s): 3 
Gene Names: GNAI2GNAI2B
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Find proteins for P04899 (Homo sapiens)
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PHAROS:  P04899
GTEx:  ENSG00000114353 
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UniProt GroupP04899
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Entity ID: 2
MoleculeChains Sequence LengthOrganismDetailsImage
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1366Homo sapiensMutation(s): 0 
Gene Names: GNB1
UniProt & NIH Common Fund Data Resources
Find proteins for P62873 (Homo sapiens)
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PHAROS:  P62873
GTEx:  ENSG00000078369 
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UniProt GroupP62873
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Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2C [auth G]71Homo sapiensMutation(s): 0 
Gene Names: GNG2
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Find proteins for P59768 (Homo sapiens)
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PHAROS:  P59768
GTEx:  ENSG00000186469 
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UniProt GroupP59768
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Entity ID: 4
MoleculeChains Sequence LengthOrganismDetailsImage
scFv16D [auth S]266Homo sapiensMutation(s): 0 
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Entity ID: 5
MoleculeChains Sequence LengthOrganismDetailsImage
exo-alpha-sialidase,Taste receptor type 2 member 16,LgBiTE [auth R]1,011Streptococcus pneumoniaeHomo sapienssynthetic construct
This entity is chimeric
Mutation(s): 1 
Gene Names: nanA_2SAMEA3353537_00427TAS2R16
EC: 3.2.1.18
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PHAROS:  Q9NYV7
GTEx:  ENSG00000128519 
Find proteins for A0A4J2AMT3 (Streptococcus pneumoniae)
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Go to UniProtKB:  A0A4J2AMT3
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UniProt GroupsQ9NYV7A0A4J2AMT3
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Small Molecules
Ligands 1 Unique
IDChains Name / Formula / InChI Key2D Diagram3D Interactions
SA0 (Subject of Investigation/LOI)
Query on SA0

Download Ideal Coordinates CCD File 
F [auth R]2-(hydroxymethyl)phenyl beta-D-glucopyranoside
C13 H18 O7
NGFMICBWJRZIBI-UJPOAAIJSA-N
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 2.77 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

Structure Validation

View Full Validation Report



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
Not funded--

Revision History  (Full details and data files)

  • Version 1.0: 2025-04-02
    Type: Initial release