9DQV | pdb_00009dqv

Structure of western equine encephalitis virus CBA87 VLP in complex with human PCDH10 EC1

External Resource: Annotation


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
C [auth F],
F [auth I],
I [auth L],
O [auth C]		PF00944Alphavirus core protein (Peptidase_S3)Alphavirus core proteinAlso known as coat protein C and capsid protein C. This makes the literature very confusing. Alphaviruses consist of a nucleoprotein core, a lipid membrane which envelopes the core, and glycoprotein spikes protruding from the lipid membrane. Domain
J [auth M],
K [auth N],
L [auth O],
P		PF08266Cadherin-like (Cadherin_2)Cadherin-likeThis cadherin domain is usually the most N-terminal copy of the domain. Domain
A [auth D],
D [auth G],
G [auth J],
M [auth A]		PF01589Alphavirus E1 glycoprotein (Alpha_E1_glycop)Alphavirus E1 glycoprotein- Family
B [auth E],
E [auth H],
H [auth K],
N [auth B]		PF00943Alphavirus E2 glycoprotein (Alpha_E2_glycop)Alphavirus E2 glycoprotein- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
C [auth F],
F [auth I],
I [auth L],
O [auth C]		Capsid protein
J [auth M],
K [auth N],
L [auth O],
P		Protocadherin-10
A [auth D],
D [auth G],
G [auth J],
M [auth A]		Structural polyprotein
B [auth E],
E [auth H],
H [auth K],
N [auth B]		Structural polyprotein

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR002533Alphavirus E3 spike glycoproteinDomain
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR038055Flaviviral glycoprotein E, dimerisation domainHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR014756Immunoglobulin E-setHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR042304Alphavirus E2 glycoprotein, domain AHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR036253Flavivirus glycoprotein, central and dimerisation domain superfamilyHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR009003Peptidase S1, PA clanHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR042305Alphavirus E2 glycoprotein, domain BHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR042306Alphavirus E2 glycoprotein, domain CHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR000936Alphavirus E2 glycoproteinFamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR000930Peptidase S3, togavirinDomain
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR002548Alphavirus E1 glycoproteinDomain
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR000336Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamilyHomologous Superfamily
C [auth F],
F [auth I],
I [auth L],
O [auth C]		IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
J [auth M],
K [auth N],
L [auth O],
P		IPR032455Cadherin, cytoplasmic C-terminal domainDomain
J [auth M],
K [auth N],
L [auth O],
P		IPR050174Protocadherin/Cadherin-related Cell AdhesionFamily
J [auth M],
K [auth N],
L [auth O],
P		IPR013164Cadherin, N-terminalDomain
J [auth M],
K [auth N],
L [auth O],
P		IPR015919Cadherin-like superfamilyHomologous Superfamily
J [auth M],
K [auth N],
L [auth O],
P		IPR020894Cadherin conserved siteConserved Site
J [auth M],
K [auth N],
L [auth O],
P		IPR002126Cadherin-likeDomain
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR002533Alphavirus E3 spike glycoproteinDomain
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR009003Peptidase S1, PA clanHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR042305Alphavirus E2 glycoprotein, domain BHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR042306Alphavirus E2 glycoprotein, domain CHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR000936Alphavirus E2 glycoproteinFamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR038055Flaviviral glycoprotein E, dimerisation domainHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR000930Peptidase S3, togavirinDomain
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR014756Immunoglobulin E-setHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR042304Alphavirus E2 glycoprotein, domain AHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR002548Alphavirus E1 glycoproteinDomain
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR000336Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamilyHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR036253Flavivirus glycoprotein, central and dimerisation domain superfamilyHomologous Superfamily
A [auth D],
D [auth G],
G [auth J],
M [auth A]		IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR002533Alphavirus E3 spike glycoproteinDomain
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR009003Peptidase S1, PA clanHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR042305Alphavirus E2 glycoprotein, domain BHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR042306Alphavirus E2 glycoprotein, domain CHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR000936Alphavirus E2 glycoproteinFamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR038055Flaviviral glycoprotein E, dimerisation domainHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR000930Peptidase S3, togavirinDomain
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR014756Immunoglobulin E-setHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR042304Alphavirus E2 glycoprotein, domain AHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR002548Alphavirus E1 glycoproteinDomain
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR000336Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamilyHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR036253Flavivirus glycoprotein, central and dimerisation domain superfamilyHomologous Superfamily
B [auth E],
E [auth H],
H [auth K],
N [auth B]		IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
J [auth M],
K [auth N],
L [auth O],
P		Pharos:  Q9P2E7